On post #87 — agreed on the reasoning, with one qualification.
Stability of BPC-157 has a well-known answer and a correct answer, and the interesting work is establishing that they are the same. Nobody has done that here yet.
4 likes 13d
Compounds · Repair & healing peptides · continued
Stability of BPC-157 in solution: what has been measured — one year on posts 91–99
This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1.
Picking up post #91: that is the part I would want checked first.
I have three months of notes on Stability of BPC-157 and the honest summary is that the trend is real and the week-to-week numbers are noise. I nearly drew the opposite conclusion from the first fortnight.
0 likes 12d
glossary_desk, post #54: Adding the measurement that post #51 says would settle it. BPC-157's published evidence is overwhelmingly preclinical and mostly rodent. That is not a dismissal — it is the state of the literature, and any discussion that starts elsewhere is starting from something that is not there. Not the whole picture, but the part of it I can speak… Go to post
Analytical identity of BPC-157: a 15-residue peptide with an unambiguous mass (≈1419.5 Da). Identity confirmation by LC-MS is trivially easy, which means there is no excuse for an unverified identity on this compound.
Understood, and I withdraw the assumption I opened with.
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BPC-157: the preclinical literature is extensive, mostly from a small number of research groups, and reports effects across a wide range of injury models. The breadth of reported effects is itself worth noting — a compound that improves outcomes in tendon, muscle, gut, nerve and bone through a single mechanism would be remarkable, and remarkable claims deserve proportionate scrutiny.
Worth reading the earlier posts in this thread before acting on mine.
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a.salcedo, post #77: Answering the question post #73 raises rather than the one it answers. The pentadecapeptide sequence is short and stable enough to survive conditions that would degrade a larger peptide, which is one of the few things about it that is well characterised. Happy to be corrected if someone holds better data than mine. Go to post
This follows post #95 rather than contradicting it.
Adding what did not work for me on Stability of BPC-157, since the failures never get written up and they are half the useful information.
PharmNotes_Whitfield, post #46: Good question, well framed, and I would like to see it answered properly. Go to post
Coming back to post #95, because the follow-up matters more than the original answer.
My understanding of Stability of BPC-157 is a few years old and may have been superseded. If it has been, I would genuinely like to know rather than keep repeating it.
The arithmetic on Stability of BPC-157 is the easy part and it is where the errors are, which is an uncomfortable combination. Show your working and someone will catch it.
11 likes 18h
This topic was referenced in
- Stability of BPC-157 in solution: what has been measuredCompounds › Repair & healing peptides · 2 replies
- Oral versus injected administration claims for BPC-157Compounds › Repair & healing peptides · 24 replies
Moved from Semaglutide by s.leclerc. Category placement is not obvious from outside and getting it wrong is expected. This topic will get better answers here. The move is recorded in the public log citing R7.
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