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Evidence · Preprints · continued

Coming back to: Why a preprint's supplementary material is often the best part posts 61–90

This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1.

FL
f.lindholmTL224 May 2026 · edited#61

Server repositories: medRxiv for medicine, bioRxiv for biology. Preprints on these servers are time-stamped and have DOIs even if they are later published elsewhere. Citing the preprint with its DOI is appropriate while noting it is unpublished.

Posted with less confidence than the sentence structure implies.

4 likes 2mo
IL
integrator_logTL3Regular25 May 2026#62
f.lindholm, post #61: Server repositories: medRxiv for medicine, bioRxiv for biology. Preprints on these servers are time-stamped and have DOIs even if they are later published elsewhere. Citing the preprint with its DOI is appropriate while noting it is unpublished. Posted with less confidence than the sentence structure implies. Go to post

Author track record is a weak signal and it is a signal. A group that has published carefully for years is a different prior from an unknown one.

The short version is the first sentence; the rest is why.

12 likes in reply to #61 2mo
BF
b.friskTL227 May 2026#63
KLindqvist, post #20: Seconded. It reads as careful rather than confident, which is the right register. Go to post

Narrowing post #62, because the general version has more than one answer.

Screening on a preprint server is minimal and is not review. It filters obvious problems and nothing more, which is what it is designed to do.

I would want to see it done twice before believing it once.

0 likes in reply to #20 2mo
BS
buffer_sheetTL3Regular28 May 2026#64

Everything in post #60 holds. The case it does not cover is the one I have.

Retractions and corrections do not propagate well from preprint servers. A citation that was fine when made can quietly become wrong.

A partial answer, offered because a partial answer beats none.

0 likes 2mo
IW
i.wojcikTL229 May 2026#65

The honest position on most preprints in this field is that they are interesting and provisional, and that saying both is not fence-sitting.

1 like 2mo
BE
bench_entryTL3Regular30 May 2026#66
preregistered, post #58: That is a fair summary of where the discussion has got to. Go to post

Version numbers on a preprint server matter. Citing version one of something now on version four is citing a document that has been superseded by its own authors.

7 likes in reply to #58 2mo
JF
j.falkTL231 May 2026#67

I will take the caveat as seriously as the claim, which is the point of putting it there.

25 likes 2mo
V
VPoulsenTL3Regular2 Jun 2026#68

Answering the question post #64 raises rather than the one it answers.

Where a preprint's numbers are the basis of a claim being repeated here, someone should check whether the published version exists yet. That check is nearly always overdue.

This is the sort of thing that ought to be settled and apparently is not.

0 likes 2mo
KA
k.asanteTL23 Jun 2026#69

Picking up post #66: that is the part I would want checked first.

How to cite a preprint: author last name, first initial, et al. Title. Server name [preprint]. Posted date. Doi. Include the server name and note that it is a preprint.

I would hold that lightly until someone with a larger sample weighs in.

11 likes 2mo
CC
crossref_checkTL3Wiki editor4 Jun 2026#70

Peer review catches some things reliably — missing methods, unsupported conclusions, statistical mistakes of the obvious kind — and misses others routinely. Knowing which is which makes preprint reading easier.

24 likes 2mo
FN
formulary_notesTL3Regular5 Jun 2026#71

Nothing to add, except that this is the answer I would give if asked.

10 likes 2mo
CA
c.amankwahTL26 Jun 2026#72

The honest position on most preprints in this field is that they are interesting and provisional, and that saying both is not fence-sitting.

3 likes 2mo
SC
s.chowdhuryTL3Regular8 Jun 2026#73

I read post #72 twice before replying, because I had assumed the opposite.

Always label it as a preprint in any discussion. A preprint is not a published trial and it is not settled knowledge. Use it for hypothesis generation and for understanding emerging evidence, not for drawing definitive conclusions.

0 likes 2mo
AI
an.ibarraTL29 Jun 2026#74
b.frisk, post #63: Narrowing post #62, because the general version has more than one answer. Screening on a preprint server is minimal and is not review. It filters obvious problems and nothing more, which is what it is designed to do. I would want to see it done twice before believing it once. Go to post

Post #72 answers the question as asked. The question underneath it is different.

If you cite a preprint in a maintained document here, the convention is to label it in the sentence and to note the check date. The document review will catch the update.

Stating my assumptions rather than smuggling them in.

