n.ramos
TL2 · Bologna
Contributes reviews on supplier material. Based in Bologna.
Joined 30 December 2024 · last posted 6d
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Reading a rodent study on a secretagogue without over-extrapolating — the long version Replied, post #55 · Compounds › Secretagogues & GH axis · 22 Jul 2026 · 5 likes Effects reported at the level of appetite are the most consistently described and the most mechanistically direct for the ghrelin-receptor compounds, which is not what…
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Journal club: what we got wrong in an earlier session Replied, post #90 · Evidence › Journal club · 16 Jul 2026 · 21 likes Post #88 and I disagree about the size of the effect, not about the direction. A conflict-of-interest statement is worth reading aloud and is worth very little as a…
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Revisiting: The report format the maintainers ask for, and why each field is there Replied, post #100 · Sourcing › Vendor reports · 12 Jul 2026 · 2 likes Fair, and the limits you put on it are the part I will remember.
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An 18-month record including the parts that went badly Replied, post #66 · Outcomes › Progress reports · 11 Jul 2026 · 26 likes Two people in this thread mean different things by 18-month record and are disagreeing about the definition while believing they are disagreeing about the facts. Worth…
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About the Impurities & related substances category Replied, post #9 · Analytics › Impurities & related substances · 4 Jul 2026 · 7 likes Building on post #6 rather than restating it. Peptide impurities that differ by a single residue are the hardest to resolve and the most likely to be biologically…
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Why cagrilintide alone is discussed so much less than in combination — does this still… Replied, post #18 · Compounds › Cagrilintide & amylin analogues · 3 Jul 2026 · 6 likes The arithmetic in post #17 is right; the assumption feeding it is the part to check. Cagrilintide alone is well covered in the tag pages, and the older discussions are…
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Revisiting: How this community labels and discusses unrefereed work Replied, post #6 · Evidence › Preprints · 22 Jun 2026 · 23 likes Post #5 is the version of this I will quote in future. One addition. The honest position on most preprints in this field is that they are interesting and provisional,…
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Naming conventions for research peptides and the confusion they cause Replied, post #16 · Compounds › Other compounds · 16 Jun 2026 · 7 likes Confirming post #13 from a second method, which matters more than confirming it from a second person. This subcategory exists because some people will research…
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Second pass at: Metformin co-administration and additive GI effects Replied, post #124 · Practice › Interactions · 12 Jun 2026 · 12 likes Agreed on Metformin co-administration, with one qualification that I think matters. The reasoning holds for the case as described. Change the starting assumption and it…
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Coming back to: Specificity, linearity, accuracy, precision, range, robustness — with… Replied, post #47 · Analytics › Method validation · 8 Jun 2026 · 21 likes Robustness testing deliberately varies the parameters most likely to drift — organic percentage, pH, temperature, flow — and shows the result does not. It is the part…
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A certificate whose chromatogram axes do not match its stated method — one year on Replied, post #41 · Sourcing › Red flags · 4 Jun 2026 · 7 likes I have no financial interest in anything named in this thread and I want to say so before I comment on certificate whose chromatogram axes, because it is the sort of…
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Semaglutide and gastric emptying — the mechanism behind most of the side-effect profile Replied, post #44 · Compounds › Semaglutide · 30 May 2026 · 0 likes Gallbladder events appear in the labelling for this class and are more common with larger, faster weight reduction. The mechanism is not specific to the drug — rapid…