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Data & Tools · Calculators · continued

Validating a calculator against hand arithmetic — what changed since posts 121–138

This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1 · go to the accepted answer.

FA
f.abrahamsenTL2Member8 Jun 2025#121
t.abubakar, post #59: Do the arithmetic by hand the first few times, whatever tool you use afterwards. A calculator with a wrong input gives a confident wrong answer and there is nothing in the interface to tell you. Take the reasoning and check the arithmetic; I do not always get it right. Go to post

Nothing a calculator produces is medical advice, and a correct calculation on inappropriate inputs is still an inappropriate answer.

This has been discussed before and I could not find the thread, so, again.

0 likes in reply to #59 14mo
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e.coelhoTL29 Jun 2025#122

Marking my place. If it changes for me I will come back and say so.

0 likes 14mo
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g.haalandTL3Regular9 Jun 2025#123

Where a calculator and your own arithmetic disagree, the productive move is to find which step differs rather than to decide which is right.

14 likes 14mo
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il.dumitruTL29 Jun 2025#124
m.dalgaard, post #88: That is a fair summary of where the discussion has got to. Go to post

Narrowing post #123, because the general version has more than one answer.

Checking a tool against a worked example you already trust is five minutes well spent, and it is the only validation available to a user.

It is a small point and it changes the answer, which is an awkward combination.

5 likes in reply to #88 14mo
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g.ibarraTL210 Jun 2025#125
z.szabo, post #74: Nothing a calculator produces is medical advice, and a correct calculation on inappropriate inputs is still an inappropriate answer. Go to post

Post #123 put the caveat in the right place and I want to underline it.

A saved calculation is worth more than a remembered one. Write down the inputs alongside the result, because the result alone is unverifiable a month later.

Not disagreeing with anyone above, just adding the bit I keep having to look up.

2 likes in reply to #74 14mo
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m.yilmazTL210 Jun 2025#126

I keep a log for Validating a calculator against hand specifically because my memory of it turned out to be systematically wrong in one direction. Six weeks of notes cost nothing and settled it.

0 likes 14mo
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a.salcedoTL3Regular11 Jun 2025 · edited#127

Dose equivalence calculator: compounds have different potencies. The calculator is provided with a caveat: "equivalence" is not precise and individual response varies. It is a rough starting point, not a dose prescription.

20 likes 14mo
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ka.haddadTL211 Jun 2025#128

Adding the boring version of Validating a calculator against hand, because the interesting version keeps getting posted and the boring one is usually right.

Check the ordinary explanations, in order, and stop when one of them accounts for what you are seeing. Most of the time the second one does.

8 likes 14mo
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MJayawardenaTL3Regular12 Jun 2025#129

No notes. Posting so the count is not one.

4 likes 14mo
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n.zielinskiTL212 Jun 2025#130

Picking up post #127: that is the part I would want checked first.

Titration planning: a calculator that shows you the escalation schedule for different starting and ending doses can help you visualize your path. Actual path might be slower or adjusted for tolerability.

I have kept the units in throughout, for the obvious reason.

0 likes 14mo
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erratum_fileTL3Regular13 Jun 2025#131
n.ibarra, post #80: Storage lookup: which conditions (temperature, time) are you considering storing in, and how much stability loss is expected? The calculator gives a rough estimate based on typical stability data. Not a substitute for your compound's specific stability data. Marking that as an opinion rather than a finding. Go to post

Validating a calculator against hand is one of those subjects where the general answer and the answer for a specific case diverge, and the thread will go in circles until someone says which one is being asked for.

2 likes in reply to #80 13mo
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i.grimaldiTL213 Jun 2025#132

For anyone finding this later: the short answer on Validating a calculator against hand is that it depends on one thing, and the rest of the thread is people identifying which thing.

9 likes 13mo
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RidgewayTL3Regular13 Jun 2025#133

Confirming post #130 from a second method, which matters more than confirming it from a second person.

A calculator that shows its working is worth ten that give an answer. The whole value is being able to see which step you disagree with.

It reads as pedantry until the day it does not.

29 likes 13mo
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i.dumitruTL214 Jun 2025#134

Clear enough that I do not think I have a follow-up, which is unusual.

0 likes 13mo
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endpoint_lineTL3Regular14 Jun 2025#135
r.zielinski, post #68: A saved calculation is worth more than a remembered one. Write down the inputs alongside the result, because the result alone is unverifiable a month later. Go to post

Tools that run entirely in the browser send nothing anywhere, which matters more to some people here than others and is worth stating either way.

Second-hand, so weight it accordingly.

1 like in reply to #68 13mo
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in.guerreroTL215 Jun 2025#136
i.dumitru, post #99: Reporting rather than recommending, on Validating a calculator against hand. What happened is above. Whether it should have is a different question and not one I am qualified to answer. Go to post

Post #132 describes the usual case. This is about the unusual one.

The useful distinction on Validating a calculator against hand is between what was measured and what was inferred from it. Both end up in the same sentence and only one of them has error bars.

5 likes in reply to #99 13mo
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h.nicolaidesTL3Regular15 Jun 2025#137

Post #135 is the version of this I will quote in future. One addition.

The calculators maintained on this site are open-source and verifiable. They are intended to check arithmetic, not to replace medical judgement. Using them is optional and they are provided for convenience.

21 likes 13mo
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ca.vermeulenTL216 Jun 2025#138

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