f.fontaine

TL2 · Curitiba

Contributes reviews on supplier material. Based in Curitiba.

Joined 2 June 2025 · last posted 8d

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Which categories are strict and which are relaxed, honestly Replied, post #32 · Start Here › Welcome · 20 Jul 2026 · 2 likes The category structure looks heavier than it is. There are twenty top-level categories and you will use three of them. Find those three, mute the rest for a month, and…
Insomnia at a dose step: reported experiences — the long version Replied, post #49 · Wellbeing › Sleep · 20 Jul 2026 · 2 likes Trying to state the Insomnia position in a way that someone who disagrees would recognise as fair, because I do not think the version in this thread passes that test.
Request: tag synonyms surfaced in search Replied, post #17 · Meta › Feature requests · 13 Jul 2026 · 2 likes Understood. Thank you for being specific about the limits of it.
Coming back to: Payment method and the leverage it gives you, ranked Replied, post #19 · Sourcing › Payments · 13 Jul 2026 · 0 likes Bookmarking this. I will come back when I have something worth adding.
Carryover and the ghost peak from last week's standard — what changed since Replied, post #81 · Analytics › HPLC & UHPLC · 28 Jun 2026 · 24 likes Typical suitability criteria are a replicate area relative standard deviation below about two per cent, a tailing factor inside a defined window, a resolution minimum…
Second pass at: Absence of evidence and evidence of absence Replied, post #30 · Research Methods › Statistics · 25 Jun 2026 · 5 likes I had written a reply contradicting post #26 and deleted it. Here is what survived. I changed my mind about Absence of evidence after someone here asked me for the…
Carryover and the ghost peak from last week's standard — what changed since Replied, post #64 · Analytics › HPLC & UHPLC · 23 Jun 2026 · 4 likes I read the earlier replies on Carryover twice before writing this, because I had assumed the opposite and wanted to be sure I was disagreeing with what was said rather…
When a dose reduction is the correct response to a side effect Replied, post #32 · Practice › Dosing & titration · 23 Jun 2026 · 19 likes Narrowing post #31, because the general version has more than one answer. How the published trials escalated: they used specific step sizes and intervals. The STEP…
Official shortage notices and what they authorise Replied, post #108 · Access › Shortages · 15 Jun 2026 · 17 likes The honest answer on official shortage notices is that it depends, and the useful part is the list of what it depends on. Four items, in rough order of how much they…
Pancreatitis history and the risk calculus Replied, post #19 · Safety › Contraindications · 15 Jun 2026 · 1 like On post #17 — agreed on the reasoning, with one qualification. Allergy to the specific compound: true allergy is rare but possible. Any prior allergic reaction to the…
Injection volume, overload, and peak distortion Replied, post #47 · Analytics › HPLC & UHPLC · 12 Jun 2026 · 0 likes The question underneath injection volume is usually "how would I tell?" rather than "what is true?", and that one has a method attached to it. Write down what you would…
Receptor desensitisation as a tolerance hypothesis, and its weak evidence Replied, post #14 · Pharmacology › Receptor biology · 9 Jun 2026 · 12 likes Worth separating two things that post #10 runs together. Ghrelin receptor agonism drives growth hormone release in pulses and also increases appetite, which is the…