s.diallo

TL2 · Faro

Contributes reviews on supplier material. Based in Faro.

Joined 19 October 2024 · last posted 9d

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Follow-up: Comparing two chromatograms from different laboratories, properly Replied, post #63 · Analytics › HPLC & UHPLC · 19 Jul 2026 · 1 like Mobile-phase preparation is a genuine source of between-laboratory variation. Acid concentration and organic modifier both shift retention, and neither is usually…
Follow-up: Reading an interaction checker output critically Replied, post #53 · Practice › Interactions · 18 Jul 2026 · 0 likes Alcohol is not contraindicated in the labelling and it does irritate a stomach that is already emptying slowly. There is no published interaction study, and the…
Coming back to: Preparing for an appointment: one page, three questions Replied, post #3 · Clinical › Prescriber conversations · 16 Jul 2026 · 33 likes The opening post describes the usual case. This is about the unusual one. A question phrased as "what would you want to see before considering X" is answerable and is…
Osteoarthritis and mechanical versus metabolic improvement — one year on Replied, post #45 · Clinical › Comorbidities · 12 Jul 2026 · 0 likes On Osteoarthritis and mechanical versus metabolic I would separate what is worth knowing from what is worth acting on. The first list is long and the second is short,…
Journal club: what we got wrong in an earlier session Replied, post #67 · Evidence › Journal club · 9 Jul 2026 · 0 likes Picking up post #64: that is the part I would want checked first. The most common failure mode is spending fifty minutes on the effect size and ten on the population.…
Sulfonylureas: the interaction most worth taking seriously — what changed since Replied, post #5 · Practice › Interactions · 8 Jul 2026 · 0 likes The arithmetic in post #2 is right; the assumption feeding it is the part to check. SGLT2 inhibitors: frequently co-administered and relevant to renal and…
Endotoxin and why it is a separate question from purity — what changed since Replied, post #68 · Analytics › Impurities & related substances · 6 Jul 2026 · 6 likes Oxidation at methionine and tryptophan: adds 16 per oxygen. Usually elutes earlier. Oxidation is common in storage, especially if the solution is exposed to light or if…
Journal club: orforglipron phase 2 and the non-peptide question Replied, post #106 · Evidence › Journal club · 30 Jun 2026 · 3 likes Thank you for taking the time. That was more work than a reply usually is.
An 18-month record including the parts that went badly Replied, post #49 · Outcomes › Progress reports · 23 Jun 2026 · 21 likes That is consistent with mine, for whatever one more account is worth.
Revisiting: The best-written scientific paper you have read Replied, post #47 · Lounge › Off topic · 23 Jun 2026 · 6 likes What would change my mind on best-written scientific paper is a second dataset collected by someone with no stake in the first. Until then I hold it loosely and I would…
Prescription requirements and telehealth models — a second dataset Replied, post #65 · Sourcing › Regulatory · 14 Jun 2026 · 1 like That is clearer than the version I had in my head. Thank you.
Semaglutide and gastric emptying — the mechanism behind most of the side-effect profile Replied, post #61 · Compounds › Semaglutide · 12 Jun 2026 · 11 likes Taking post #59 at face value and following it one step further. The C-cell question: semaglutide triggered medullary thyroid carcinoma in rodent toxicology studies. A…