Coming back to the opening post, because the follow-up matters more than the original answer.
The most useful reply I ever got about Designing a personal experiment was a request to state my units. It sounds like pedantry and it has saved me twice.
Coming back to the opening post, because the follow-up matters more than the original answer.
The most useful reply I ever got about Designing a personal experiment was a request to state my units. It sounds like pedantry and it has saved me twice.
The opening post is right about the mechanism and I think understates the practical bit.
Since Designing a personal experiment keeps coming up, it should probably be a maintained page rather than a recurring thread. I am happy to draft it if someone with more direct experience will review it.
Write down what you would accept as evidence that it did not work, before starting. That one sentence turns an anecdote into an experiment.
Multiple outcomes measured without a primary one means something will move. Nominate the primary in advance and report the rest as secondary.
Not the answer, but possibly the question that gets there.
Read the full topic (45 posts)
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An ABAB design with a data table and honest limitations — a second dataset
On the subject in the title: An ABAB design with a data table and honest limitations — a second dataset Working notes rather than a conclusion. Posting a small dataset on ABAB design. It is mine, it is…
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+106 | 118 | 25k | 4mo |
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Why most self-reports here are not experiments, and that is fine
Why most self-reports here are not experiments, and that is fine — that is the question, and I have not found it answered plainly anywhere I have looked. A question about what a single-person experiment can…
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2 | 46k | 11mo | |
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Designing a personal experiment that could change your mind — one year on
Designing a personal experiment that could change your mind — one year on — setting out what I have, and where I think it stops being reliable. Two things I would like separated before anyone answers on…
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+74 | 80 | 17k | 2d |
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Washout with a one-week half-life: the arithmetic
Washout with a one-week half-life: the arithmetic — setting out what I have, and where I think it stops being reliable. Washout: setting out the arithmetic in full, because I have had to do it twice and I…
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+90 | 96 | 44k | 20mo |
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An ABAB design with a data table and honest limitations
An ABAB design with a data table and honest limitations Writing it up because I had to work it out twice and would rather nobody else did. An honest uncertainty about ABAB design rather than a disguised…
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2 | 45k | 5mo |
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Coming back to: Column chemistry choices for a 40-residue peptide
On the subject in the title: Column chemistry choices for a 40-residue peptide Working notes rather than a conclusion. Column chemistry choices — I have the observation and I do not trust my interpretation of…
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2 | 43k | 16mo | |
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[2026 update] Reporting a disappointing outcome, and why it belongs here
On the subject in the title: Reporting a disappointing outcome, and why it belongs here Working notes rather than a conclusion. Proposing that Reporting a disappointing outcome deserves a maintained page…
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2 | 11k | 8mo | |
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How this community labels and discusses unrefereed work
How this community labels and discusses unrefereed work — that is the question, and I have not found it answered plainly anywhere I have looked. Reading an unrefereed manuscript properly, and asking whether I…
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+112 | 119 | 1.3k | 2y |
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Revisiting: List price versus negotiated price versus what you pay
Revisiting: List price versus negotiated price versus what you pay — setting out what I have, and where I think it stops being reliable. Working notes on List price versus negotiated price rather than a…
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+24 | 28 | 50k | 12mo |
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Follow-up: Why the titration planner refuses to produce a schedule below a floor
The question in the title: Why the titration planner refuses to produce a schedule below a floor I will give what I have already checked below so nobody repeats it. A follow-up question about titration…
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+120 | 146 | 14k | 10mo |