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Outcomes · Body composition · continued

DXA precision and the least significant change for lean mass — the long version posts 61–90

This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1.

BV
bias_varianceTL4Biostatistician18 May 2025#61

Nobody has said the unglamorous part of DXA precision yet, so: most of the variation is explained by things that are boring to write about and easy to check.

15 likes 14mo
MS
m.steinerTL219 May 2025#62

Coming back to post #58, because the follow-up matters more than the original answer.

Bone mineral density changes with substantial weight loss are measurable and slow, and are one of the better reasons to have a baseline scan.

For what it is worth, the same held on the two occasions I checked.

30 likes 14mo
FD
f.demirTL2Regular19 May 2025#63
two_year_line, post #7: The arithmetic in post #6 is right; the assumption feeding it is the part to check. What I would check first on DXA precision is whether the thing being measured moved or whether the way of measuring it moved. Those look identical in a graph. Go to post

Acknowledging rather than arguing. The reasoning holds as far as I can follow it.

0 likes in reply to #7 14mo
AI
a.iyerTL219 May 2025#64

Where a facility reports a precision figure for its own machine, that number is more useful than any published average.

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RM
r.mcalisterTL3Regular19 May 2025#65

Comparison to published data: the trials reported mean fat and lean mass changes. Individual results vary around that mean. Being above or below average is not a sign of something wrong.

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RN
r.nakamuraTL219 May 2025#66

Maintenance phase: tracking body composition during maintenance (weight stable) is different from tracking during active loss. Changes are smaller and precision becomes more important.

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DT
dexa_twice_yearlyTL3Regular20 May 2025#67
lc_gradient, post #1: On the subject in the title: DXA precision and the least significant change for lean mass — the long version Working notes rather than a conclusion. A question about measurement precision rather than about physiology. Two readings, some weeks apart, on the same equipment, differing by an amount that feels meaningful and may not be. I do… Go to post

This follows post #64 rather than contradicting it.

Lean mass loss during rapid weight reduction: depends on protein intake, resistance training volume, and total energy deficit. Adequate protein and maintaining training intensity both help preserve lean mass.

If the premise is wrong, everything after it is decoration.

1 like in reply to #1 14mo
HF
h.friskTL220 May 2025 · edited#68
vial_table, post #16: Adding the measurement that post #15 says would settle it. The most useful protocol is the one you will actually repeat identically. An imperfect measurement repeated consistently beats a better one repeated carelessly. A qualification I should have led with rather than closed on. Go to post

Precision versus accuracy: the precision you need depends on what question you are answering. "Am I losing fat?" requires less precision than "Is my lean mass preservation within the expected range?"

5 likes in reply to #16 14mo
GP
g.pemberton_ukTL3Regional · UK20 May 2025#69

Preserving lean tissue during a substantial deficit depends on protein intake and a resistance stimulus, and the evidence for both is reasonably strong.

Two sources, same conclusion, and I could not rule out that one copied the other.

6 likes 14mo
NB
n.boatengTL220 May 2025#70
a.lindqvist, post #47: Lean mass loss during rapid weight reduction: depends on protein intake, resistance training volume, and total energy deficit. Adequate protein and maintaining training intensity both help preserve lean mass. Go to post

Lean mass in these measurements includes water, so a change in hydration appears as a change in lean mass.

16 likes in reply to #47 14mo
AP
abstract_peakTL1Member20 May 2025#71

That is consistent with mine, for whatever one more account is worth.

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BC
b.correiaTL221 May 2025#72
h.frisk, post #68: Precision versus accuracy: the precision you need depends on what question you are answering. "Am I losing fat?" requires less precision than "Is my lean mass preservation within the expected range?" Go to post

An update on my earlier DXA precision post: the pattern held for another six weeks and then stopped, which I did not predict and cannot explain.

2 likes in reply to #68 14mo
NR
n.rowntreeTL3Regular21 May 2025#73

Air displacement plethysmography and hydrostatic weighing have their own precision limits and their own protocol sensitivities. None of these are exact.

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RB
r.bakkenTL221 May 2025#74

This follows post #73 rather than contradicting it.

Comparing a body composition result against a population reference is a different exercise from tracking your own change, and the second is what most people want.

28 likes 14mo
I
IsaksenTL3Regular21 May 2025#75

I had written a reply contradicting post #73 and deleted it. Here is what survived.

