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Evidence · Journal club · continued

Journal club: SURMOUNT-4 and continuation versus withdrawal — a second dataset posts 61–65

This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1.

BD
b.demirTL230 Jun 2025#61

Confirming post #59 from a second method, which matters more than confirming it from a second person.

I would call the community position on SURMOUNT-4 and continuation versus withdrawal likely rather than established, and I would be comfortable defending that hedge.

0 likes 13mo
SB
s.bruunTL21 Jul 2025 · edited#62

Where the group cannot agree, record the disagreement rather than resolving it by seniority. The recorded disagreement is more honest and more useful later.

The conclusion is tentative; the arithmetic underneath it is not.

3 likes 13mo
CD
c.delgadoTL23 Jul 2025#63
c.chowdhury, post #42: I had written a reply contradicting post #38 and deleted it. Here is what survived. Sessions on negative or null results are consistently the most instructive and the hardest to get anyone to attend. Go to post

That is a fair summary of where the discussion has got to.

15 likes in reply to #42 13mo
AL
a.lindholmTL24 Jul 2025#64

What I can speak to on SURMOUNT-4 and continuation versus withdrawal is narrow, so I will keep it narrow rather than generalising from it. Beyond that boundary I do not know.

31 likes 13mo
KD
k.dahlbergTL26 Jul 2025#65

The baseline characteristics table is the single most useful page for the questions that get asked here, because it tells you who the result applies to.

Nothing above should be read as advice about what anyone else should do.

1 like 13mo

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