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90 topics 27 solved Group: Status

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90 topics · page 1 of 3

Topic	Participants	Replies	Views	Activity
GHRH analogues versus ghrelin mimetics: different mechanisms, conflated discussion Compounds › Secretagogues & GH axis CJC-1295 observational data ipamorelin needs a source Solved On the subject in the title: GHRH analogues versus ghrelin mimetics: different mechanisms, conflated discussion Working notes rather than a conclusion. Asking about GHRH analogues versus ghrelin mimetics…	+47	53	6.9k	2h
A widely repeated interaction claim that turns out to be unsupported — what changed since Practice › Interactions insulin hypoglycaemia metformin needs a source Solved A widely repeated interaction claim that turns out to be unsupported — what changed since Writing it up because I had to work it out twice and would rather nobody else did. I was wrong about widely repeated…	+89	94	5.9k	2h
Reading a rodent study on a secretagogue without over-extrapolating — the long version Compounds › Secretagogues & GH axis observational data tesamorelin ipamorelin needs a source Reading a rodent study on a secretagogue without over-extrapolating — the long version — setting out what I have, and where I think it stops being reliable. A narrow question about Reading a rodent study,…	+59	66	30k	4h
Sulfonylureas: the interaction most worth taking seriously Practice › Interactions needs a source metformin insulin Sulfonylureas: the interaction most worth taking seriously Writing it up because I had to work it out twice and would rather nobody else did. An honest uncertainty about sulfonylureas rather than a disguised…	+4	8	38k	6h
Common supplements people ask about, assessed one at a time Practice › Interactions insulin needs a source hypoglycaemia metformin Common supplements people ask about, assessed one at a time — setting out what I have, and where I think it stops being reliable. A follow-up question about common supplements that I did not know to ask the…	+101	107	28k	12h
[2026 update] Antibiotics and a course of something with delayed emptying Practice › Interactions metformin needs a source delayed gastric emptying insulin On the subject in the title: Antibiotics and a course of something with delayed emptying Working notes rather than a conclusion. Something changed and I would like to know whether it should have. Same…	+88	97	19k	13h
Stability of BPC-157 in solution: what has been measured — one year on Compounds › Repair & healing peptides needs a source observational data preprint BPC-157 On the subject in the title: Stability of BPC-157 in solution: what has been measured — one year on Working notes rather than a conclusion. A narrow question about Stability of BPC-157, deliberately narrow,…	+84	98	7.8k	18h
AOD-9604 and the fragment hypothesis, revisited — does this still hold? Compounds › Other compounds research use only needs a source mislabelling Solved The question in the title: AOD-9604 and the fragment hypothesis, revisited — does this still hold? I will give what I have already checked below so nobody repeats it. What changes if the standard account of…	+7	11	31k	19h
Publication patterns in the BPC-157 literature, examined Compounds › Repair & healing peptides preprint BPC-157 TB-500 needs a source Solved Posting this under the heading it deserves: Publication patterns in the BPC-157 literature, examined Everything below is what sits behind that. Putting the numbers in the first post, because a question about…	+40	45	3.4k	21h
CJC-1295 with and without DAC: what the modification does Compounds › Secretagogues & GH axis needs a source tesamorelin CJC-1295 GHRP class On the subject in the title: CJC-1295 with and without DAC: what the modification does Working notes rather than a conclusion. Putting the numbers in the first post, because a question about a compound…	+117	123	5.6k	22h
What would change my mind about repair peptides: a specific answer Compounds › Repair & healing peptides TB-500 needs a source preprint Under review What would change my mind about repair peptides: a specific answer — that is the question, and I have not found it answered plainly anywhere I have looked. Documentation question rather than a pharmacological…	+26	30	1.1k	23h
BPC-157: what the rodent literature actually shows, and what it does not — does this still hold? Compounds › Repair & healing peptides observational data needs a source BPC-157 TB-500 Solved The question in the title: BPC-157: what the rodent literature actually shows, and what it does not — does this still hold? I will give what I have already checked below so nobody repeats it. I would like to…	+6	10	3.1k	1d
Coming back to: Delayed gastric emptying and oral medication absorption: which drugs matter Practice › Interactions hypoglycaemia metformin insulin needs a source Solved Delayed gastric emptying and oral medication absorption: which drugs matter Writing it up because I had to work it out twice and would rather nobody else did. Reading back through what has been written here…	+63	74	11k	1d
Why the absence of controlled human data on BPC-157 matters more than people admit Compounds › Repair & healing peptides needs a source BPC-157 preprint Solved Why the absence of controlled human data on BPC-157 matters more than people admit — that is the question, and I have not found it answered plainly anywhere I have looked. I would like to know what people…	+60	66	16k	1d
Revisiting: How this community labels and discusses unrefereed work Evidence › Preprints needs a source risk of bias preprint effect size Solved Revisiting: How this community labels and discusses unrefereed work Writing it up because I had to work it out twice and would rather nobody else did. Reading an unrefereed manuscript properly, and asking…	+31	35	7k	1d
