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Practice · Side effects · continued

Constipation management, with a dietitian's contribution posts 31–60

This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1 · go to the accepted answer.

JV
j.vandermolenTL3Regular18 Feb 2026#31

Helpful, and easy to find again, which is half of what a good reply is.

2 likes 5mo
BC
b.correiaTL221 Feb 2026#32
TN
t.nardoneTL3Regular23 Feb 2026#33

The relationship between symptom burden and outcome is not what people assume. Feeling worse is not evidence of a larger effect and feeling nothing is not evidence of an inactive preparation.

A partial answer, offered because a partial answer beats none.

21 likes 5mo
IA
i.amankwahTL226 Feb 2026 · edited#34
d.szymanski, post #5: The relationship between symptom burden and outcome is not what people assume. Feeling worse is not evidence of a larger effect and feeling nothing is not evidence of an inactive preparation. Go to post

The bit of constipation management that nobody enjoys is that the answer changes depending on what you are trying to decide with it. Say what the decision is and the thread will converge.

9 likes in reply to #5 5mo
H
HHidalgoTL2Member1 Mar 2026#35

I had written a reply contradicting post #33 and deleted it. Here is what survived.

The documentation on constipation management is better than this thread and I say that as someone who has posted in the thread.

0 likes 5mo
ST
s.teixeiraTL23 Mar 2026#36

Confirming post #35 from a second method, which matters more than confirming it from a second person.

The published rates come from populations that were titrated on a defined schedule with clinical supervision. Rates from a forum are not comparable and are biased by who chooses to post.

0 likes 5mo
GV
g.valckenaereTL3Regular6 Mar 2026#37

Where the constipation management discussion usually stalls is that nobody wants to say "I do not know" and everyone is willing to say "it varies". Those are the same sentence with different clothes on.

14 likes 5mo
SD
st.dialloTL29 Mar 2026#38
sterile_file, post #1: Posting this under the heading it deserves: Constipation management, with a dietitian's contribution Everything below is what sits behind that. Constipation management: setting out the arithmetic in full, because I have had to do it twice and I would rather nobody else did. Every step is shown. If the answer is wrong the error will be… Go to post

The relationship between symptom burden and outcome is not what people assume. Feeling worse is not evidence of a larger effect and feeling nothing is not evidence of an inactive preparation.

It cost nothing to check and would have cost something not to.

5 likes in reply to #1 5mo
DS
d.szymanskiTL311 Mar 2026#39
MM
m.mwangiTL214 Mar 2026#40

That is clearer than the version I had in my head. Thank you.

2 likes 4mo
FS
f.sjobergTL216 Mar 2026#41
t.nardone, post #33: The relationship between symptom burden and outcome is not what people assume. Feeling worse is not evidence of a larger effect and feeling nothing is not evidence of an inactive preparation. A partial answer, offered because a partial answer beats none. Go to post

The reason constipation management is hard to answer is that the obvious measurement and the relevant quantity are not the same thing, and substituting one for the other is silent.

4 likes in reply to #33 4mo
DO
dr_okonkwoTL4 Moderator19 Mar 2026#42
st.diallo, post #2: The most useful reply I ever got about constipation management was a request to state my units. It sounds like pedantry and it has saved me twice. Go to post

The published rates come from populations that were titrated on a defined schedule with clinical supervision. Rates from a forum are not comparable and are biased by who chooses to post.

12 likes in reply to #2 4mo
MP
m.perrinTL222 Mar 2026#43

The arithmetic in post #41 is right; the assumption feeding it is the part to check.

An observation about constipation management that I cannot explain and am posting anyway, on the principle that unexplained observations are more useful public than private.

25 likes 4mo
SK
s.karlsen_rphTL3Pharmacist24 Mar 2026#44

The relationship between symptom burden and outcome is not what people assume. Feeling worse is not evidence of a larger effect and feeling nothing is not evidence of an inactive preparation.

On balance I think that is right, and I would not bet much on it.

0 likes 4mo
NB
n.brobergTL227 Mar 2026#45

The published rates come from populations that were titrated on a defined schedule with clinical supervision. Rates from a forum are not comparable and are biased by who chooses to post.

Genuinely open to being wrong about this one.

1 like 4mo
OO
orbitrap_olaTL3Mass spectrometrist29 Mar 2026 · edited#46
dr_okonkwo, post #42: The published rates come from populations that were titrated on a defined schedule with clinical supervision. Rates from a forum are not comparable and are biased by who chooses to post. Go to post

Recognition and grading: nausea ranges from "noticeable" to "limiting". Constipation ranges from mild to severe. Having language to describe the magnitude helps you track whether something is worsening or stable and helps your clinician understand what you are reporting.

