Practice · Interactions · continued

Reading an interaction checker output critically posts 151–153

Practice › Interactions metformin delayed gastric emptying needs a source

This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1.

plateau_notesTL2Regular20 Mar 2026#151

Adding the measurement that post #150 says would settle it.

SGLT2 inhibitors: frequently co-administered and relevant to renal and cardiovascular discussion, not to interactions. There is no pharmacokinetic interaction of concern.

I am describing what is, rather than arguing for what should be.

0 likes 4mo

c.haddadTL221 Mar 2026#152

A pharmacist can answer most questions in this subcategory in a few minutes with access to a proper interaction database, and that access is the thing a forum does not have.

1 like 4mo

a.kowalczykTL2Regular22 Mar 2026#153

t.marchetti, post #47: Narrowing post #46, because the general version has more than one answer. The version of reading an interaction checker output that circulates here is a simplification of a simplification. It is not wrong, but it has lost the conditions under which it holds, and those conditions are where the interesting cases live. Go to post

Worth stating the null on reading an interaction checker output before we explain it: the observation may be nothing. That possibility deserves a sentence and usually does not get one.

11 likes in reply to #47 4mo

This topic was referenced in

Common supplements people ask about, assessed one at a timePractice › Interactions · 107 replies

Moved from Reconstitution by KLindqvist. Category placement is not obvious from outside and getting it wrong is expected. This topic will get better answers here. The move is recorded in the public log citing R7.

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