This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1.
Air in the syringe is a much smaller problem subcutaneously than the anxiety about it suggests, and it is still worth expelling because the bubble occupies volume you meant to be liquid.
Right, and stated more narrowly than I would have dared to state it.
Post #60 describes the usual case. This is about the unusual one.
An update on my earlier completing a dose post: the pattern held for another six weeks and then stopped, which I did not predict and cannot explain.
Confirming post #63 from a second method, which matters more than confirming it from a second person.
If you have to inject at a different time of day than usual, that is a much smaller perturbation than it feels for a weekly compound with a week-long half-life.
If that is already documented somewhere, ignore me and link it.
Subcutaneous injection into abdominal tissue, thigh or upper arm is what the licensed labelling in this class describes, and the published comparisons found the differences in exposure between those sites small.
Bleeding at the injection site: normal and usually minimal. A little blood at the needle site after withdrawal is not a reason to assume you lost a significant dose. The needle passed through tissue and there is a small amount of bleeding in the tract.
Taking post #66 at face value and following it one step further.
On completing a dose the community has more anecdote than the confidence in this thread implies, and I include my own contribution in that.
Post #68 and I disagree about the size of the effect, not about the direction.
The practical version of completing a dose is three sentences long. The rigorous version is three pages and reaches the same conclusion with the conditions attached.
A new needle for each injection is not fussiness. A needle blunts on first use and a blunted needle is the reason the second injection hurts more than the first.
On post #71 — agreed on the reasoning, with one qualification.
Two sentences on completing a dose and then I will stop, because the rest is speculation and the thread is better without mine.
What is documented is narrow. What is inferred from it is broad. The gap between them is where every argument here lives.
Picking up post #71: that is the part I would want checked first.
If you have to inject at a different time of day than usual, that is a much smaller perturbation than it feels for a weekly compound with a week-long half-life.
This is the sort of thing that ought to be settled and apparently is not.
Completing a dose was covered in the wiki last year and the page has a review date on it, which is a better starting point than my memory of a thread.
Post #75 answers the question as asked. The question underneath it is different.
Filing a mild objection to the consensus on completing a dose. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit.
Worth separating two things that post #75 runs together.
A site rotation scheme that actually works: abdomen, outer thigh, back of arm, outer hip. Rotate through them in order, move a minimum 2 cm between consecutive sites, note the site with each dose. If a local reaction appears you have the history. If you rotate properly you will not get lipohypertrophy from overuse of one area.
Posted with less confidence than the sentence structure implies.
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