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Practice · Administration

Follow-up: A partial dose because the pen emptied mid-injection

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outline_firstTL3Wiki editor8 Jun 2024#1

Posting this under the heading it deserves: A partial dose because the pen emptied mid-injection Everything below is what sits behind that.

A follow-up question about partial dose because the pen that I did not know to ask the first time.

The earlier thread answered what I asked. What I should have asked is below, and I think it is the one that matters.

0 likes 2.1y
R
RodriguesTL3Regular18 Jun 2024#2

I read the opening post twice before replying, because I had assumed the opposite.

A genuinely late dose: the labelling generally says that if the next dose is more than a couple of days away, take it as soon as you notice. If the next dose is close, skip it and resume the schedule. The reasoning follows from the long half-life; you are perturbing a slowly moving average.

3 likes 2.1y
RS
r.sobczakTL225 Jun 2024#3
outline_first, post #1: Posting this under the heading it deserves: A partial dose because the pen emptied mid-injection Everything below is what sits behind that. A follow-up question about partial dose because the pen that I did not know to ask the first time. The earlier thread answered what I asked. What I should have asked is below, and I think it is the… Go to post

This follows the opening post rather than contradicting it.

If you have to inject at a different time of day than usual, that is a much smaller perturbation than it feels for a weekly compound with a week-long half-life.

16 likes in reply to #1 2.1y
EA
e.almeidaTL2Member1 Jul 2024#4

Partial dose because the pen would be much easier to settle if anyone reported the denominator. Almost nobody reports the denominator.

31 likes 2.1y
NR
n.ramosTL27 Jul 2024#5
I
IHollingworthTL2Member13 Jul 2024#6
outline_first, post #1: Posting this under the heading it deserves: A partial dose because the pen emptied mid-injection Everything below is what sits behind that. A follow-up question about partial dose because the pen that I did not know to ask the first time. The earlier thread answered what I asked. What I should have asked is below, and I think it is the… Go to post

Research-use-only preparations are not supplied with administration instructions because they are not supplied for administration. Anything in this subcategory describing technique is describing what members do, not what a manufacturer recommends.

I would be glad to be shown a cleaner way of putting this.

1 like in reply to #1 2y
MM
m.marchettiTL218 Jul 2024#7

Taking post #4 at face value and following it one step further.

Where the partial dose because the pen reasoning breaks down for me is the step from the group result to the individual case. That step is almost never argued for.

10 likes 2y
LS
l.sarkissianTL2Member23 Jul 2024#8

No notes. Posting so the count is not one.

23 likes 2y
CN
c.nybergTL228 Jul 2024#9

Adding a data point of agreement rather than a data point.

3 likes 2y
HH
h.hutchingsTL1Member2 Aug 2024#10
e.almeida, post #4: Partial dose because the pen would be much easier to settle if anyone reported the denominator. Almost nobody reports the denominator. Go to post

Trying to state the partial dose because the pen position in a way that someone who disagrees would recognise as fair, because I do not think the version in this thread passes that test.

10 likes in reply to #4 2y
SB
s.bergstromTL27 Aug 2024#11
h.hutchings, post #10: Trying to state the partial dose because the pen position in a way that someone who disagrees would recognise as fair, because I do not think the version in this thread passes that test. Go to post

Bleeding at the injection site: normal and usually minimal. A little blood at the needle site after withdrawal is not a reason to assume you lost a significant dose. The needle passed through tissue and there is a small amount of bleeding in the tract.

24 likes in reply to #10 2y
K
KTurkingtonTL3Regular11 Aug 2024#12

Confirming post #10 from a second method, which matters more than confirming it from a second person.

The single most common technique error described here is drawing to the wrong graduation because the barrel was read at an angle. Read it straight on, at eye level, every time.

That is the version I use. It may not be the version that is correct.

11 likes 2y
FN
f.novakTL216 Aug 2024#13
TI
trough_indexTL3Regular20 Aug 2024#14

The question underneath partial dose because the pen is usually "how would I tell?" rather than "what is true?", and that one has a method attached to it.

Write down what you would expect to see under each hypothesis before you collect anything. If they predict the same observation, collecting it will not help.

0 likes 23mo
NM
n.moreauTL225 Aug 2024#15
f.novak, post #13: I would put moderate confidence on the mainstream reading of partial dose because the pen and no more. That is not scepticism for its own sake; it is where the sourcing actually stops. Go to post

If you have to inject at a different time of day than usual, that is a much smaller perturbation than it feels for a weekly compound with a week-long half-life.

17 likes in reply to #13 23mo

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