d.petrescu

TL2 · Lagos

Contributes reviews on supplier material. Based in Lagos.

Joined 28 December 2024 · last posted 3d

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Follow-up: Reading an interaction checker output critically Replied, post #65 · Practice › Interactions · 25 Jul 2026 · 0 likes SGLT2 inhibitors: frequently co-administered and relevant to renal and cardiovascular discussion, not to interactions. There is no pharmacokinetic interaction of concern.
Revisiting: Journal club: SURMOUNT-OSA and a hard endpoint in a soft field Replied, post #121 · Evidence › Journal club · 20 Jul 2026 · 16 likes Picking up post #120: that is the part I would want checked first. SURMOUNT-OSA has been discussed here with more heat than it deserves, mostly because two definitions…
Osteoarthritis and mechanical versus metabolic improvement Replied, post #5 · Clinical › Comorbidities · 7 Jul 2026 · 5 likes Worth separating two things that the opening post runs together. The question underneath osteoarthritis and mechanical versus metabolic is usually "how would I tell?"…
Coming back to: Batch date after test date, and other internal inconsistencies Replied, post #5 · Analytics › COA interpretation · 6 Jul 2026 · 1 like Reading back through the Batch date threads from last year, the same three questions come up every time and only one of them has ever been answered properly. That seems…
When your prescriber and the evidence disagree Replied, post #17 · Clinical › Prescriber conversations · 6 Jul 2026 · 1 like Where you disagree, saying so plainly and asking for the reasoning is better than agreeing and not following the plan. The rule of thumb is fine; the edge cases are…
An 18-month record including the parts that went badly Replied, post #53 · Outcomes › Progress reports · 28 Jun 2026 · 7 likes Post #52 answers the question as asked. The question underneath it is different. Adding a reference point for 18-month record. Mine is a single case, collected without…
[2026 update] Travelling with an injectable: documentation and practicalities Replied, post #38 · Access › International · 26 Jun 2026 · 29 likes Post #34 and I disagree about the size of the effect, not about the direction. Summaries lag badly in this area. Where a decision matters, read the current official…
Tracking intake honestly when appetite is absent Replied, post #74 · Nutrition & Training › Protein & intake · 26 Jun 2026 · 19 likes Adding the measurement that post #72 says would settle it. Distribution across the day appears to matter less than total for most outcomes, and it matters practically…
Peak-to-trough ratio at steady state for a weekly agent — the long version Replied, post #34 · Pharmacology › Pharmacokinetics · 26 Jun 2026 · 0 likes On post #30 — agreed on the reasoning, with one qualification. Where the Peak-to-trough ratio reasoning breaks down for me is the step from the group result to the…
Muscle cramps: the ordinary causes before the exotic ones — a second dataset Replied, post #13 · Practice › Side effects · 25 Jun 2026 · 7 likes Post #9 put the caveat in the right place and I want to underline it. The relationship between symptom burden and outcome is not what people assume. Feeling worse is…
Gastro-oesophageal reflux: improving or worsening? Replied, post #58 · Clinical › Comorbidities · 22 Jun 2026 · 0 likes Adding the boring version of gastro-oesophageal reflux, because the interesting version keeps getting posted and the boring one is usually right. Check the ordinary…
Muscle cramps: the ordinary causes before the exotic ones — a second dataset Replied, post #3 · marked as the solution · Practice › Side effects · 17 Jun 2026 · 7 likes Muscle cramps is worth one more sentence than it usually gets, and the sentence is the one about how the number was arrived at.