Research-use-only status: what it means legally and practically Compounds › Other compounds research use only custom synthesis needs a source mislabelling Research-use-only status: what it means legally and practically Writing it up because I had to work it out twice and would rather nobody else did. Asking about research-use-only status directly, because I…	+72	81	44k	1d
Follow-up: Reading an interaction checker output critically Practice › Interactions insulin hypoglycaemia delayed gastric emptying needs a source Solved Reading an interaction checker output critically — setting out what I have, and where I think it stops being reliable. A follow-up question about Reading an interaction checker output that I did not know to…	+62	66	13k	2d
Why catalogue breadth is not evidence of anything Compounds › Other compounds research use only needs a source custom synthesis Under review Why catalogue breadth is not evidence of anything I have a specific reason for asking rather than idle curiosity, and the context is below. What changes if the standard account of catalogue breadth is wrong?…		2	38k	2d
Evidence quality in the secretagogue literature: an honest assessment Compounds › Secretagogues & GH axis ipamorelin observational data GHRP class tesamorelin Solved Evidence quality in the secretagogue literature: an honest assessment Writing it up because I had to work it out twice and would rather nobody else did. I have spent a fortnight trying to pin evidence quality…		2	25k	9d
Secretagogues and glucose tolerance: the mechanistic concern Compounds › Secretagogues & GH axis CJC-1295 tesamorelin observational data needs a source On the subject in the title: Secretagogues and glucose tolerance: the mechanistic concern Working notes rather than a conclusion. Secretagogues and glucose tolerance, and specifically the version of it that…	+64	70	52k	17d
Second pass at: Metformin co-administration and additive GI effects Practice › Interactions hypoglycaemia delayed gastric emptying metformin needs a source On the subject in the title: Second pass at: Metformin co-administration and additive GI effects Working notes rather than a conclusion. Posting a small dataset on Metformin co-administration. It is mine, it…	+131	142	56k	19d
Why this subcategory is stricter about sourcing than most Compounds › Secretagogues & GH axis observational data tesamorelin needs a source GHRP class Wiki Asking directly, because I could not find a straight answer: Why this subcategory is stricter about sourcing than most A comparison question rather than a question about one compound. Two things in the same…	+48	52	617	21d
Naming conventions for research peptides and the confusion they cause Compounds › Other compounds custom synthesis mislabelling research use only needs a source Posting this under the heading it deserves: Naming conventions for research peptides and the confusion they cause Everything below is what sits behind that. I was wrong about naming conventions for research…	+21	25	4.9k	22d
Stability of BPC-157 in solution: what has been measured Compounds › Repair & healing peptides BPC-157 observational data needs a source TB-500 Stability of BPC-157 in solution: what has been measured — setting out what I have, and where I think it stops being reliable. Something about stability of BPC-157 does not reconcile and I would like a second…		2	805	30d
Analytical identity of BPC-157: a 15-mer with a simple mass — does this still hold? Compounds › Repair & healing peptides needs a source preprint BPC-157 Analytical identity of BPC-157: a 15-mer with a simple mass — does this still hold? — that is the question, and I have not found it answered plainly anywhere I have looked. The question about Analytical…	+28	33	1.6k	1mo
Delayed gastric emptying and oral medication absorption: which drugs matter — one year on Practice › Interactions needs a source delayed gastric emptying hypoglycaemia insulin Solved Closed On the subject in the title: Delayed gastric emptying and oral medication absorption: which drugs matter — one year on Working notes rather than a conclusion. A follow-up question about Delayed gastric…		3	16k	2mo
How this community labels and discusses unrefereed work — the long version Evidence › Preprints needs a source effect size risk of bias Asking directly, because I could not find a straight answer: How this community labels and discusses unrefereed work — the long version Reading an unrefereed manuscript properly, and asking whether I am doing…	+18	23	21k	2mo
Common supplements people ask about, assessed one at a time — a second dataset Practice › Interactions delayed gastric emptying insulin needs a source Posting this under the heading it deserves: Common supplements people ask about, assessed one at a time — a second dataset Everything below is what sits behind that. A follow-up question about Common…	+97	104	15k	3mo
About the Preprints category Evidence › Preprints preprint risk of bias needs a source Pinned Wiki Unrefereed work, clearly labelled as such, with the usual caveats stated once and taken seriously. This post is a community wiki: any member at trust level 3 or above can edit it, and every edit is recorded…	+3	7	14k	3mo
A widely repeated interaction claim that turns out to be unsupported Practice › Interactions metformin hypoglycaemia delayed gastric emptying needs a source On the subject in the title: A widely repeated interaction claim that turns out to be unsupported Working notes rather than a conclusion. I was wrong about widely repeated interaction claim in a thread last…	+47	51	37k	3mo

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