Follow-up: A parcel that arrived warm: a decision process, not a verdict posts 31–60
This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1.
I will take the caveat as seriously as the claim, which is the point of putting it there.
I read post #31 twice before replying, because I had assumed the opposite.
Clarity is a weak test. A solution can lose a significant fraction of its active content to degradation or adsorption while remaining perfectly clear.
Post #31 answers the question as asked. The question underneath it is different.
Visible particulate is a strong signal in the other direction: it is a reason to stop and ask rather than to filter and proceed.
Clarity is a weak test. A solution can lose a significant fraction of its active content to degradation or adsorption while remaining perfectly clear.
Building on post #35 rather than restating it.
Visible particulate is a strong signal in the other direction: it is a reason to stop and ask rather than to filter and proceed.
Everything in post #35 holds. The case it does not cover is the one I have.
Clarity is a weak test. A solution can lose a significant fraction of its active content to degradation or adsorption while remaining perfectly clear.
Anyone who has looked at this more carefully, please correct the record.
On post #35 — agreed on the reasoning, with one qualification.
Clarity is a weak test. A solution can lose a significant fraction of its active content to degradation or adsorption while remaining perfectly clear.
Visible particulate is a strong signal in the other direction: it is a reason to stop and ask rather than to filter and proceed.
I would be interested in a counterexample if anyone has one.
Clarity is a weak test. A solution can lose a significant fraction of its active content to degradation or adsorption while remaining perfectly clear.
It is the kind of thing that is obvious once and never again.
Everything in post #38 holds. The case it does not cover is the one I have.
Visible particulate is a strong signal in the other direction: it is a reason to stop and ask rather than to filter and proceed.
Where I would look next, rather than where I would stop.
Clarity is a weak test. A solution can lose a significant fraction of its active content to degradation or adsorption while remaining perfectly clear.
Visible particulate is a strong signal in the other direction: it is a reason to stop and ask rather than to filter and proceed.
The step people skip is the one I have spelled out.
The arithmetic in post #44 is right; the assumption feeding it is the part to check.
Clarity is a weak test. A solution can lose a significant fraction of its active content to degradation or adsorption while remaining perfectly clear.
The conclusion is tentative; the arithmetic underneath it is not.
Clarity is a weak test. A solution can lose a significant fraction of its active content to degradation or adsorption while remaining perfectly clear.
That is all I can say without guessing.
Visible particulate is a strong signal in the other direction: it is a reason to stop and ask rather than to filter and proceed.
Nothing above should be read as advice about what anyone else should do.
Post #48 is right about the mechanism and I think understates the practical bit.
Temperature excursions in transit are common and are not all equal. A few hours warm is a different event from three days warm, and neither is visible in the vial on arrival.
Reading rather than contributing, but this is the most useful thread I have found on it.
Temperature excursions in transit are common and are not all equal. A few hours warm is a different event from three days warm, and neither is visible in the vial on arrival.
The general answer and the answer for your case may diverge here.
The arithmetic in post #53 is right; the assumption feeding it is the part to check.
Visible particulate is a strong signal in the other direction: it is a reason to stop and ask rather than to filter and proceed.
Collapsed as off-topic by two members at trust level 3 or above
Visible particulate is a strong signal in the other direction: it is a reason to stop and ask rather than to filter and proceed.
I have separated what I observed from what I concluded, which does not always happen.
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