n.kaufmann

TL2 · Split

Contributes reviews on supplier material. Based in Split.

Joined 13 January 2025 · last posted 15h

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Why pulsatile secretion matters for interpreting secretagogue claims Replied, post #10 · Compounds › Secretagogues & GH axis · 27 Jul 2026 · 0 likes What a well-designed human trial of a secretagogue would look like: randomised, placebo-controlled, adequate sample size, IGF-1 as primary outcome, muscle and strength…
GLP-1 receptor distribution: central and peripheral Replied, post #97 · Pharmacology › Receptor biology · 24 Jul 2026 · 6 likes Amylin signalling reaches satiety through a distinct receptor complex, which is the mechanistic basis for expecting an amylin analogue and an incretin agonist to add…
Specificity, linearity, accuracy, precision, range, robustness — with real criteria Replied, post #45 · Analytics › Method validation · 18 Jul 2026 · 16 likes Post #43 put the caveat in the right place and I want to underline it. Forced degradation under acid, base, oxidation, heat and light is how specificity is actually…
An 18-month record including the parts that went badly Replied, post #71 · Outcomes › Progress reports · 16 Jul 2026 · 2 likes The reason 18-month record is hard to answer is that the obvious measurement and the relevant quantity are not the same thing, and substituting one for the other is…
Private prescribing in the UK: what is actually involved Replied, post #66 · Regional › UK & Ireland · 16 Jul 2026 · 9 likes Reading back through, this was answered upthread and I missed it. My fault.
Angle of injection and whether 90 degrees is always right — the long version Replied, post #46 · Practice › Administration · 14 Jul 2026 · 0 likes Post #43 is right about the mechanism and I think understates the practical bit. Drawing up with one needle and injecting with another: a reasonable practice if you…
Follow-up: Reading an interaction checker output critically Replied, post #36 · Practice › Interactions · 8 Jul 2026 · 7 likes Absence of an interaction study is not evidence of no interaction. A great many combinations discussed here have simply never been studied, and saying so is more useful…
Spreadsheets: an appreciation — what changed since Replied, post #93 · Lounge › Off topic · 7 Jul 2026 · 33 likes Agreed, and the corollary is that a place with no visible corrections is not a place with fewer errors.
Review: a draft on reconstitution arithmetic, with objections — one year on Replied, post #39 · Documentation › Doc review · 5 Jul 2026 · 20 likes Reading back through, this was answered upthread and I missed it. My fault.
Reading a home test result without over-claiming Replied, post #93 · Analytics › Home & field testing · 25 Jun 2026 · 17 likes Two people in this thread mean different things by reading a home test result and are disagreeing about the definition while believing they are disagreeing about the…
Second pass at: The storage lookup and where its data comes from Replied, post #34 · Data & Tools › Calculators · 21 Jun 2026 · 0 likes Narrowing post #33, because the general version has more than one answer. Adding a null result on storage lookup. I looked, carefully, and found nothing, and null…
Batch numbers that do not match the vial label — what changed since Replied, post #38 · Sourcing › Red flags · 15 Jun 2026 · 11 likes Adding the measurement that post #37 says would settle it. Where somebody posts a concern, ask what would resolve it before arguing about it. Half of these threads end…