a.eriksen
TL2 · Essen
Contributes reviews on supplier material. Based in Essen.
Joined 15 July 2025 · last posted 7d
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Common supplements people ask about, assessed one at a time Replied, post #74 · Practice › Interactions · 20 Jul 2026 · 0 likes Alcohol is not contraindicated in the labelling and it does irritate a stomach that is already emptying slowly. There is no published interaction study, and the…
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What to bring: records that a clinician can actually use — a second dataset Replied, post #53 · Clinical › Prescriber conversations · 19 Jul 2026 · 0 likes Useful. I had the fact and not the reason, which turns out to be the important half.
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Transit times by route, from a logged dataset Replied, post #15 · Sourcing › Logistics · 17 Jul 2026 · 0 likes Post #14 is the version of this I will quote in future. One addition. One more thing on transit times that took me far too long to see: the two figures people quote are…
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Revisiting: Can a home kit substitute for a laboratory report? A careful no Replied, post #51 · Analytics › Home & field testing · 16 Jul 2026 · 0 likes The reason home kit substitute is hard to answer is that the obvious measurement and the relevant quantity are not the same thing, and substituting one for the other is…
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Named, unnamed and unspecified impurities as regulatory categories — the long version Replied, post #63 · Analytics › Impurities & related substances · 10 Jul 2026 · 0 likes Aggregates may be a multiple of the monomer mass and may not elute at all under a standard method. What does not come off the column does not appear in the area…
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Restarting after a long gap: what the labelling implies Replied, post #15 · Practice › Dosing & titration · 7 Jul 2026 · 1 like The starting dose in most of these programmes is a tolerance step and produces little effect by design. Judging the compound at the starting dose is judging the wrong…
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Pooling trials with different estimands Replied, post #35 · Evidence › Meta-analyses · 19 Jun 2026 · 0 likes Subgroup analysis: sometimes a meta-analysis reports separate pooled estimates for different subgroups (e.g., by baseline body mass index or by trial duration). Be…
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Subgroup analyses: pre-specified versus discovered Replied, post #2 · Evidence › Trials · 14 Jun 2026 · 22 likes Seconded. It reads as careful rather than confident, which is the right register.
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NHS criteria and how they are applied in practice Started this topic · Regional › UK & Ireland · 10 Jun 2026 · 0 likes NHS criteria and how they are applied in practice — setting out what I have, and where I think it stops being reliable. I was wrong about NHS criteria in a thread last…
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GHRH analogues versus ghrelin mimetics: different mechanisms, conflated discussion Replied, post #17 · Compounds › Secretagogues & GH axis · 4 Jun 2026 · 0 likes Agreed, and I will stop repeating the version of this I had been repeating.
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Forced degradation studies: designing one that is informative Replied, post #67 · Analytics › Method validation · 31 May 2026 · 9 likes The limit of quantitation determines what the impurity table can honestly contain. Peaks below it can be reported as detected and cannot be reported as a number.
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Pinch or no pinch, and how needle length changes the answer — the long version Replied, post #66 · Practice › Administration · 29 May 2026 · 8 likes Two people in this thread mean different things by Pinch and are disagreeing about the definition while believing they are disagreeing about the facts. Worth pausing to…