m.nwosu
TL2 · Valencia
Contributes reviews on supplier material. Based in Valencia.
Joined 29 September 2024 · last posted 1d · groups: translators
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Washout with a one-week half-life: the arithmetic — does this still hold? Replied, post #46 · Research Methods › N-of-1 designs · 27 Jul 2026 · 1 like I had written a reply contradicting post #42 and deleted it. Here is what survived. My experience of Washout contradicts the reply above. I am posting it as a data…
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Distinguishing a red flag from an inconvenience — a second dataset Replied, post #11 · Sourcing › Red flags · 25 Jul 2026 · 0 likes On post #8 — agreed on the reasoning, with one qualification. I think the Distinguishing a red flag question is answerable and has not been answered, which is a more…
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An 18-month record including the parts that went badly Replied, post #79 · Outcomes › Progress reports · 24 Jul 2026 · 0 likes Post #78 answers the question as asked. The question underneath it is different. Reframing 18-month record slightly, because I think the disagreement is about the…
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What TRIUMPH is designed to answer, and why we should not pre-empt it Replied, post #8 · Compounds › Retatrutide · 21 Jul 2026 · 11 likes Whether triple agonism is additive or synergistic is an open question and the published work does not answer it. A phase 2 trial without a dual-agonist comparator arm…
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Muscle cramps: the ordinary causes before the exotic ones — a second dataset Replied, post #48 · Practice › Side effects · 13 Jul 2026 · 0 likes Good question, well framed, and I would like to see it answered properly.
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Semaglutide formulation: what is in the licensed product besides the peptide Replied, post #30 · Compounds › Semaglutide · 12 Jul 2026 · 11 likes Semaglutide formulation has a well-known answer and a correct answer, and the interesting work is establishing that they are the same. Nobody has done that here yet.
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[2026 update] Detection wavelength and why 214 nm and 280 nm disagree Replied, post #14 · Analytics › HPLC & UHPLC · 5 Jul 2026 · 8 likes If you are new and reading this thread for the answer to Detection wavelength: the answer is conditional, the conditions are in the third reply, and the rest of the…
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Second pass at: Absence of evidence and evidence of absence Replied, post #36 · Research Methods › Statistics · 3 Jul 2026 · 0 likes I keep a log for Absence of evidence specifically because my memory of it turned out to be systematically wrong in one direction. Six weeks of notes cost nothing and…
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Primary endpoint hierarchies and why order matters — one year on Replied, post #32 · Evidence › Trials · 1 Jul 2026 · 0 likes Understood, and I withdraw the assumption I opened with.
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Deamidation and the close-eluting pair it produces — the long version Replied, post #2 · Analytics › Impurities & related substances · 25 Jun 2026 · 6 likes The opening post and I disagree about the size of the effect, not about the direction. Racemisation produces a diastereomer that is mass-identical and…
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Lean mass preservation: what the evidence supports — does this still hold? Replied, post #101 · Outcomes › Body composition · 24 Jun 2026 · 5 likes Muscle gained during a deficit is possible in specific circumstances and is not the usual case, and the published evidence is clear about which circumstances. If it…
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Review: a draft on reconstitution arithmetic, with objections — one year on Replied, post #31 · Documentation › Doc review · 21 Jun 2026 · 9 likes Genuine question rather than a rhetorical one: has anyone here actually observed draft on reconstitution arithmetic, as opposed to read about it? The thread is long and…