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Regional · North America

Canadian access and provincial variation — one year on

EO
e.okaforTL216 Jul 2025#1

Canadian access and provincial variation — one year on Writing it up because I had to work it out twice and would rather nobody else did.

A follow-up question about Canadian access and provincial variation that I did not know to ask the first time.

The earlier thread answered what I asked. What I should have asked is below, and I think it is the one that matters.

52 likes 12mo
HF
h.friskTL217 Jul 2025 · edited#2

Two claims get bundled together under Canadian access and provincial variation and they need separating. The descriptive one — this is what was observed — is usually well supported. The causal one — this is why — usually is not.

Almost every disagreement in threads like this one dissolves once you say which of the two you are making.

14 likes 12mo
CR
crossover_reviewTL3Regular18 Jul 2025#3

The opening post and I disagree about the size of the effect, not about the direction.

The useful distinction on Canadian access and provincial variation is between what was measured and what was inferred from it. Both end up in the same sentence and only one of them has error bars.

2 likes 12mo
JS
j.sandvikTL218 Jul 2025#4

Appeals succeed more often than people expect when they answer the stated criterion point by point and include nothing else.

Scoping that to what I have actually seen rather than what I have read.

0 likes 12mo
RM
r.mcalisterTL3Regular18 Jul 2025#5

Quietly grateful for the plain phrasing. Not every thread gets that.

0 likes 12mo
CC
c.chowdhuryTL219 Jul 2025#6

The arithmetic in post #4 is right; the assumption feeding it is the part to check.

The denial letter is the specification for the appeal. It states a criterion and the job is to demonstrate that criterion in the letter's own language.

Posting it because the silence on this was starting to look like agreement.

20 likes 12mo
JR
j.rasmussenTL2Regular19 Jul 2025#7
c.chowdhury, post #6: The arithmetic in post #4 is right; the assumption feeding it is the part to check. The denial letter is the specification for the appeal. It states a criterion and the job is to demonstrate that criterion in the letter's own language. Posting it because the silence on this was starting to look like agreement. Go to post

On Canadian access and provincial variation, the part that usually goes wrong is that the question is asked as though it has one answer. It has a range, and the width of the range is the interesting bit.

If you can post the two or three numbers you are working from, several people here will check the arithmetic rather than argue about the conclusion.

5 likes in reply to #6 12mo
IB
i.balogunTL219 Jul 2025#8

Prior authorisation, step therapy, and exclusion of weight-management indications from coverage are common access barriers. The denial letter tells you which barrier you are facing.

0 likes 12mo
BV
bias_varianceTL4Biostatistician20 Jul 2025#9
c.chowdhury, post #6: The arithmetic in post #4 is right; the assumption feeding it is the part to check. The denial letter is the specification for the appeal. It states a criterion and the job is to demonstrate that criterion in the letter's own language. Posting it because the silence on this was starting to look like agreement. Go to post

Post #6 describes the usual case. This is about the unusual one.

Where a manufacturer runs a direct supply route, that is a commercial arrangement rather than a regulatory change, and it can end.

Anyone with a larger sample, please post it.

0 likes in reply to #6 12mo
SO
s.ostergaardTL220 Jul 2025#10
j.sandvik, post #4: Appeals succeed more often than people expect when they answer the stated criterion point by point and include nothing else. Scoping that to what I have actually seen rather than what I have read. Go to post

Adding the measurement that post #9 says would settle it.

Practical note on Canadian access and provincial variation: write down what you expect before you look. The number of times I have found what I went looking for is higher than chance would allow.

27 likes in reply to #4 12mo
KS
k.salinasTL220 Jul 2025#11

The arithmetic in post #10 is right; the assumption feeding it is the part to check.

I changed my mind about Canadian access and provincial variation after someone here asked me for the source and I could not produce one. That is worth saying out loud because it is the ordinary way it happens.

6 likes 12mo
DF
d.fontaineTL221 Jul 2025#12
k.salinas, post #11: The arithmetic in post #10 is right; the assumption feeding it is the part to check. I changed my mind about Canadian access and provincial variation after someone here asked me for the source and I could not produce one. That is worth saying out loud because it is the ordinary way it happens. Go to post

Private insurance gaps: some people have private insurance but medication is not covered. Manufacturer assistance programmes are the main resource for cost reduction.

Not the answer, but possibly the question that gets there.

15 likes in reply to #11 12mo
FS
f.sjobergTL221 Jul 2025#13
crossover_review, post #3: The opening post and I disagree about the size of the effect, not about the direction. The useful distinction on Canadian access and provincial variation is between what was measured and what was inferred from it. Both end up in the same sentence and only one of them has error bars. Go to post

Say which country and which state or province. Regulatory position, availability and practical route can all differ within the same continent and frequently do.

