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Lounge · Off topic · continued

The best-written scientific paper you have read posts 31–60

This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1.

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a.almeidaTL25 May 2026#31
a.nascimento, post #17: A methods point on best-written scientific paper rather than a substantive one: if the comparison is not like for like, the difference you are measuring is the difference in method. Go to post

That is clearer than the version I had in my head. Thank you.

22 likes in reply to #17 3mo
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c.correiaTL25 May 2026#32
dr_okonkwo, post #24: Analytics first, in my case, and I still find the practice category the harder read. Chromatography has one right answer more often than logistics does. Somebody will have a better source than mine, and I hope they post it. Go to post

Community norms: if you want to discuss how the community should work (not moderation decisions, which go in Meta) the Lounge is a place for that casual discussion.

0 likes in reply to #24 3mo
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m.malinowskiTL26 May 2026#33

Paper, same. I think it is that writing by hand is slow enough to make you decide what is worth recording.

This is the sort of thing the wiki should carry and currently does not.

1 like 3mo
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p.silvaTL27 May 2026#34

I would be cautious about generalising from the best-written scientific paper example above. It is a good example. It is one example.

6 likes 3mo
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sa.okonkwoTL27 May 2026#35
c.cardoso, post #22: Politics and public policy: healthcare policy that affects access to these compounds is relevant here. Partisan politics is not. Go to post

The reason best-written scientific paper is hard to answer is that the obvious measurement and the relevant quantity are not the same thing, and substituting one for the other is silent.

16 likes in reply to #22 3mo
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a.westergaardTL3Regular8 May 2026#36

A digression that keeps occurring to me: the most-linked documents here are the dullest ones. Nothing gets cited like the unit-arithmetic page.

That is the practical version. The rigorous version is longer and says the same thing.

31 likes 3mo
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t.lindqvistTL29 May 2026 · edited#37

An observation about best-written scientific paper that I cannot explain and am posting anyway, on the principle that unexplained observations are more useful public than private.

0 likes 3mo
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j.delacroixTL3Regular9 May 2026#38

Best-written scientific paper: I would want to see the raw numbers rather than the summary before agreeing. Summaries lose exactly the information that would settle this.

3 likes 3mo
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s.karlsen_rphTL3Pharmacist10 May 2026#39
c.haddad, post #13: Taking best-written scientific paper seriously for a moment rather than deflecting: the honest position is that the community has observations and no controlled comparison, and those two things support very different sentences. Go to post

Science communication: if you come across an interesting science paper or article about peptides or metabolism, sharing it and discussing the idea is on-topic.

The uncertainty is in the assumption, not in the calculation.

11 likes in reply to #13 3mo
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o.vukovicTL210 May 2026#40

Quietly grateful for the plain phrasing. Not every thread gets that.

23 likes 3mo
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ak.kravchenkoTL211 May 2026#41
p.mwangi, post #27: Nothing to add, except that this is the answer I would give if asked. Go to post

Agreed, and the corollary is that a place with no visible corrections is not a place with fewer errors.

0 likes in reply to #27 3mo
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integrator_traceTL2Member12 May 2026#42

Best-written scientific paper looks different depending on whether you are reading the primary literature or the summaries of it, and the difference is not in our favour.

25 likes 3mo
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n.kirchnerTL212 May 2026#43

Loosely related and not worth its own topic: the vocabulary here has leaked into how I read everything. I now notice when a press release gives a relative figure and no absolute one, which is most of the time.

Take it as a starting point and not as a specification.

7 likes 3mo
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a.schaefferTL2Member13 May 2026 · edited#44

The practical version of best-written scientific paper is three sentences long. The rigorous version is three pages and reaches the same conclusion with the conditions attached.

1 like 3mo
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h.kimaniTL214 May 2026#45
n.broberg, post #25: The most useful reply I ever got about best-written scientific paper was a request to state my units. It sounds like pedantry and it has saved me twice. Go to post

Useful. I have added it to my own notes with the date on it.

0 likes in reply to #25 2mo
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BDraganovTL2Member14 May 2026#46
k.brandl_de, post #16: Lounge question, no agenda: does anyone else keep a physical notebook for this rather than a file? Mine is more use than anything I have typed, and I cannot entirely explain why. Go to post

Analytics first, in my case, and I still find the practice category the harder read. Chromatography has one right answer more often than logistics does.

That matches what I was told, which is not the same as knowing it.

18 likes in reply to #16 2mo
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t.marchettiTL215 May 2026#47

Careful with the language on best-written scientific paper. "Not detected" and "not present" are different findings and the first is a statement about the method.

0 likes 2mo
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h.almeidaTL2Member16 May 2026#48

Best-written scientific paper: I have looked for the primary source twice and failed twice. Either it does not exist or it is somewhere I do not know to look, and I would like to know which.

26 likes 2mo
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p.novakTL216 May 2026#49

That is true everywhere. The reference material that gets used is the material that answers a question you have at the moment you have it, and glamour has nothing to do with it.

Stating my assumptions rather than smuggling them in.

1 like 2mo
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t.kulkarniTL3Regular17 May 2026#50

The thing about best-written scientific paper that took me longest to accept is that a plausible mechanism is not evidence of an effect. It is a reason to look, not a result.

0 likes 2mo
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k.marchandTL217 May 2026 · edited#51
o.vukovic, post #40: Quietly grateful for the plain phrasing. Not every thread gets that. Go to post

Lounge-level thought to close on: the measure of this place is that being wrong in public here is cheap. That is a design decision and it took work.

If this contradicts something upthread, the upthread version may well be the better one.

9 likes in reply to #40 2mo
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fr.translation_moTL2Translator · FR18 May 2026#52

Where I have landed on best-written scientific paper, having got it wrong once in public: the direction is clear, the magnitude is not, and anyone quoting a precise magnitude has borrowed it from somewhere that did not measure it.

20 likes 2mo
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r.weissTL219 May 2026#53

Worth separating best-written scientific paper as a question about the compound from best-written scientific paper as a question about the documentation. They get answered by different people and only one of them is answerable here.

0 likes 2mo
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aliquot_lineTL3Regular19 May 2026#54

Adjacent and interesting: you might post something about nutrition, bioavailability from a food perspective, or the sociology of weight. Adjacent to this community's core but not central.

The part I am sure of is shorter than the part I have written.

2 likes 2mo
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s.adebayoTL220 May 2026#55

Science communication: if you come across an interesting science paper or article about peptides or metabolism, sharing it and discussing the idea is on-topic.

It took me longer than it should have to see that.

13 likes 2mo
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weekly_pinTL2Regular20 May 2026#56

Two things can be true about best-written scientific paper at once: the mechanism is plausible and the evidence for the size of the effect is thin. Most of the argument here is people defending the first against attacks on the second.

28 likes 2mo
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a.delgadoTL221 May 2026#57

Before the thread moves on from best-written scientific paper — what is the sample size behind the claim? I am not being difficult; I have seen the same figure quoted from an n of four and from an n of four hundred.

0 likes 2mo
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m.haddadTL222 May 2026#58
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j.vogelTL222 May 2026#59
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TL4_HalvorsenTL4Leader · Journal club23 May 2026#60
h.almeida, post #48: Best-written scientific paper: I have looked for the primary source twice and failed twice. Either it does not exist or it is somewhere I do not know to look, and I would like to know which. Go to post

Off-topic but genuinely curious: how many people here came in through the analytics side rather than the practical side? The two groups seem to read completely different parts of the site.

Noting that the question and the thing people usually mean by it are different.

9 likes in reply to #48 2mo