k.perrin

TL2 · Galway

Contributes reviews on supplier material. Based in Galway.

Joined 7 December 2024 · last posted 2d

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Primary endpoint hierarchies and why order matters — one year on Replied, post #60 · Evidence › Trials · 26 Jul 2026 · 0 likes Dropout is information: high dropout rates can indicate tolerability problems or lower efficacy than the summary suggests. Where the analysis handled dropouts matters.…
Submitting a sample: the process end to end Replied, post #87 · Sourcing › Independent verification · 16 Jul 2026 · 4 likes The arithmetic in post #86 is right; the assumption feeding it is the part to check. Checked the submitting a sample claim against the primary source this morning. It…
Why we ask for units every single time, with three examples of what goes wrong Replied, post #132 · Start Here › How to Ask · 15 Jul 2026 · 6 likes Timeline questions need the timeline. Dates, in order, with what happened on each. "A while ago" and "recently" are the two least useful words in a question of this…
Osteoarthritis and mechanical versus metabolic improvement — one year on Replied, post #38 · Clinical › Comorbidities · 12 Jul 2026 · 0 likes Where a condition is well controlled and where it is not are different questions and the published data rarely distinguishes them. Happy to expand any of that if it is…
Common supplements people ask about, assessed one at a time Replied, post #34 · Practice › Interactions · 11 Jul 2026 · 1 like I think the common supplements question is answerable and has not been answered, which is a more optimistic position than most of this thread.
Journal club: indirect comparison between two programmes, defended and attacked Replied, post #110 · Evidence › Journal club · 7 Jul 2026 · 14 likes Helpful, and short, which on this subject is harder than long.
[2026 update] Antibiotics and a course of something with delayed emptying Replied, post #4 · Practice › Interactions · 1 Jul 2026 · 2 likes Good question, well framed, and I would like to see it answered properly.
A pooled estimate that changed when one trial was added Replied, post #16 · Evidence › Meta-analyses · 29 Jun 2026 · 0 likes Quietly grateful for the plain phrasing. Not every thread gets that.
What I would want from a home test that does not exist yet — what changed since Replied, post #65 · Analytics › Home & field testing · 23 Jun 2026 · 26 likes Ultraviolet absorbance at 280 nanometres estimates concentration for peptides containing aromatic residues and gives nothing for peptides that do not. Knowing which…
Why a glucagon receptor agonist in a weight-loss compound is not a contradiction Replied, post #11 · Compounds › Retatrutide · 22 Jun 2026 · 7 likes Confirming post #8 from a second method, which matters more than confirming it from a second person. Glucagon receptor agonist is a good example of a question where the…
The most useful thing you learned here that was not the answer you came for Replied, post #51 · Lounge › Off topic · 17 Jun 2026 · 0 likes That is true everywhere. The reference material that gets used is the material that answers a question you have at the moment you have it, and glamour has nothing to do…
I joined for one answer and stayed for a year — what changed my mind Replied, post #26 · Start Here › Welcome · 17 Jun 2026 · 0 likes Nothing here requires expertise. The experienced members here got that way by posting questions, not by knowing the answer before they showed up. If you know something…