0 likes in reply to #3 12mo
DO
dr_okonkwoTL4 Moderator21 Jul 2025#14

Post #12 put the caveat in the right place and I want to underline it.

Formulary position changes on a schedule that is published in advance, which means a decision made now may be answering last year's formulary.

Not disagreeing with anyone above, just adding the bit I keep having to look up.

1 like 12mo
ML
m.lindqvistTL222 Jul 2025#15

Narrowing post #14, because the general version has more than one answer.

Canada: Health Canada licenses compounds. Prescribing is provincial. Compounds are prescription-only. Coverage varies between public and private insurance.

It is one reading of the data and not the only reasonable one.

9 likes 12mo
RR
r.restrepoTL222 Jul 2025#16
f.sjoberg, post #13: Say which country and which state or province. Regulatory position, availability and practical route can all differ within the same continent and frequently do. Go to post

Everything in post #12 holds. The case it does not cover is the one I have.

Canadian access and provincial variation has been discussed here with more heat than it deserves, mostly because two definitions have been in play the whole time.

22 likes in reply to #13 12mo
CC
c.correiaTL222 Jul 2025#17
ME
me.eriksenTL222 Jul 2025#18

Pharmacy practice varies between pharmacies within the same city, so two honest accounts can be entirely different.

2 likes 12mo
IA
i.almeidaTL223 Jul 2025 · edited#19
s.ostergaard, post #10: Adding the measurement that post #9 says would settle it. Practical note on Canadian access and provincial variation: write down what you expect before you look. The number of times I have found what I went looking for is higher than chance would allow. Go to post

Seconded. It reads as careful rather than confident, which is the right register.

1 like in reply to #10 12mo
DS
dr_seongTL3Physician23 Jul 2025#20
m.lindqvist, post #15: Narrowing post #14, because the general version has more than one answer. Canada: Health Canada licenses compounds. Prescribing is provincial. Compounds are prescription-only. Coverage varies between public and private insurance. It is one reading of the data and not the only reasonable one. Go to post

On post #16 — agreed on the reasoning, with one qualification.

Regional variation in North America: access differs substantially by US state and Canadian province. Postcode is a major determinant of access.

Reading it again, the caveat matters more than the finding.

0 likes in reply to #15 12mo
VM
v.milanoviTL3Regular23 Jul 2025#21

The honest answer on Canadian access and provincial variation is that it depends, and the useful part is the list of what it depends on. Four items, in rough order of how much they matter.

Most people get the first two right and then argue about the fourth.

4 likes 12mo
SL
s.lundgrenTL223 Jul 2025#22

This follows post #21 rather than contradicting it.

Indigenous healthcare systems: different indigenous healthcare systems have different medication access. Pathways through tribal health systems differ from mainstream healthcare.

0 likes 12mo
NB
n.bridgewaterTL224 Jul 2025#23
NL
ne.laurentTL224 Jul 2025#24

Following this. I have the same question and no better information than the first post.

18 likes 12mo
IT
integrator_traceTL2Member24 Jul 2025#25

Post #21 and I disagree about the size of the effect, not about the direction.

Counterpoint on Canadian access and provincial variation, offered without confidence: the same observation is consistent with a much duller explanation, and nobody has ruled the dull one out.

7 likes 12mo
NK
n.kirchnerTL224 Jul 2025#26

Taking post #25 at face value and following it one step further.

Anyone reporting an outcome should give the stated reason rather than the verdict. The reason is the part somebody else can use.

I have seen it go both ways, which is why I hedge.

1 like 12mo
AD
ambient_draftTL3Regular25 Jul 2025#27
r.restrepo, post #16: Everything in post #12 holds. The case it does not cover is the one I have. Canadian access and provincial variation has been discussed here with more heat than it deserves, mostly because two definitions have been in play the whole time. Go to post

Coverage decisions are made by individual payers and vary within the same jurisdiction. A denial from one says nothing about another.

The short answer was in the first line; everything after is the working.

0 likes in reply to #16 12mo
NC
n.chowdhuryTL225 Jul 2025#28

On Canadian access and provincial variation I would separate what is worth knowing from what is worth acting on. The first list is long and the second is short, and conflating them is how threads get heated.

24 likes 12mo
B
BDraganovTL2Member25 Jul 2025 · edited#29

If you are new and reading this thread for the answer to Canadian access and provincial variation: the answer is conditional, the conditions are in the third reply, and the rest of the thread is worth skipping.

11 likes 12mo
JP
j.palaciosTL225 Jul 2025#30
e.okafor, post #1: Canadian access and provincial variation — one year on Writing it up because I had to work it out twice and would rather nobody else did. A follow-up question about Canadian access and provincial variation that I did not know to ask the first time. The earlier thread answered what I asked. What I should have asked is below, and I think… Go to post

The public assessment documents published at approval are free, detailed and largely unread here.

That is all the detail I have. Someone else will have more.

3 likes in reply to #1 12mo