The Peptide CommonsEst. May 2024
Independent. We sell nothing and are affiliated with no manufacturer or pharmacy. Every moderation action is logged in public
Access · Shortages · continued

Second pass at: Hoarding and why it makes a shortage worse posts 61–90

This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1.

KB
k.bettencourtTL2Member11 Oct 2024 · edited#61
m.strand_rph, post #47: Reports that a pharmacy has stock are the least durable information on the site and are still worth posting with a date. A qualification I should have led with rather than closed on. Go to post

Shortage-driven price movement is real and is a separate question from availability.

12 likes in reply to #47 22mo
TB
t.brandtTL211 Oct 2024#62

The published shortage register maintained by the national regulator is the authoritative source here, and it is updated far more often than any thread.

4 likes 22mo
L
LundqvistTL2Member11 Oct 2024#63

Shortage predictions: regulators and suppliers issue shortage alerts before they become acute. Checking the regulatory website for shortages gives you advance notice.

I would put this at better than even and not much better.

0 likes 22mo
JS
j.solbergTL211 Oct 2024#64

Post #61 is right about the mechanism and I think understates the practical bit.

Reports that a pharmacy has stock are the least durable information on the site and are still worth posting with a date.

Old habit: I write down the expected answer before I calculate it.

0 likes 22mo
SE
septum_entryTL2Member11 Oct 2024#65
e.pires, post #43: Dose hold versus tapering: if a temporary shortage forces a gap, holding your dose and resuming when supply returns is different from gradually tapering. The two are different decisions. Go to post

On post #61 — agreed on the reasoning, with one qualification.

International supply chains: a shortage in one country does not mean shortage in another. That is why ordering from multiple suppliers before a shortage gets bad is prudent if you can.

I have said this before in a thread nobody could find, so it is worth repeating.

8 likes in reply to #43 22mo
FL
f.laurentTL211 Oct 2024#66

Managing an unplanned gap: if a shortage causes a gap in treatment, the questions are how long the gap will be and how that affects your condition. Discussing with your clinician is prudent if the gap is weeks or longer.

2 likes 22mo
AT
apostille_traceTL1Member11 Oct 2024#67

Nothing to add, except that this is the answer I would give if asked.

0 likes 22mo
CF
c.falkTL211 Oct 2024#68
a.zamora, post #60: Noted, and thank you for writing it out rather than summarising it. Go to post

Shortage-driven price movement is real and is a separate question from availability.

Posted with less confidence than the sentence structure implies.

25 likes in reply to #60 22mo
D
DKwiatkowskiTL3Regular11 Oct 2024#69

Post #65 put the caveat in the right place and I want to underline it.

Compounding during shortages: some jurisdictions allow pharmacy compounding when a marketed product is in shortage. That permission is jurisdiction-specific and time-limited (usually for the duration of the shortage).

Reporting the observation and leaving the explanation open deliberately.

24 likes 22mo
LK
l.krastevTL211 Oct 2024 · edited#70

Building on post #69 rather than restating it.

Anyone reporting availability should say the region and the date, because both determine whether the report is usable.

If that is already documented somewhere, ignore me and link it.

11 likes 22mo
BJ
b.jankowiakTL3Regular11 Oct 2024#71
Ziegler, post #52: Both are useful and different. The notice tells you the national position; the account tells you what is happening on the ground. If anyone has run this properly I would rather read that than my own guess. Go to post

Right, and stated more narrowly than I would have dared to state it.

19 likes in reply to #52 22mo
PD
p.dialloTL211 Oct 2024#72
DKwiatkowski, post #69: Post #65 put the caveat in the right place and I want to underline it. Compounding during shortages: some jurisdictions allow pharmacy compounding when a marketed product is in shortage. That permission is jurisdiction-specific and time-limited (usually for the duration of the shortage). Reporting the observation and leaving the… Go to post

Reports that a pharmacy has stock are the least durable information on the site and are still worth posting with a date.

0 likes in reply to #69 22mo
YM
y.mensahTL3Wiki editor11 Oct 2024#73

Post #72 answers the question as asked. The question underneath it is different.

A shortage of one presentation is not a shortage of all of them, and the published notices are specific about which.

Not a strong opinion, just a consistent one.

0 likes 22mo
RM
r.mensahTL211 Oct 2024#74

I read post #70 twice before replying, because I had assumed the opposite.

Switching presentation or strength during a shortage is a prescribing decision rather than a substitution anybody should improvise.

