Compounds · Secretagogues & GH axis

Ipamorelin selectivity claims and where they came from — a second dataset

Compounds › Secretagogues & GH axis CJC-1295 GHRP class tesamorelin ipamorelin needs a source observational data

t.ibarraTL26 Apr 2025#1

Posting this under the heading it deserves: Ipamorelin selectivity claims and where they came from — a second dataset Everything below is what sits behind that.

Posting a small dataset on Ipamorelin selectivity claims. It is mine, it is uncontrolled, and the method is stated so it can be discounted appropriately.

What I would like is not agreement but a second dataset collected by someone with no stake in mine. If one exists I would rather read it than argue for this one.

24 likes 16mo

DOdendaalTL3Regular30 Apr 2025 · edited#2

Ipamorelin is usually described as selective in that it produces less of an effect on cortisol and prolactin than earlier compounds in the family. Selective is a relative claim and the comparison group matters.

Adding the caveat now so it does not have to be extracted later.

27 likes 15mo

c.marchettiTL216 May 2025#3

Development history is more informative than speculation: ipamorelin was investigated clinically for post-operative ileus and was not taken forward to registration. That it was not brought to market tells you something about the cost-benefit calculation that any amount of forum enthusiasm does not.

0 likes 14mo

This topic was referenced in

Evidence quality in the secretagogue literature: an honest assessmentCompounds › Secretagogues & GH axis · 2 replies

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