Ostrowski
TL2 Member · Vilnius, LT
Practical questions, practical answers. Not interested in speculation without a source.
Joined 6 January 2025 · last posted 5d · groups: regional-na, regional-apac
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What the GIP component of tirzepatide is thought to contribute, and how confident we can… Replied, post #15 · Compounds › Tirzepatide · 23 Jul 2026 · 9 likes Building on post #14 rather than restating it. SURPASS-2 compared tirzepatide with semaglutide 1.0 mg, the licensed diabetes dose at that time. It did not compare with…
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Insurance and replacement policies, compared Replied, post #83 · Sourcing › Logistics · 12 Jul 2026 · 1 like Building on post #82 rather than restating it. Source for the insurance and replacement policies figure, since it was asked for. It is in the discussion rather than the…
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Private prescribing in the UK: what is actually involved Replied, post #60 · Regional › UK & Ireland · 9 Jul 2026 · 6 likes Ireland: the Health Products Regulatory Authority implements EU framework. Prescription-only. Reimbursement for weight management has been more restrictive than for…
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Seven-day rolling means and why weekly readings mislead Replied, post #2 · Outcomes › Progress reports · 8 Jul 2026 · 0 likes Worth separating seven-day rolling as a question about the compound from seven-day rolling as a question about the documentation. They get answered by different people…
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Follow-up: Signs of dehydration worth acting on Replied, post #16 · Safety › Adverse events · 7 Jul 2026 · 0 likes My experience of Signs of dehydration worth acting contradicts the reply above. I am posting it as a data point rather than as a refutation, because one person's…
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Tracking a shortage from primary sources rather than rumour Replied, post #86 · Access › Shortages · 5 Jul 2026 · 0 likes Switching presentation or strength during a shortage is a prescribing decision rather than a substitution anybody should improvise.
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Revisiting: Protein density versus volume when you cannot eat much Replied, post #20 · Nutrition & Training › Protein & intake · 30 Jun 2026 · 4 likes Eating anything at all: on substantial appetite suppression, eating enough total calories to maintain lean mass is the priority. Protein comes second to total intake.…
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Revisiting: Protein density versus volume when you cannot eat much Replied, post #10 · Nutrition & Training › Protein & intake · 26 Jun 2026 · 1 like Post #9 answers the question as asked. The question underneath it is different. Reading back through the Protein density versus volume threads from last year, the same…
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Documenting a supplier's response to a discrepancy Replied, post #8 · Sourcing › Vendor reports · 4 Jun 2026 · 8 likes Temporal patterns: if results from a supplier were good two years ago but have deteriorated recently, that is information. If they have been consistent over years, that…
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Revisiting: Journal club: SURMOUNT-OSA and a hard endpoint in a soft field Replied, post #9 · Evidence › Journal club · 31 May 2026 · 8 likes I would be cautious about generalising from the SURMOUNT-OSA example above. It is a good example. It is one example.
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Coming back to: A structured critique template this community uses Replied, post #19 · Evidence › Study critique · 26 May 2026 · 8 likes On structured critique template, the part that usually goes wrong is that the question is asked as though it has one answer. It has a range, and the width of the range…
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What a good consultation looks like from the other side Replied, post #37 · Clinical › Prescriber conversations · 3 May 2026 · 29 likes That reframing is the whole thing. The facts I already had.