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Evidence · Journal club

Journal club: what we got wrong in an earlier session

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n.achebeTL211 Jun 2026#1

On the subject in the title: Journal club: what we got wrong in an earlier session Working notes rather than a conclusion.

Bringing a claim rather than a paper, because the claim is the thing circulating.

The statement gets made confidently and cites SURMOUNT-1 (N Engl J Med, 2022) when pressed. I have read the trial and I cannot find the sentence it is supposed to rest on.

Either I am reading the wrong section or the claim has drifted from the source. I would like to know which before I repeat the correction anywhere.

13 likes 2mo
FP
f.piresTL212 Jun 2026#2

Sessions on negative or null results are consistently the most instructive and the hardest to get anyone to attend.

17 likes 2mo
AL
aliquot_lineTL3Regular13 Jun 2026 · edited#3
f.pires, post #2: Sessions on negative or null results are consistently the most instructive and the hardest to get anyone to attend. Go to post

Building on post #2 rather than restating it.

The baseline characteristics table is the single most useful page for the questions that get asked here, because it tells you who the result applies to.

Not disagreeing with anyone above, just adding the bit I keep having to look up.

32 likes in reply to #2 1mo
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v.stanescuTL214 Jun 2026#4
aliquot_line, post #3: Building on post #2 rather than restating it. The baseline characteristics table is the single most useful page for the questions that get asked here, because it tells you who the result applies to. Not disagreeing with anyone above, just adding the bit I keep having to look up. Go to post

Grateful for the specificity. Vague answers to this question are what sent me looking.

0 likes in reply to #3 1mo
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fr.translation_moTL2Translator · FR14 Jun 2026#5

The most common failure mode is spending fifty minutes on the effect size and ten on the population. Reversing that ratio would improve most sessions.

3 likes 1mo
EN
e.nilsenTL215 Jun 2026#6

Answering the question post #5 raises rather than the one it answers.

A conflict-of-interest statement is worth reading aloud and is worth very little as a predictor. Design quality is what to spend the session on.

I have kept the units in throughout, for the obvious reason.

11 likes 1mo
MH
m.haddadTL2Regular15 Jun 2026#7

Reading a preprint in a session is fine provided the status is stated in the first minute and stays in the summary.

That is a description of practice, not a recommendation of it.

24 likes 1mo
KM
k.marchandTL216 Jun 2026#8
m.haddad, post #7: Reading a preprint in a session is fine provided the status is stated in the first minute and stays in the summary. That is a description of practice, not a recommendation of it. Go to post

Reading order that works for these sessions: registry entry, methods, baseline table, primary result, then abstract last. Reading the abstract first anchors everything that follows.

0 likes in reply to #7 1mo
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l.ibarraTL2Regular17 Jun 2026#9

Sensible. I would want the same detail before I acted on it either.

16 likes 1mo
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a.delgadoTL217 Jun 2026#10

Post #8 describes the usual case. This is about the unusual one.

Where the group cannot agree, record the disagreement rather than resolving it by seniority. The recorded disagreement is more honest and more useful later.

Posting it because the silence on this was starting to look like agreement.

31 likes 1mo
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GEldridgeTL3Regular18 Jun 2026#11
k.marchand, post #8: Reading order that works for these sessions: registry entry, methods, baseline table, primary result, then abstract last. Reading the abstract first anchors everything that follows. Go to post

Post #7 describes the usual case. This is about the unusual one.

Bringing the previous paper on the same question makes the session much better and doubles the preparation. Worth doing every third session rather than every one.

19 likes in reply to #8 1mo
AK
a.krastevTL218 Jun 2026 · edited#12

The figures usually contain the finding and the text usually contains the interpretation. Separating them for the first twenty minutes is a discipline worth keeping.

8 likes 1mo
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glossary_deskTL3Regular19 Jun 2026#13

Where the group cannot agree, record the disagreement rather than resolving it by seniority. The recorded disagreement is more honest and more useful later.

I would put this at better than even and not much better.

