The Peptide CommonsEst. May 2024
Independent. We sell nothing and are affiliated with no manufacturer or pharmacy. Every moderation action is logged in public
Topic summary

Second pass at: Absence of evidence and evidence of absence

This is a generated summary. It shows the 8 most-liked posts from a topic of 56, in their original order, with the accepted answer included where one exists. It is a reading aid and it will miss nuance — the full topic is the record.
GV
g.valckenaereTL3Regular20 May 2026#6

Post #4 describes the usual case. This is about the unusual one.

Percentages of small denominators should be reported with the denominator. Two out of three is not sixty-seven per cent in any useful sense.

Posted with less confidence than the sentence structure implies.

27 likes 2mo
BV
bias_varianceTL4Biostatistician7 Jun 2026#17
s.leclerc, post #1: On the subject in the title: Second pass at: Absence of evidence and evidence of absence Working notes rather than a conclusion. Two things I would like separated before anyone answers on Absence of evidence, because they get bundled and then argued about as one thing. The first is descriptive: what has actually been observed, by whom,… Go to post

I read the earlier replies on Absence of evidence twice before writing this, because I had assumed the opposite and wanted to be sure I was disagreeing with what was said rather than what I expected.

29 likes in reply to #1 2mo
RH
revision_historyTL3Wiki editor16 Jun 2026#23
s.teixeira, post #7: Appreciated. The plain phrasing does more work here than a longer post would. Go to post

Narrowing post #20, because the general version has more than one answer.

The honest answer on Absence of evidence is that it depends, and the useful part is the list of what it depends on. Four items, in rough order of how much they matter.

Most people get the first two right and then argue about the fourth.

27 likes in reply to #7 1mo
N
NardoneTL2Member29 Jun 2026#33

On post #29 — agreed on the reasoning, with one qualification.

Filing a mild objection to the consensus on Absence of evidence. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit.

25 likes 28d
RM
r.molnarTL28 Jul 2026#40
Tamburello, post #37: Adding the boring version of Absence of evidence, because the interesting version keeps getting posted and the boring one is usually right. Check the ordinary explanations, in order, and stop when one of them accounts for what you are seeing. Most of the time the second one does. Go to post

Post #38 answers the question as asked. The question underneath it is different.

Whatever the answer on Absence of evidence turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, invite the correction.

26 likes in reply to #37 20d
DB
da.bakkerTL212 Jul 2026#43
g.valckenaere, post #6: Post #4 describes the usual case. This is about the unusual one. Percentages of small denominators should be reported with the denominator. Two out of three is not sixty-seven per cent in any useful sense. Posted with less confidence than the sentence structure implies. Go to post

This follows post #41 rather than contradicting it.

The practical version of Absence of evidence is three sentences long. The rigorous version is three pages and reaches the same conclusion with the conditions attached.

32 likes in reply to #6 16d
MO
m.oyelaranTL217 Jul 2026#47

Where I would push back on the Absence of evidence consensus is the confidence, not the direction. The direction looks right. The confidence is borrowed.

24 likes 11d
K
KForsbergTL2Member25 Jul 2026#54

A distribution shown is worth ten summary statistics. Where a paper shows individual data points, read those first.

Where I would look next, rather than where I would stop.

22 likes 3d

Read the full topic (56 posts)

Suggested topics

TopicParticipantsRepliesViewsActivity
Measurement error in home scales, with a worked standard deviation — a second dataset
Measurement error in home scales, with a worked standard deviation — a second dataset — setting out what I have, and where I think it stops being reliable. Posting a small dataset on Measurement error in home…
AKKSA 2 13k 7mo
Regression to the mean in progress reports
On the subject in the title: Regression to the mean in progress reports Working notes rather than a conclusion. Something about regression does not reconcile and I would like a second pair of eyes before I…
HAAMTFAVDM+30 34 49k 12mo
Sample size intuition for a personal experiment
On the subject in the title: Sample size intuition for a personal experiment Working notes rather than a conclusion. A follow-up question about sample size intuition that I did not know to ask the first time.…
RKHECAHTT 4 62k 18mo
Measurement error in home scales, with a worked standard deviation — the long version
On the subject in the title: Measurement error in home scales, with a worked standard deviation — the long version Working notes rather than a conclusion. A narrow question about Measurement error in home…
SKRRAWDYJD+96 105 2k 2mo
What a confidence interval means, from scratch — the long version
The question in the title: What a confidence interval means, from scratch — the long version I will give what I have already checked below so nobody repeats it. Asking about confidence interval directly,…
OVTSAWCEBW+16 20 2.3k 8mo

Related topics — sharing the tags worked example, confounding, number needed to treat

TopicParticipantsRepliesViewsActivity
Why "add 2 mL" is not an instruction — a second dataset
Why "add 2 mL" is not an instruction — a second dataset — that is the question, and I have not found it answered plainly anywhere I have looked. I have read the maintained page on this and I still have a gap,…
IDIBDT 2 13k 11mo
Second pass at: Multiplicity when you track fifteen variables
Posting this under the heading it deserves: Second pass at: Multiplicity when you track fifteen variables Everything below is what sits behind that. Two things I would like separated before anyone answers on…
KFFFRM 2 12k 18mo
Journal club: STEP 3 and the intensive behavioural therapy floor — does this still hold?
The question in the title: Journal club: STEP 3 and the intensive behavioural therapy floor — does this still hold? I will give what I have already checked below so nobody repeats it. Asking about STEP 3 on…
SOAFVK 2 15k 10mo
How much context is too much context in a first post?
How much context is too much context in a first post? I have a specific reason for asking rather than idle curiosity, and the context is below. Counting it rather than describing it, because the count is the…
LSHVPMKJD+69 74 935 18d
Regression to the mean in progress reports
On the subject in the title: Regression to the mean in progress reports Working notes rather than a conclusion. Something about regression does not reconcile and I would like a second pair of eyes before I…
HAAMTFAVDM+30 34 49k 12mo