7 likes in reply to #42 4mo
IA
i.almeidaTL21 Apr 2026#47

Narrowing post #44, because the general version has more than one answer.

Constipation management has a well-known answer and a correct answer, and the interesting work is establishing that they are the same. Nobody has done that here yet.

18 likes 4mo
DS
dr_seongTL3Physician3 Apr 2026#48

Everything in post #46 holds. The case it does not cover is the one I have.

Adding what did not work for me on constipation management, since the failures never get written up and they are half the useful information.

0 likes 4mo
AW
a.westergaardTL3Regular6 Apr 2026#49
sterile_file, post #1: Posting this under the heading it deserves: Constipation management, with a dietitian's contribution Everything below is what sits behind that. Constipation management: setting out the arithmetic in full, because I have had to do it twice and I would rather nobody else did. Every step is shown. If the answer is wrong the error will be… Go to post

Taking post #48 at face value and following it one step further.

The relationship between symptom burden and outcome is not what people assume. Feeling worse is not evidence of a larger effect and feeling nothing is not evidence of an inactive preparation.

Written quickly, so the reasoning may be tighter than the wording.

0 likes in reply to #1 4mo
DY
d.yilmazTL28 Apr 2026#50

Noted, and I have changed what I was going to do on the strength of it.

4 likes 4mo
II
i.ilungaTL211 Apr 2026#51

Adding the boring version of constipation management, because the interesting version keeps getting posted and the boring one is usually right.

Check the ordinary explanations, in order, and stop when one of them accounts for what you are seeing. Most of the time the second one does.

1 like 4mo
SL
sleep_logTL2Regular13 Apr 2026#52

Before the thread moves on from constipation management — what is the sample size behind the claim? I am not being difficult; I have seen the same figure quoted from an n of four and from an n of four hundred.

0 likes 3mo
LV
l.vukovicTL215 Apr 2026#53

Where I part company with post #49, and it is a narrow parting.

The published rates come from populations that were titrated on a defined schedule with clinical supervision. Rates from a forum are not comparable and are biased by who chooses to post.

I am reporting what happened, not recommending it.

23 likes 3mo
WP
weekly_pinTL2Regular18 Apr 2026#54
sterile_file, post #1: Posting this under the heading it deserves: Constipation management, with a dietitian's contribution Everything below is what sits behind that. Constipation management: setting out the arithmetic in full, because I have had to do it twice and I would rather nobody else did. Every step is shown. If the answer is wrong the error will be… Go to post

Post #53 is the version of this I will quote in future. One addition.

The confident answers on constipation management and the well-sourced answers are not the same answers, which is the most useful thing I have learned reading this category.

11 likes in reply to #1 3mo
WV
w.verhoevenTL220 Apr 2026#55
j.vandermolen, post #31: Helpful, and easy to find again, which is half of what a good reply is. Go to post

Post #53 describes the usual case. This is about the unusual one.

Small correction to my own earlier position on constipation management. I had the units the wrong way round, which changes the conclusion by an order of magnitude and therefore changes it entirely.

0 likes in reply to #31 3mo
SG
s.grigorescuTL2Member23 Apr 2026#56

The relationship between symptom burden and outcome is not what people assume. Feeling worse is not evidence of a larger effect and feeling nothing is not evidence of an inactive preparation.

32 likes 3mo
RW
r.weissTL225 Apr 2026#57

I would put moderate confidence on the mainstream reading of constipation management and no more. That is not scepticism for its own sake; it is where the sourcing actually stops.

17 likes 3mo
IA
i.aranda_esTL2Translator · ES28 Apr 2026#58
sleep_log, post #52: Before the thread moves on from constipation management — what is the sample size behind the claim? I am not being difficult; I have seen the same figure quoted from an n of four and from an n of four hundred. Go to post

Confirming post #57 from a second method, which matters more than confirming it from a second person.

The published rates come from populations that were titrated on a defined schedule with clinical supervision. Rates from a forum are not comparable and are biased by who chooses to post.

That matches what I was told, which is not the same as knowing it.

6 likes in reply to #52 3mo
RE
r.ekstromTL230 Apr 2026#59
sleep_log, post #52: Before the thread moves on from constipation management — what is the sample size behind the claim? I am not being difficult; I have seen the same figure quoted from an n of four and from an n of four hundred. Go to post

On post #57 — agreed on the reasoning, with one qualification.

The relationship between symptom burden and outcome is not what people assume. Feeling worse is not evidence of a larger effect and feeling nothing is not evidence of an inactive preparation.

The short answer was in the first line; everything after is the working.

0 likes in reply to #52 3mo
EF
endo_fellow_rkTL3Endocrinology fellow2 May 2026#60

Thank you for taking the time. That was more work than a reply usually is.

24 likes 3mo