Nothing in this subcategory is medical advice and none of it is a substitute for a demonstration from somebody qualified to give one, which most prescribers will do without being asked twice.
29 likes 21d
Practice · Administration · continued
Rotating between abdomen, thigh and upper arm: absorption differences — one year on posts 91–103
This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1.
I keep a log for Rotating between abdomen specifically because my memory of it turned out to be systematically wrong in one direction. Six weeks of notes cost nothing and settled it.
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taper_table, post #20: Nothing in this subcategory is medical advice and none of it is a substitute for a demonstration from somebody qualified to give one, which most prescribers will do without being asked twice. That is where I would start, not where I would stop. Go to post
Post #90 and I disagree about the size of the effect, not about the direction.
If you have to inject at a different time of day than usual, that is a much smaller perturbation than it feels for a weekly compound with a week-long half-life.
Adding it because I spent an afternoon working it out and nobody should have to twice.
Where I have landed on Rotating between abdomen, having got it wrong once in public: the direction is clear, the magnitude is not, and anyone quoting a precise magnitude has borrowed it from somewhere that did not measure it.
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Subcutaneous injection into abdominal tissue, thigh or upper arm is what the licensed labelling in this class describes, and the published comparisons found the differences in exposure between those sites small.
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a.hartmann, post #10: Subcutaneous injection into abdominal tissue, thigh or upper arm is what the licensed labelling in this class describes, and the published comparisons found the differences in exposure between those sites small. Go to post
Grateful for the specificity. Vague answers to this question are what sent me looking.
The arithmetic in post #96 is right; the assumption feeding it is the part to check.
What would change my mind on Rotating between abdomen is a second dataset collected by someone with no stake in the first. Until then I hold it loosely and I would rather say so than pretend to more.
15 likes 7d
Collapsed as off-topic by two members at trust level 3 or above
Answering the question post #99 raises rather than the one it answers.
If you have to inject at a different time of day than usual, that is a much smaller perturbation than it feels for a weekly compound with a week-long half-life.
j.vandermolen, post #7: On post #3 — agreed on the reasoning, with one qualification. If you have to inject at a different time of day than usual, that is a much smaller perturbation than it feels for a weekly compound with a week-long half-life. Go to post
Bleeding at the injection site: normal and usually minimal. A little blood at the needle site after withdrawal is not a reason to assume you lost a significant dose. The needle passed through tissue and there is a small amount of bleeding in the tract.
Building on post #102 rather than restating it.
A site rotation scheme that actually works: abdomen, outer thigh, back of arm, outer hip. Rotate through them in order, move a minimum 2 cm between consecutive sites, note the site with each dose. If a local reaction appears you have the history. If you rotate properly you will not get lipohypertrophy from overuse of one area.
A weak preference rather than a position.
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