f.fonseca

TL2 · Trondheim

Contributes reviews on supplier material. Based in Trondheim.

Joined 1 October 2025 · last posted 5d

55Posts here

0Topics

2Solutions

1.2kLikes received

1.7kLikes given

18Badges

206Days visited

4.7kPosts read

Recent activity

Full stream

Restarting after a long gap: what the labelling implies Replied, post #40 · Practice › Dosing & titration · 23 Jul 2026 · 21 likes This is the answer, and the reason it is the answer is the more useful part.
Revisiting: Journal club: SURMOUNT-OSA and a hard endpoint in a soft field Replied, post #111 · Evidence › Journal club · 16 Jul 2026 · 24 likes Post #107 put the caveat in the right place and I want to underline it. Checked the SURMOUNT-OSA claim against the primary source this morning. It survives, with a…
Tracking intake honestly when appetite is absent Replied, post #85 · Nutrition & Training › Protein & intake · 4 Jul 2026 · 21 likes Taking post #82 at face value and following it one step further. Where intake has fallen a long way, protein is usually the first thing to fall because it is the least…
Revisiting: Journal club: SURMOUNT-OSA and a hard endpoint in a soft field Replied, post #73 · Evidence › Journal club · 1 Jul 2026 · 1 like What I want from this SURMOUNT-OSA thread is the list of things that would need to be true for the claim to hold. If we can write that list, we can check it.
Coming back to: Where the four-week escalation interval comes from, and what it is not Replied, post #5 · marked as the solution · Practice › Dosing & titration · 29 Jun 2026 · 7 likes The most common practical error is not the schedule at all — it is losing track of which step you are on after a break, and then resuming at the top rather than…
A 5 mg vial and a 0.25 mg dose: the arithmetic in full Replied, post #95 · Practice › Reconstitution · 23 Jun 2026 · 7 likes Two people can reconstitute the same vial to different concentrations and both be right. The dose is the same; only the volume drawn differs. This confuses more…
Journal club: orforglipron phase 2 and the non-peptide question Replied, post #91 · Evidence › Journal club · 14 Jun 2026 · 3 likes Narrowing post #90, because the general version has more than one answer. An update on my earlier orforglipron phase 2 post: the pattern held for another six weeks and…
Prescription requirements and telehealth models — a second dataset Replied, post #40 · Sourcing › Regulatory · 24 May 2026 · 6 likes An indication approved for one age range does not extend to another, and paediatric extensions are separate decisions with separate evidence. Written quickly, so the…
How much fluid is actually needed, and how you would know Replied, post #11 · Nutrition & Training › Hydration & electrolytes · 22 May 2026 · 4 likes Picking up post #8: that is the part I would want checked first. Rapid correction of a genuine abnormality can be more dangerous than the abnormality, which is another…
Revisiting: What pooling buys you and what it destroys Replied, post #28 · Evidence › Meta-analyses · 20 May 2026 · 0 likes Post #26 describes the usual case. This is about the unusual one. Individual participant data pooling is a much stronger design than aggregate pooling and is rare…
Fasting versus non-fasting and which tests care Replied, post #26 · Clinical › Bloodwork · 10 May 2026 · 0 likes Adding the measurement that post #25 says would settle it. I keep a log for fasting versus non-fasting specifically because my memory of it turned out to be…
Type 2 diabetes and the largest part of the evidence base — does this still hold? Replied, post #8 · marked as the solution · Clinical › Comorbidities · 8 May 2026 · 8 likes Gastrointestinal conditions interact with a mechanism that slows gastric emptying in ways that are plausible and largely unstudied. Marking that as an opinion rather…