v.milanovi
TL3 Regular · Montpellier, FR
Long-standing member. Posts carefully and infrequently, mostly in the practice and analytics categories.
Joined 24 August 2024 · last posted 13h
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Composite endpoints and the component doing the work Replied, post #8 · Evidence › Trials · 27 Jul 2026 · 0 likes Adding a data point of agreement rather than a data point.
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Molecular mass of semaglutide and why the figure differs between sources Replied, post #111 · Compounds › Semaglutide · 27 Jul 2026 · 0 likes Coming back to post #107, because the follow-up matters more than the original answer. Reporting rather than recommending, on molecular mass of semaglutide. What…
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Revisiting: Why the absence of controlled human data on BPC-157 matters more than people… Replied, post #56 · Compounds › Repair & healing peptides · 26 Jul 2026 · 0 likes No disagreement from me. Posting only so the question does not look ignored.
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Follow-up: How compounding permissions changed when supply normalised Replied, post #77 · Sourcing › Regulatory · 26 Jul 2026 · 0 likes If you can confirm or contradict a position for your own region, please date the answer. An undated regional claim is the least useful thing in this category.
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Why a glucagon receptor agonist in a weight-loss compound is not a contradiction Replied, post #46 · Compounds › Retatrutide · 25 Jul 2026 · 3 likes Post #45 is the version of this I will quote in future. One addition. Phase 2 sample sizes are not adequate for safety characterisation of a novel triple agonist. Phase…
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Sleep quality changes during weight loss Replied, post #24 · Wellbeing › Sleep · 20 Jul 2026 · 3 likes Where I part company with post #22, and it is a narrow parting. Energy and sleep needs: rapid weight loss increases real metabolic stress. Sleep needs might increase…
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Follow-up: Sleep quality changes during weight loss Replied, post #74 · Wellbeing › Sleep · 19 Jul 2026 · 0 likes The arithmetic in post #73 is right; the assumption feeding it is the part to check. Where somebody uses positive airway pressure, changes in weight can change the…
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Named, unnamed and unspecified impurities as regulatory categories — the long version Replied, post #92 · Analytics › Impurities & related substances · 19 Jul 2026 · 1 like Coming back to post #90, because the follow-up matters more than the original answer. Racemisation produces a diastereomer that is mass-identical and…
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Selection into a registry and what it does to the estimate — a second dataset Replied, post #23 · Evidence › Study critique · 19 Jul 2026 · 0 likes Multiple comparisons without adjustment is a defensible choice when declared in advance and a problem when discovered afterwards. The registry entry settles which…
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I joined for one answer and stayed for a year — what changed my mind Replied, post #79 · Start Here › Welcome · 13 Jul 2026 · 27 likes The Lounge is a real category rather than a dumping ground. The sourcing rule still applies there, which surprises people, but the register is looser and nobody minds a…
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Coming back to: Where the four-week escalation interval comes from, and what it is not Replied, post #22 · Practice › Dosing & titration · 11 Jul 2026 · 1 like That reframing is the whole thing. The facts I already had.
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Athletes in weight-category sports: a different risk calculus Replied, post #19 · Clinical › Special populations · 9 Jul 2026 · 30 likes Post #16 is the version of this I will quote in future. One addition. Where I would push back on the athletes in weight-category sports consensus is the confidence, not…