Tags · Evidence
risk of bias
Structured appraisal of internal validity.
Related in this group: STEP programme · SURMOUNT programme · SURPASS programme · SELECT trial · FLOW trial · SOUL trial · TRIUMPH programme · PIONEER programme · SUSTAIN programme · LEADER trial · randomised trial · meta-analysis
83 topics · page 1 of 3
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Journal club: indirect comparison between two programmes, defended and attacked
Journal club: indirect comparison between two programmes, defended and attacked Writing it up because I had to work it out twice and would rather nobody else did. Trying to work out what would count as…
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+122 | 131 | 5.2k | just now |
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Journal club: STEP 1 and the treatment-policy estimand
Journal club: STEP 1 and the treatment-policy estimand Writing it up because I had to work it out twice and would rather nobody else did. Session topic: STEP 1 ( N Engl J Med , 2021). Please read it before…
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3 | 11k | 9h | |
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Journal club: STEP 8 and the fairness of the comparator dose — a second dataset
Posting this under the heading it deserves: Journal club: STEP 8 and the fairness of the comparator dose — a second dataset Everything below is what sits behind that. Posting a small dataset on STEP 8. It is…
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+18 | 22 | 656 | 13h |
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Journal club: semaglutide in MASH, and surrogate endpoints
Posting this under the heading it deserves: Journal club: semaglutide in MASH, and surrogate endpoints Everything below is what sits behind that. Working notes on semaglutide in MASH rather than a conclusion.…
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+24 | 28 | 17k | 15h |
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Journal club: STEP 1 and the treatment-policy estimand — does this still hold?
Asking directly, because I could not find a straight answer: Journal club: STEP 1 and the treatment-policy estimand — does this still hold? Working notes on STEP 1 rather than a conclusion. I would rather…
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+70 | 76 | 4.8k | 15h |
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A critique that turned out to be unfair, retracted by its author
Posting this under the heading it deserves: A critique that turned out to be unfair, retracted by its author Everything below is what sits behind that. Critique, and specifically the version of it that the…
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+34 | 38 | 20k | 17h |
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Coming back to: A structured critique template this community uses
Posting this under the heading it deserves: A structured critique template this community uses Everything below is what sits behind that. Reading back through what has been written here about structured…
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+63 | 69 | 17k | 18h |
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Immortal time bias in a claims-database study — one year on
Posting this under the heading it deserves: Immortal time bias in a claims-database study — one year on Everything below is what sits behind that. I would like to disagree carefully with the settled view on…
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+41 | 46 | 3.7k | 22h |
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Risk-of-bias tools and the judgement they conceal — does this still hold?
Risk-of-bias tools and the judgement they conceal — does this still hold? — that is the question, and I have not found it answered plainly anywhere I have looked. Asking about Risk-of-bias tools on behalf of…
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+26 | 30 | 5.8k | 23h |
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Pooling trials with different estimands
On the subject in the title: Pooling trials with different estimands Working notes rather than a conclusion. Asking about pooling trials with different estimands on behalf of the question I keep seeing asked…
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+120 | 132 | 2.3k | 1d |
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A structured critique template this community uses
A structured critique template this community uses — setting out what I have, and where I think it stops being reliable. Structured critique template — I have the observation and I do not trust my…
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2 | 18k | 1d | |
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Selection into a registry and what it does to the estimate — a second dataset
Posting this under the heading it deserves: Selection into a registry and what it does to the estimate — a second dataset Everything below is what sits behind that. Posting a small dataset on Selection. It is…
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+28 | 32 | 1.3k | 1d |
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Revisiting: How this community labels and discusses unrefereed work
Revisiting: How this community labels and discusses unrefereed work Writing it up because I had to work it out twice and would rather nobody else did. Reading an unrefereed manuscript properly, and asking…
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+31 | 35 | 7k | 1d |
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Journal club: SUSTAIN 6 and its retinopathy signal
On the subject in the title: Journal club: SUSTAIN 6 and its retinopathy signal Working notes rather than a conclusion. Reading SUSTAIN 6 ( N Engl J Med , 2016) for the population rather than the effect,…
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+110 | 122 | 46k | 1d |
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Coming back to: Why a preprint's supplementary material is often the best part
Why a preprint's supplementary material is often the best part — that is the question, and I have not found it answered plainly anywhere I have looked. A question about how this site should cite something…
