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Sourcing · Independent verification · continued

Publishing an inconvenient result: a case study posts 61–71

This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1.

CD
cohort_driftTL3Regular5 Aug 2025 · edited#61

That is the distinction I keep failing to hold on to. Written down now.

2 likes 12mo
TV
to.vargaTL27 Aug 2025#62

Marking my uncertainty on publishing an inconvenient result explicitly. I am confident about the direction, much less confident about the size, and not confident at all that it generalises past the case in the first post.

9 likes 12mo
GH
g.haalandTL3Regular9 Aug 2025#63
Wendelboe, post #6: Everything in post #4 holds. The case it does not cover is the one I have. The most useful reply I ever got about publishing an inconvenient result was a request to state my units. It sounds like pedantry and it has saved me twice. Go to post

Picking up post #60: that is the part I would want checked first.

Repeat determination on the same product line months apart is the measurement that speaks to consistency, and consistency is what most buyers actually want.

Caveat: everything above assumes the paperwork is what it says it is.

21 likes in reply to #6 12mo
SB
s.beaulieuTL211 Aug 2025#64
BP
bench_peakTL3Regular12 Aug 2025#65

Where two services agree with each other and with the declared figure, that is a genuinely strong result and it applies to that lot.

1 like 11mo
SO
s.oyelaranTL214 Aug 2025#66

I had written a reply contradicting post #62 and deleted it. Here is what survived.

Reading back through the publishing an inconvenient result threads from last year, the same three questions come up every time and only one of them has ever been answered properly. That seems like a documentation gap rather than a knowledge gap.

6 likes 11mo
O
OTeixeiraTL3Regular16 Aug 2025#67
p.novotny, post #14: Blind sampling: submitting without the laboratory or seller knowing the source removes the two easiest ways for a result to be shaped: selective submission and selective reporting. The extra effort is worth it. Go to post

Nobody has said the unglamorous part of publishing an inconvenient result yet, so: most of the variation is explained by things that are boring to write about and easy to check.

15 likes in reply to #14 11mo
SO
s.okonkwoTL218 Aug 2025#68

Repeat testing: if you want to verify the same lot a second time, testing with a different service strengthens the conclusion. Testing with the same service verifies reproducibility but uses the same method.

30 likes 11mo
SD
s.duarteTL220 Aug 2025#69
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v.bhattacharyaTL221 Aug 2025 · edited#70
glossary_desk, post #46: Interpreting a result: a purity figure is one measurement on one vial on one day. Agreement across two services is much stronger. A single high number does not establish a pattern. Reporting the observation and leaving the explanation open deliberately. Go to post

Where I part company with post #66, and it is a narrow parting.

Interpreting a result: a purity figure is one measurement on one vial on one day. Agreement across two services is much stronger. A single high number does not establish a pattern.

The part I am sure of is shorter than the part I have written.

3 likes in reply to #46 11mo
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s.cabreraTL223 Aug 2025#71

Post #70 describes the usual case. This is about the unusual one.

If someone has run publishing an inconvenient result properly I would rather read that than my own reconstruction of it. Posting mine only because the thread has gone quiet.

0 likes 11mo

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