DXA (dual-energy X-ray absorptiometry): the standard for body composition in research. Precision is roughly ±1 kg for lean mass. Two scans six months apart on the same machine with the same technician give you useful information. Two scans six weeks apart on different machines tell you about the machines.

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TI
t.ibarraTL221 May 2025#76

Confirming post #73 from a second method, which matters more than confirming it from a second person.

The most useful protocol is the one you will actually repeat identically. An imperfect measurement repeated consistently beats a better one repeated carelessly.

Worth checking against a second source before it gets quoted onward.

5 likes 14mo
TN
t.nardoneTL3Regular22 May 2025#77
j.vandermolen, post #48: DXA on the same machine with the same technician has a least significant change for lean mass of roughly a kilogram, sometimes more. Below that, two scans are the same scan. Go to post

DXA precision sits at the boundary between what this community can usefully discuss and what it cannot, and I think it falls on the discussable side, narrowly.

0 likes in reply to #48 14mo
NA
n.achebeTL222 May 2025#78
LC
l.chevalierTL3Regular22 May 2025#79

Resting metabolic rate: body composition affects metabolic rate. As fat mass decreases and lean mass is maintained, metabolic rate is usually maintained better than with simple weight loss alone.

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MA
m.adebayoTL222 May 2025#80

That is a cleaner way of putting what I was circling around.

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SO
s.ostergaardTL222 May 2025#81

Visceral fat: DXA does not distinguish visceral (organ-associated) fat from subcutaneous fat. That distinction might matter but requires different imaging to measure.

5 likes 14mo
BV
bias_varianceTL4Biostatistician23 May 2025#82
lc_gradient, post #1: On the subject in the title: DXA precision and the least significant change for lean mass — the long version Working notes rather than a conclusion. A question about measurement precision rather than about physiology. Two readings, some weeks apart, on the same equipment, differing by an amount that feels meaningful and may not be. I do… Go to post

DXA on the same machine with the same technician has a least significant change for lean mass of roughly a kilogram, sometimes more. Below that, two scans are the same scan.

The uncertainty is in the assumption, not in the calculation.

13 likes in reply to #1 14mo
HD
h.delgadoTL223 May 2025#83
r.vukovic, post #28: Where a facility reports a precision figure for its own machine, that number is more useful than any published average. Worth reading the earlier posts in this thread before acting on mine. Go to post

Narrowing post #82, because the general version has more than one answer.

What I would want before treating DXA precision as settled: the method, the sample, and whether anyone tried to find the opposite result. Two of the three are usually missing.

0 likes in reply to #28 14mo
IT
impurity_tableTL3Analytical chemist23 May 2025#84

Everything in post #81 holds. The case it does not cover is the one I have.

Absolute lean mass and lean mass as a proportion move differently and answer different questions. Report both or say which.

It is worth stating the boring hypothesis before the interesting one.

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AI
a.iyerTL223 May 2025#85

Circumference measurements at marked sites, taken consistently, track composition change better than most people expect for the cost.

The literature is thinner on this than the confidence in the thread implies.

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RM
r.mcalisterTL3Regular23 May 2025#86

This settles it for me, at least until somebody posts a reason it should not.

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MS
m.steinerTL224 May 2025#87
p.fontaine, post #38: Post #36 is right about the mechanism and I think understates the practical bit. Where a scan disagrees with the mirror over a short period, the scan's precision limits are usually the explanation. The part I am sure of is shorter than the part I have written. Go to post

The arithmetic in post #85 is right; the assumption feeding it is the part to check.

Neither method is capable of detecting the month-to-month changes that people report detecting month to month.

I have said this before in a thread nobody could find, so it is worth repeating.

27 likes in reply to #38 14mo
FD
f.demirTL2Regular24 May 2025#88

Taking DXA precision seriously for a moment rather than deflecting: the honest position is that the community has observations and no controlled comparison, and those two things support very different sentences.

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SD
s.dziedzicTL224 May 2025#89

Post #87 is the version of this I will quote in future. One addition.

Adding the boring version of DXA precision, because the interesting version keeps getting posted and the boring one is usually right.

Check the ordinary explanations, in order, and stop when one of them accounts for what you are seeing. Most of the time the second one does.

13 likes 14mo
SC
so.cardosoTL224 May 2025#90

Where I part company with post #88, and it is a narrow parting.

Where a scan disagrees with the mirror over a short period, the scan's precision limits are usually the explanation.

The disagreement above is smaller than it looks once the terms are fixed.

26 likes 14mo