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Devices · Pens & autoinjectors · continued

A pen that felt like it delivered nothing: diagnosing it afterwards posts 31–40

This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1 · go to the accepted answer.

BV
bias_varianceTL4Biostatistician5 Dec 2025#31

Post #30 put the caveat in the right place and I want to underline it.

Dose counters: pens show the remaining number of doses. When the counter reaches zero, the pen is empty and cannot deliver more. Noting the counter before injection prevents running out unexpectedly.

0 likes 8mo
IA
id.almeidaTL211 Dec 2025#32
trough_index, post #28: Post #27 put the caveat in the right place and I want to underline it. Storage after first use: most pens can be stored at room temperature after first use, even if unrefrigerated, for a limited time (often 28 days). Check your specific pen's labelling. Go to post

Priming: most pens require priming before the first use (injecting a small amount to fill the needle and line). Not priming can result in no dose being delivered on the first injection.

31 likes in reply to #28 8mo
BD
baseline_driftTL2Analytical chemist17 Dec 2025#33

Off-label dosing with a pen: if you want to deliver a dose different from the pen's pre-set steps (e.g., halfway between two step doses), that is off-label use. Some pens allow it; others do not. Confirm before attempting.

I would rather say I do not know than round it up to an answer.

15 likes 7mo
NK
n.krastevTL223 Dec 2025#34

The arithmetic in post #33 is right; the assumption feeding it is the part to check.

Reusability: some pens are single-use (throw away after one injection). Others can be reused until empty. Confirm which type you have. Reusing a single-use pen is ineffective because the mechanism does not reset.

The conclusion is tentative; the arithmetic underneath it is not.

6 likes 7mo
DO
d.oyelaranTL3Pharmacist29 Dec 2025#35
n.broberg, post #8: Pen confusion between compounds: if you are using multiple pens or alternating pens, confirming you have the correct pen before injection prevents administration errors. Check the label every time. I would treat the number as indicative rather than as a measurement. Go to post

A pen that will not dial to the intended dose is usually telling you the cartridge does not contain enough for it. That is a designed behaviour rather than a fault.

0 likes in reply to #8 7mo
CT
c.tullochTL24 Jan 2026#36
d.oyelaran, post #35: A pen that will not dial to the intended dose is usually telling you the cartridge does not contain enough for it. That is a designed behaviour rather than a fault. Go to post

Nothing here is medical advice, and pen technique is the single easiest thing to have demonstrated in person rather than learned from a description.

Caveat: everything above assumes the paperwork is what it says it is.

23 likes in reply to #35 7mo
K
KLindqvistTL4 Moderator10 Jan 2026#37

Saving this. It is the version I will quote when the question comes round again.

10 likes 7mo
FK
f.kimaniTL216 Jan 2026 · edited#38

Adding the measurement that post #36 says would settle it.

Pen confusion between compounds: if you are using multiple pens or alternating pens, confirming you have the correct pen before injection prevents administration errors. Check the label every time.

3 likes 6mo
LW
l.wikstromTL222 Jan 2026#39
h.mbeki, post #13: Needle installation: some pens require a fresh needle for each injection; others have a single needle that stays attached. Check the design of your pen. Go to post

A pen that has been dropped may not be visibly damaged and may not deliver accurately afterwards. Manufacturers say to replace rather than to test, and there is no test a user can do.

I would put a moderate confidence on that and no more.

3 likes in reply to #13 6mo
VN
v.nascimentoTL228 Jan 2026#40

Storage instructions for a pen typically differ before and after first use, and the in-use period is the one people miss. It is on the carton.

I checked the source rather than the summary, and they differ.

0 likes 6mo

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