The Peptide CommonsEst. May 2024
Independent. We sell nothing and are affiliated with no manufacturer or pharmacy. Every moderation action is logged in public
Practice · Interactions · continued

[2026 update] Antibiotics and a course of something with delayed emptying posts 91–98

This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1.

LI
l.ibarraTL2Regular26 Jul 2026#91

Reading back through, this was answered upthread and I missed it. My fault.

2 likes 2d
AK
a.kirchnerTL226 Jul 2026 · edited#92
s.karlsen_rph, post #22: Reporting rather than recommending, on Antibiotics. What happened is above. Whether it should have is a different question and not one I am qualified to answer. Go to post

What I want from this Antibiotics thread is the list of things that would need to be true for the claim to hold. If we can write that list, we can check it.

0 likes in reply to #22 2d
RF
resistance_firstTL2Regular26 Jul 2026#93
e.lehtinen, post #84: Practical note on Antibiotics: write down what you expect before you look. The number of times I have found what I went looking for is higher than chance would allow. Go to post

A pharmacist can answer most questions in this subcategory in a few minutes with access to a proper interaction database, and that access is the thing a forum does not have.

21 likes in reply to #84 2d
AD
a.delgadoTL226 Jul 2026#94

The thing about Antibiotics that took me longest to accept is that a plausible mechanism is not evidence of an effect. It is a reason to look, not a result.

9 likes 1d
P
preregisteredTL3Research methods27 Jul 2026#95

I read post #92 twice before replying, because I had assumed the opposite.

Antibiotics: I have looked for the primary source twice and failed twice. Either it does not exist or it is somewhere I do not know to look, and I would like to know which.

5 likes 1d
JV
j.vogelTL227 Jul 2026#96
j.vandermolen, post #13: I read post #11 twice before replying, because I had assumed the opposite. The number people quote for Antibiotics is a central estimate presented without its interval, and the interval is wide enough that the estimate is nearly uninformative on its own. Go to post

Post #95 answers the question as asked. The question underneath it is different.

Where a published interaction study exists it usually reports an area-under-curve ratio, and that number is far more informative than a yes-or-no answer.

I have deliberately not rounded that, because the rounding is where the argument starts.

0 likes in reply to #13 1d
AD
appeals_deskTL3Regular27 Jul 2026#97
k.marchand, post #77: Practical answer on Antibiotics, since the theoretical one is upthread: do the simplest check first, write down the result, and only then decide whether the complicated explanation is needed. It usually is not. Go to post

Delayed gastric emptying is the mechanism behind most of the plausible interactions in this class: anything whose absorption depends on how quickly the stomach empties can behave differently.

I would treat the number as indicative rather than as a measurement.

28 likes in reply to #77 18h
YR
y.rahimiTL227 Jul 2026#98

Anticoagulant questions come up regularly and are the clearest case for professional advice rather than discussion, because the consequence of being wrong is not gradual.

I have separated what I observed from what I concluded, which does not always happen.

14 likes 13h
Moved from Side effects by s.leclerc. Category placement is not obvious from outside and getting it wrong is expected. This topic will get better answers here. The move is recorded in the public log citing R7.

Suggested topics

TopicParticipantsRepliesViewsActivity
Sulfonylureas: the interaction most worth taking seriously — what changed since
On the subject in the title: Sulfonylureas: the interaction most worth taking seriously — what changed since Working notes rather than a conclusion. What changes if the standard account of Sulfonylureas is…
TWMDNSNGSD+3 7 35k 1d
Common supplements people ask about, assessed one at a time
Common supplements people ask about, assessed one at a time — setting out what I have, and where I think it stops being reliable. A follow-up question about common supplements that I did not know to ask the…
NIASLCSFCM+101 107 28k 12h
Grapefruit: why this class is not the class that cares
Grapefruit: why this class is not the class that cares Writing it up because I had to work it out twice and would rather nobody else did. I was wrong about grapefruit in a thread last spring and I would like…
PEOCLTEOND+126 139 4k 4mo
Oral contraceptives and delayed emptying: what the data shows
Posting this under the heading it deserves: Oral contraceptives and delayed emptying: what the data shows Everything below is what sits behind that. The question about oral contraceptives and delayed emptying…
CAWMDEMSBV+63 71 5.9k 2y
Follow-up: Reading an interaction checker output critically
Reading an interaction checker output critically — setting out what I have, and where I think it stops being reliable. A follow-up question about Reading an interaction checker output that I did not know to…
MNWVSGSR+62 66 13k 2d

Related topics — sharing the tags metformin, needs a source, delayed gastric emptying

TopicParticipantsRepliesViewsActivity
Dizziness on standing and the electrolyte explanation — does this still hold?
The question in the title: Dizziness on standing and the electrolyte explanation — does this still hold? I will give what I have already checked below so nobody repeats it. Trying to work out what would count…
LCFVOOFC+89 94 18k 1mo
Common supplements people ask about, assessed one at a time
Common supplements people ask about, assessed one at a time — setting out what I have, and where I think it stops being reliable. A follow-up question about common supplements that I did not know to ask the…
NIASLCSFCM+101 107 28k 12h
Anaesthesia and elective surgery: the aspiration question — does this still hold?
Anaesthesia and elective surgery: the aspiration question — does this still hold? I have a specific reason for asking rather than idle curiosity, and the context is below. Asking about Anaesthesia and…
KHDBVSOFD+23 27 5.6k 17mo
Pregnancy as an absolute contraindication
Pregnancy as an absolute contraindication — setting out what I have, and where I think it stops being reliable. Pregnancy keeps being re-asked here and I think that is because the answer is conditional and…
MLKAEKPLBR+102 106 21k 14mo
[2026 update] Reflux appearing for the first time at a dose step
Posting this under the heading it deserves: Reflux appearing for the first time at a dose step Everything below is what sits behind that. Reporting something rather than asking about it, in case the pattern…
MDNLNB 2 980 7mo