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Start Here · How to Ask · continued

Asking a follow-up: new topic or new reply? posts 31–60

This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1 · go to the accepted answer.

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i.beaulieuTL230 Jun 2026#31

Adding a null result on asking a follow-up. I looked, carefully, and found nothing, and null results deserve posting precisely because they never are.

14 likes 28d
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NLoughranTL3Regular1 Jul 2026 · edited#32
micrograms, post #22: The reason asking a follow-up keeps being re-asked is that the answer is conditional and people quote it without the condition. It is not that the answer is unknown. Go to post

Picking up post #31: that is the part I would want checked first.

Asking a follow-up would be much easier to settle if anyone reported the denominator. Almost nobody reports the denominator.

5 likes in reply to #22 27d
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l.lundgrenTL21 Jul 2026#33

I had written a reply contradicting post #31 and deleted it. Here is what survived.

Context that matters: compound, how long in, current dose, relevant history. Context that does not matter: how you feel, your hopes for the outcome, your medical history beyond what affects this specific question. The first set gets you answered. The second set makes the reply longer without making it better.

That is all the detail I have. Someone else will have more.

0 likes 27d
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IMainwaringTL3Regular2 Jul 2026#34

The strongest argument against my own position on asking a follow-up, stated as well as I can state it, since nobody else has yet.

28 likes 26d
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v.okonkwoTL23 Jul 2026#35

Worth separating two things that post #31 runs together.

Asking a follow-up has been discussed here with more heat than it deserves, mostly because two definitions have been in play the whole time.

20 likes 25d
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TamburelloTL2Member3 Jul 2026#36
s.roos, post #29: The question underneath asking a follow-up is usually "how would I tell?" rather than "what is true?", and that one has a method attached to it. Write down what you would expect to see under each hypothesis before you collect anything. If they predict the same observation, collecting it will not help. Go to post

Sensible. I would want the same detail before I acted on it either.

8 likes in reply to #29 24d
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j.cabreraTL24 Jul 2026#37

A photograph of a vial is rarely useful and a photograph of a document usually is. Redact the identifiers before you post either.

Worth checking against a second source before it gets quoted onward.

0 likes 24d
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FFaulknerTL3Regular5 Jul 2026#38

I think the asking a follow-up question is answerable and has not been answered, which is a more optimistic position than most of this thread.

0 likes 23d
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k.batistaTL25 Jul 2026 · edited#39
s.beaulieu, post #6: If the answer you got does not fit your case, say which part does not fit rather than restating the question. Otherwise the next reply is the same as the last one. Go to post

Post #35 and I disagree about the size of the effect, not about the direction.

Asking a follow-up: new topic or reply in the old one? If the answer depends on the previous post, reply. If it is a question that makes sense without the previous post, new topic. The second gets faster answers.

Worth saying I have only my own numbers here, and n is small.

27 likes in reply to #6 22d
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crossover_reviewTL3Regular6 Jul 2026#40

Edit the first post rather than adding the missing detail in reply nine. People arriving later read the first post and stop.

I would want the raw data before agreeing with my own summary of it.

13 likes 22d
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d.barrosTL27 Jul 2026#41

Narrowing post #40, because the general version has more than one answer.

If the answer you got does not fit your case, say which part does not fit rather than restating the question. Otherwise the next reply is the same as the last one.

Anyone who has looked at this more carefully, please correct the record.

24 likes 21d
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h.karlsenTL27 Jul 2026#42

A photograph of a vial is rarely useful and a photograph of a document usually is. Redact the identifiers before you post either.

The claim is narrower than it sounds, and deliberately so.

0 likes 21d
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c.adebayoTL28 Jul 2026#43
a.sorensen, post #10: Post #6 and I disagree about the size of the effect, not about the direction. Chromatogram questions: describe the method first. Column type, gradient, wavelength, detection method. Everything else follows from method. A chromatogram without method is a number without context. Adding this to the thread rather than to the wiki, because I… Go to post

Small methodological point on asking a follow-up: repeating a measurement is cheap and resolves most of what is being argued about here at no cost to anyone.

1 like in reply to #10 20d
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z.yildizTL29 Jul 2026#44

Post #42 and I disagree about the size of the effect, not about the direction.

Where I would push back on the asking a follow-up consensus is the confidence, not the direction. The direction looks right. The confidence is borrowed.