0 likes 1mo
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a.vestergaardTL219 Jun 2026#14

The baseline characteristics table is the single most useful page for the questions that get asked here, because it tells you who the result applies to.

Old habit: I write down the expected answer before I calculate it.

0 likes 1mo
KB
k.brandl_deTL319 Jun 2026#15
AT
a.teixeiraTL220 Jun 2026#16

Picking up post #14: that is the part I would want checked first.

Nothing discussed in a session is advice to anybody, and clinician participants here say so themselves as a matter of course rather than because a rule requires it.

12 likes 1mo
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aliquot_lineTL3Regular20 Jun 2026#17

Sessions on negative or null results are consistently the most instructive and the hardest to get anyone to attend.

2 likes 1mo
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e.nilsenTL221 Jun 2026#18

The most common failure mode is spending fifty minutes on the effect size and ten on the population. Reversing that ratio would improve most sessions.

0 likes 1mo
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l.ibarraTL2Regular21 Jun 2026 · edited#19

Reading order that works for these sessions: registry entry, methods, baseline table, primary result, then abstract last. Reading the abstract first anchors everything that follows.

Reading it again, the caveat matters more than the finding.

0 likes 1mo
AK
a.kirchnerTL222 Jun 2026#20

This follows post #19 rather than contradicting it.

The baseline characteristics table is the single most useful page for the questions that get asked here, because it tells you who the result applies to.

I have left out the parts I could not verify.

18 likes 1mo
MN
ma.nascimentoTL222 Jun 2026#21
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l.parkinsonTL2Member23 Jun 2026#22
e.nilsen, post #18: The most common failure mode is spending fifty minutes on the effect size and ten on the population. Reversing that ratio would improve most sessions. Go to post

Where the group cannot agree, record the disagreement rather than resolving it by seniority. The recorded disagreement is more honest and more useful later.

It is one reading of the data and not the only reasonable one.

15 likes in reply to #18 1mo
SD
s.demirTL223 Jun 2026#23

Picking up post #20: that is the part I would want checked first.

The most common failure mode is spending fifty minutes on the effect size and ten on the population. Reversing that ratio would improve most sessions.

Small point, but it is the one that usually catches people.

30 likes 1mo
OP
o.pasqualeTL1Member23 Jun 2026#24

On post #22 — agreed on the reasoning, with one qualification.

Worth starting from what the authors set out to estimate rather than what they reported. Half the disagreements in a session dissolve once that is stated explicitly.

Worth one more sentence than it usually gets.

0 likes 1mo
ZS
z.szaboTL224 Jun 2026 · edited#25
aliquot_line, post #17: Sessions on negative or null results are consistently the most instructive and the hardest to get anyone to attend. Go to post

The figures usually contain the finding and the text usually contains the interpretation. Separating them for the first twenty minutes is a discipline worth keeping.

3 likes in reply to #17 1mo
KR
k.redgraveTL2Member24 Jun 2026#26

Sessions on negative or null results are consistently the most instructive and the hardest to get anyone to attend.

10 likes 1mo
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s.ivaturiTL225 Jun 2026#27

Adding the measurement that post #24 says would settle it.

The baseline characteristics table is the single most useful page for the questions that get asked here, because it tells you who the result applies to.

A modest claim, modestly supported.

22 likes 1mo
CP
citation_peakTL3Regular25 Jun 2026#28

Where the group cannot agree, record the disagreement rather than resolving it by seniority. The recorded disagreement is more honest and more useful later.

If that reads as pedantic, it is, and it has saved me twice.

0 likes 1mo
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p.onwukaTL225 Jun 2026#29

Narrowing post #28, because the general version has more than one answer.

Session format: read the paper before posting. The discussion is much better when everyone has. Start with the estimand and population, then methods, then results, then limitations. That order makes critique coherent.

1 like 1mo
LA
l.aaltonenTL3Regular26 Jun 2026#30
e.nilsen, post #18: The most common failure mode is spending fifty minutes on the effect size and ten on the population. Reversing that ratio would improve most sessions. Go to post

Noted, and I have changed what I was going to do on the strength of it.

6 likes in reply to #18 1mo