That is the shape of it. The detail is where I would expect to be corrected.

4 likes 22mo
NE
n.ekstromTL2Regular12 Oct 2024 · edited#75
Lundqvist, post #63: Shortage predictions: regulators and suppliers issue shortage alerts before they become acute. Checking the regulatory website for shortages gives you advance notice. I would put this at better than even and not much better. Go to post

Where an alternative within the class is available, the comparison is a clinical one and the doses are not equivalent.

Two people can read the same figure differently here and both be reasonable.

13 likes in reply to #63 22mo
CC
c.castellanosTL212 Oct 2024#76

On post #74 — agreed on the reasoning, with one qualification.

Both are useful and different. The notice tells you the national position; the account tells you what is happening on the ground.

Noting that the question and the thing people usually mean by it are different.

27 likes 22mo
SS
steady_stateTL3Regular12 Oct 2024#77

Post #76 is right about the mechanism and I think understates the practical bit.

Pharmacy-level availability varies enormously during a shortage, so two honest accounts from the same city can be opposite.

Written quickly, so the reasoning may be tighter than the wording.

0 likes 22mo
TK
t.karlsenTL212 Oct 2024#78

Both are useful and different. The notice tells you the national position; the account tells you what is happening on the ground.

I have written this out at length because the short version keeps being misread.

2 likes 22mo
ED
e.dalgleishTL3Regular12 Oct 2024#79
r.mensah, post #74: I read post #70 twice before replying, because I had assumed the opposite. Switching presentation or strength during a shortage is a prescribing decision rather than a substitution anybody should improvise. That is the shape of it. The detail is where I would expect to be corrected. Go to post

Building on post #76 rather than restating it.

Regional differences during a shortage are large, and a supply position in one country says nothing about another.

I would call that likely rather than established.

0 likes in reply to #74 22mo
BT
b.teixeiraTL212 Oct 2024#80

This is the answer, and the reason it is the answer is the more useful part.

0 likes 22mo
SK
s.kravchenkoTL212 Oct 2024#81
EL
endpoint_lineTL3Regular12 Oct 2024#82
TL4_Halvorsen, post #22: Building on post #21 rather than restating it. Shortage-driven price movement is real and is a separate question from availability. The step people skip is the one I have spelled out. Go to post

Shortage-driven price movement is real and is a separate question from availability.

4 likes in reply to #22 22mo
ZA
z.adeyemiTL212 Oct 2024#83

Right — I had this wrong and I am glad to have read it before it mattered.

0 likes 22mo
R
RidgewayTL3Regular12 Oct 2024#84

Picking up post #82: that is the part I would want checked first.

Where a shortage forces a gap, the pharmacokinetics mean a missed week is a perturbation rather than a reset, which is worth knowing.

The honest answer is that it depends, and here is what it depends on.

26 likes 22mo
IG
i.grimaldiTL212 Oct 2024#85

Coming back to post #84, because the follow-up matters more than the original answer.

Reports that a pharmacy has stock are the least durable information on the site and are still worth posting with a date.

I looked this up rather than remembered it, which is the right order.

8 likes 22mo
EF
erratum_fileTL3Regular12 Oct 2024#86
h.lindqvist, post #14: Where I part company with post #12, and it is a narrow parting. Shortage predictions: regulators and suppliers issue shortage alerts before they become acute. Checking the regulatory website for shortages gives you advance notice. Worth one more sentence than it usually gets. Go to post

Post #84 is right about the mechanism and I think understates the practical bit.

Manufacturer allocation decisions during a shortage are commercial and are rarely explained, which is frustrating and is not evidence of anything.

That is where I would start, not where I would stop.

2 likes in reply to #14 22mo
HJ
h.jansenTL212 Oct 2024 · edited#87

Planning around a known shortage window is easier than reacting to one, and the notices give advance warning more often than people expect.

0 likes 22mo
G
GEldridgeTL3Regular12 Oct 2024#88

Supply interruptions: official shortage notices are published by regulatory agencies. That is the correct primary source rather than pharmacy rumors or forum discussion.

The general case is well covered; this is the awkward specific one.

19 likes 22mo
GV
g.verhoevenTL212 Oct 2024#89

Planning around a known shortage window is easier than reacting to one, and the notices give advance warning more often than people expect.

It is the sort of thing that seems obvious in retrospect and was not at the time.

25 likes 22mo
Z
ZieglerTL312 Oct 2024#90