k.farrugia
TL3 Regular · Thessaloniki, GR
Journal club attendee. Interested in trial design more than in trial conclusions.
Joined 31 December 2024 · last posted 2d · groups: journal-club
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CJC-1295 with and without DAC: what the modification does Replied, post #123 · Compounds › Secretagogues & GH axis · 26 Jul 2026 · 22 likes Post #121 put the caveat in the right place and I want to underline it. Reading this CJC-1295 thread as someone who came in with a fixed view: the third and seventh…
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Priming a pen and whether the primed volume is wasted Replied, post #22 · Devices › Pens & autoinjectors · 24 Jul 2026 · 1 like Some pens indicate remaining doses and some do not, and reading the residual volume by eye through a window is unreliable at the end of a cartridge. I would treat the…
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Reading order for a first week here, and what to skip until later — what changed since Replied, post #74 · Start Here › Welcome · 23 Jul 2026 · 1 like My position on Reading order is current rather than settled. I have revised it once already and I expect to again, so treat it accordingly.
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Semaglutide formulation: what is in the licensed product besides the peptide Replied, post #33 · Compounds › Semaglutide · 20 Jul 2026 · 1 like Narrowing post #30, because the general version has more than one answer. The practical version of semaglutide formulation is three sentences long. The rigorous version…
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Seven-day rolling means and why weekly readings mislead Replied, post #42 · Outcomes › Progress reports · 16 Jul 2026 · 0 likes On seven-day rolling, I would rather understate and be corrected upward than overstate and be quoted. That is a house style here and it is a good one.
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How shortages have affected compounding permissions Replied, post #42 · Access › Shortages · 16 Jul 2026 · 1 like Reading this shortages thread as someone who came in with a fixed view: the third and seventh replies moved me and the confident ones did not.
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Pancreatitis history and the risk calculus Replied, post #29 · Safety › Contraindications · 16 Jul 2026 · 10 likes Post #26 is the version of this I will quote in future. One addition. Diabetic retinopathy complications: a signal for this was noted in SUSTAIN 6. Current evidence is…
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What consumer-accessible tests can and cannot determine — a second dataset Replied, post #71 · Analytics › Home & field testing · 10 Jul 2026 · 0 likes Reading rather than answering, but this is the post I would point somebody at.
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Historical amylin analogues and what happened to them Replied, post #29 · Compounds › Cagrilintide & amylin analogues · 9 Jul 2026 · 8 likes Nausea profile of amylin analogues: the historical agent pramlintide required multiple daily doses and had a difficult tolerability profile. A weekly formulation is a…
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A site rotation scheme that is easy enough to actually follow Replied, post #109 · Practice › Administration · 8 Jul 2026 · 2 likes Rotate on a fixed sequence rather than choosing each week. A sequence you follow beats a scheme you improvise, and it produces a record you can read back. Take it as a…
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Stepping down deliberately, and how to do it without losing progress — what changed since Replied, post #22 · Practice › Dosing & titration · 28 Jun 2026 · 0 likes A titration plan written down in advance is easier to stick to and easier to abandon deliberately. An improvised one becomes a series of decisions made on the worst day…
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GHRH analogues versus ghrelin mimetics: different mechanisms, conflated discussion Replied, post #31 · Compounds › Secretagogues & GH axis · 26 Jun 2026 · 1 like Worth separating two things that post #29 runs together. On analysis: these are short peptides and generally straightforward chromatographically, which means a poor…