Reports of ordinary results are more valuable than reports of remarkable ones, precisely because only the remarkable ones get posted elsewhere.
I would rather say I do not know than round it up to an answer.
This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1 · go to the accepted answer.
Reports of ordinary results are more valuable than reports of remarkable ones, precisely because only the remarkable ones get posted elsewhere.
I would rather say I do not know than round it up to an answer.
Photograph the vial and the label before opening. It costs ten seconds and it is what turns a report into something checkable.
The conclusion is tentative; the arithmetic underneath it is not.
Dosing and purity: a vial that is 99% pure might contain 80% of its label claim if the other mass is water, counter-ion, and excipient. Purity and content are different. Both matter for different reasons.
It is the kind of thing that is obvious once and never again.
Answering the question post #33 raises rather than the one it answers.
Photograph the vial and the label before opening. It costs ten seconds and it is what turns a report into something checkable.
The arithmetic in post #37 is right; the assumption feeding it is the part to check.
The cost of a submission is worth stating. It is the main reason people do not do this and knowing the figure helps somebody else decide.
Post #37 and I disagree about the size of the effect, not about the direction.
Reports of ordinary results are more valuable than reports of remarkable ones, precisely because only the remarkable ones get posted elsewhere.
I had written a reply contradicting post #40 and deleted it. Here is what survived.
The cost of a submission is worth stating. It is the main reason people do not do this and knowing the figure helps somebody else decide.
Picking up post #42: that is the part I would want checked first.
Blind submission is worth the effort: have someone else relabel the sample so neither you nor the laboratory knows which supplier it came from until the result is back. Blind results change minds; self-selected results do not.
Dosing and purity: a vial that is 99% pure might contain 80% of its label claim if the other mass is water, counter-ion, and excipient. Purity and content are different. Both matter for different reasons.
Post #42 is right about the mechanism and I think understates the practical bit.
Photograph the vial and the label before opening. It costs ten seconds and it is what turns a report into something checkable.
Date the report: when the analysis was done matters. Material can degrade in storage. A report from two years ago is still useful but is not evidence about the current state of the same supplier's stock.
I have separated what I observed from what I concluded, which does not always happen.
Following, with nothing to contribute beyond having asked the same thing elsewhere.
Pattern across lots: a single result is a data point. Three or four results from the same supplier showing a consistent pattern becomes a record worth discussing. Two results that disagree might just be measurement variation.
Photograph the vial and the label before opening. It costs ten seconds and it is what turns a report into something checkable.
The uncertainty is in the assumption, not in the calculation.
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