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+109 | 116 | 36k | 2d |
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Revisiting: Journal club: SURMOUNT-OSA and a hard endpoint in a soft field
Revisiting: Journal club: SURMOUNT-OSA and a hard endpoint in a soft field — setting out what I have, and where I think it stops being reliable. Collecting what is known about SURMOUNT-OSA in one place,…
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+108 | 122 | 52k | 7d |
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Revisiting: Journal club: SURMOUNT-1, read without the press release
On the subject in the title: Revisiting: Journal club: SURMOUNT-1, read without the press release Working notes rather than a conclusion. Session topic: SURMOUNT-1 ( N Engl J Med , 2022). Please read it…
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+54 | 62 | 1.5k | 26d |
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Journal club: STEP 3 and the intensive behavioural therapy floor
Posting this under the heading it deserves: Journal club: STEP 3 and the intensive behavioural therapy floor Everything below is what sits behind that. Two things I would like separated before anyone answers…
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+6 | 10 | 13k | 28d |
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Second pass at: A pooled estimate that changed when one trial was added
On the subject in the title: Second pass at: A pooled estimate that changed when one trial was added Working notes rather than a conclusion. Two things I would like separated before anyone answers on pooled…
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+26 | 30 | 22k | 1mo |
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Journal club: SELECT, absolute risk, and how it was reported — a second dataset
On the subject in the title: Journal club: SELECT, absolute risk, and how it was reported — a second dataset Working notes rather than a conclusion. Posting a small dataset on SELECT. It is mine, it is…
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4 | 1.3k | 1mo | |
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How this community labels and discusses unrefereed work — the long version
Asking directly, because I could not find a straight answer: How this community labels and discusses unrefereed work — the long version Reading an unrefereed manuscript properly, and asking whether I am doing…
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+18 | 23 | 21k | 2mo |
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About the Preprints category
Unrefereed work, clearly labelled as such, with the usual caveats stated once and taken seriously. This post is a community wiki: any member at trust level 3 or above can edit it, and every edit is recorded…
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+3 | 7 | 14k | 3mo |
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Publication bias detection and its low power — does this still hold?
The question in the title: Publication bias detection and its low power — does this still hold? I will give what I have already checked below so nobody repeats it. Collecting what is known about Publication…
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+24 | 28 | 2.4k | 3mo |
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The "under review" status pill and when a moderator applies it
Posting this under the heading it deserves: The "under review" status pill and when a moderator applies it Everything below is what sits behind that. A question about how this site should cite something that…
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+96 | 119 | 17k | 3mo |
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Coming back to: Measurement error in a self-reported exposure
Measurement error in a self-reported exposure — setting out what I have, and where I think it stops being reliable. Reading back through what has been written here about Measurement error, three questions…
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+23 | 27 | 49k | 3mo |
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Second pass at: What pooling buys you and what it destroys
Posting this under the heading it deserves: Second pass at: What pooling buys you and what it destroys Everything below is what sits behind that. Something about pooling buys does not reconcile and I would…
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+32 | 36 | 19k | 4mo |
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Prediction intervals and why they are more honest than confidence intervals
Posting this under the heading it deserves: Prediction intervals and why they are more honest than confidence intervals Everything below is what sits behind that. I have spent a fortnight trying to pin…
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+21 | 25 | 46k | 4mo |
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Preprint servers and what screening they do — the long version
On the subject in the title: Preprint servers and what screening they do — the long version Working notes rather than a conclusion. A preprint question rather than a question about the finding in it. The…
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+7 | 11 | 26k | 4mo |
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Citing a preprint in a maintained document: our rule and its reasoning
On the subject in the title: Citing a preprint in a maintained document: our rule and its reasoning Working notes rather than a conclusion. A preprint question rather than a question about the finding in it.…
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2 | 467 | 4mo | |
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Journal club: PIONEER 6 as a safety trial
Posting this under the heading it deserves: Journal club: PIONEER 6 as a safety trial Everything below is what sits behind that. Reading PIONEER 6 ( N Engl J Med , 2019) for the population rather than the…
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+14 | 18 | 262 | 5mo |
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