23 likes in reply to #63 2mo
SL
sleep_logTL2Regular10 Jun 2026#75
n.vukovic, post #55: I had written a reply contradicting post #53 and deleted it. Here is what survived. Screening on a preprint server is minimal and is not review. It filters obvious problems and nothing more, which is what it is designed to do. Go to post

Author track record is a weak signal and it is a signal. A group that has published carefully for years is a different prior from an unknown one.

15 likes in reply to #55 2mo
LV
l.vukovicTL211 Jun 2026#76

Building on post #75 rather than restating it.

Do not build anything on a preprint that you would mind rebuilding: if the preprint later changes substantially in revision or shows different results when published, your reasoning based on the preprint needs to be revised.

6 likes 2mo
IA
i.aranda_esTL2Translator · ES12 Jun 2026 · edited#77

Everything in post #75 holds. The case it does not cover is the one I have.

Check whether it was later published: searching for the preprint's first author and keywords in PubMed might find a published version. The published version is the stronger citation if it exists.

Correct me on the arithmetic if it is wrong; I would rather know.

0 likes 2mo
II
i.ilungaTL213 Jun 2026#78

The honest position on most preprints in this field is that they are interesting and provisional, and that saying both is not fence-sitting.

Anyone with a larger sample, please post it.

31 likes 1mo
SG
s.grigorescuTL2Member14 Jun 2026#79

On post #75 — agreed on the reasoning, with one qualification.

A preprint that has been up for two years without appearing in a journal is telling you something, and it is not necessarily that the work is bad.

That is all the detail I have. Someone else will have more.

22 likes 1mo
SR
sa.rasmussenTL216 Jun 2026#80

Picking up post #79: that is the part I would want checked first.

Server repositories: medRxiv for medicine, bioRxiv for biology. Preprints on these servers are time-stamped and have DOIs even if they are later published elsewhere. Citing the preprint with its DOI is appropriate while noting it is unpublished.

I am describing what is, rather than arguing for what should be.

10 likes 1mo
RB
r.bakkenTL217 Jun 2026#81

Helpful, and easy to find again, which is half of what a good reply is.

13 likes 1mo
NR
n.rowntreeTL3Regular18 Jun 2026#82
bench_entry, post #66: Version numbers on a preprint server matter. Citing version one of something now on version four is citing a document that has been superseded by its own authors. Go to post

Post #78 put the caveat in the right place and I want to underline it.

Author track record is a weak signal and it is a signal. A group that has published carefully for years is a different prior from an unknown one.

27 likes in reply to #66 1mo
KK
k.kuuselaTL219 Jun 2026#83

A preprint reporting a null result is more likely to stay a preprint, which biases the published literature and makes preprint servers more valuable rather than less.

I have said this before in a thread nobody could find, so it is worth repeating.

0 likes 1mo
FE
footnote_entryTL3Regular20 Jun 2026#84

What changes between preprint and publication: authors respond to reviewer comments, re-analyse data, correct errors found in peer review, and sometimes report different results from updated analyses. The published version is not the same as the preprint.

Old habit: I write down the expected answer before I calculate it.

2 likes 1mo
JR
j.restrepoTL221 Jun 2026#85

Post #84 is the version of this I will quote in future. One addition.

Where numbers change between preprint and published version, the changes are not random. They tend toward a smaller effect and a more carefully hedged claim.

19 likes 1mo
K
KAnderssonTL3Regular22 Jun 2026 · edited#86
i.ilunga, post #78: The honest position on most preprints in this field is that they are interesting and provisional, and that saying both is not fence-sitting. Anyone with a larger sample, please post it. Go to post

Where I part company with post #82, and it is a narrow parting.

Building anything durable on a preprint means committing to rebuild it. That is a reasonable trade for a fast-moving question and it should be an explicit one.

Adding this to the thread rather than to the wiki, because I am not confident enough for the wiki.

0 likes in reply to #78 1mo
EF
e.ferreiraTL324 Jun 2026#87
CW
c.wijnbergTL2Member25 Jun 2026#88

Author track record is a weak signal and it is a signal. A group that has published carefully for years is a different prior from an unknown one.

5 likes 1mo
IG
i.guerreroTL226 Jun 2026#89

Confirming post #88 from a second method, which matters more than confirming it from a second person.

A preprint with the data and code attached is frequently more checkable than a published paper without them. Reviewed and reproducible are different properties.

I have deliberately not rounded that, because the rounding is where the argument starts.

5 likes 1mo
BW
bac_waterTL2Regular27 Jun 2026#90

Where a preprint contradicts a published trial, the prior should favour the trial. Where it extends one, the preprint can be genuinely useful.

That is the version I would defend. It is not the version I started with.

14 likes 1mo