7 likes 19d
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s.ferreiraTL29 Jul 2026 · edited#45

If you are asking about a document, quote the exact wording of the line you are asking about. Paraphrasing a specification is how a discussion ends up about a document nobody has read.

Adding it in case it saves somebody the afternoon it cost me.

32 likes 19d
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o.cousineauTL3Regular10 Jul 2026#46

Tag your own topic. Two accurate tags do more for how findable it is than a long title, and you can change them later.

0 likes 18d
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n.vogelTL211 Jul 2026#47
a.jansen, post #16: Tag your own topic. Two accurate tags do more for how findable it is than a long title, and you can change them later. Go to post

Agreed on all of that, and I have nothing to add to it.

3 likes in reply to #16 17d
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m.ivaturiTL211 Jul 2026#48

Post #46 put the caveat in the right place and I want to underline it.

Trying to state the asking a follow-up position in a way that someone who disagrees would recognise as fair, because I do not think the version in this thread passes that test.

11 likes 17d
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r.chukwuTL212 Jul 2026#49

Careful with the language on asking a follow-up. "Not detected" and "not present" are different findings and the first is a statement about the method.

0 likes 16d
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BramleyTL2Member12 Jul 2026#50

Post #46 describes the usual case. This is about the unusual one.

A photograph of a vial is rarely useful and a photograph of a document usually is. Redact the identifiers before you post either.

1 like 15d
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titration_diaryTL3Regular13 Jul 2026#51
r.chukwu, post #49: Careful with the language on asking a follow-up. "Not detected" and "not present" are different findings and the first is a statement about the method. Go to post

If you are asking about a document, quote the exact wording of the line you are asking about. Paraphrasing a specification is how a discussion ends up about a document nobody has read.

The interesting part of this is the exception, and I do not understand the exception.

16 likes in reply to #49 15d
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h.falkTL214 Jul 2026#52
k.batista, post #39: Post #35 and I disagree about the size of the effect, not about the direction. Asking a follow-up: new topic or reply in the old one? If the answer depends on the previous post, reply. If it is a question that makes sense without the previous post, new topic. The second gets faster answers. Worth saying I have only my own numbers here,… Go to post

Adding the measurement that post #49 says would settle it.

It is fine to say you cannot explain why you are asking. Nobody will press, and the technical part of the question can usually be answered without the context.

6 likes in reply to #39 14d
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e.ferreiraTL3Regular14 Jul 2026#53

Useful. I have added it to my own notes with the date on it.

1 like 14d
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t.duarteTL215 Jul 2026#54

A photograph of a vial is rarely useful and a photograph of a document usually is. Redact the identifiers before you post either.

It is one reading of the data and not the only reasonable one.

0 likes 13d
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dr_bhattacharyaTL3Physician16 Jul 2026#55
g.haaland, post #5: Taking post #4 at face value and following it one step further. If you are asking about a document, quote the exact wording of the line you are asking about. Paraphrasing a specification is how a discussion ends up about a document nobody has read. I have deliberately not rounded that, because the rounding is where the argument starts. Go to post

Answering the question post #54 raises rather than the one it answers.

A question about somebody else's post should be a reply to that post, not a new topic. A question the post happened to raise should be a new topic linking back to it. The difference is whether the answer is useful without the original.

22 likes in reply to #5 12d
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r.erdoganTL216 Jul 2026#56
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lc_gradientTL3Analytical chemist17 Jul 2026#57

A photograph of a vial is rarely useful and a photograph of a document usually is. Redact the identifiers before you post either.

A modest claim, modestly supported.

3 likes 11d
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s.okaforTL217 Jul 2026#58

Something worth flagging about asking a follow-up: the strongest-sounding claims in this thread are the ones with no source attached, which is the usual pattern and not a coincidence.

0 likes 11d
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r.aldana_pharmdTL4Pharmacist18 Jul 2026#59
np_gilmore, post #11: Noted, and thank you for writing it out rather than summarising it. Go to post

If you are new and reading this thread for the answer to asking a follow-up: the answer is conditional, the conditions are in the third reply, and the rest of the thread is worth skipping.

30 likes in reply to #11 10d
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e.vargaTL219 Jul 2026#60

Asking a follow-up: new topic or reply in the old one? If the answer depends on the previous post, reply. If it is a question that makes sense without the previous post, new topic. The second gets faster answers.

I am aware this is the third time this month I have made this point.

15 likes 9d