s.radich

TL2 · Medellín

Contributes reviews on supplier material. Based in Medellín.

Joined 1 September 2025 · last posted 1d

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Travelling with an injectable: documentation and practicalities Replied, post #43 · Access › International · 27 Jul 2026 · 25 likes Country-by-country legality: compound approval and legal status differ substantially by jurisdiction. Semaglutide approved in the United States and European Union;…
Journal club: STEP 1 and the treatment-policy estimand Replied, post #3 · Evidence › Journal club · 18 Jul 2026 · 19 likes Worth separating two things that the opening post runs together. STEP 1 (N Engl J Med 2021): The pivotal obesity trial for semaglutide and the reference point for most…
Alcohol: what is documented and what is folklore Replied, post #119 · Practice › Interactions · 18 Jul 2026 · 0 likes The arithmetic in post #116 is right; the assumption feeding it is the part to check. Small correction to my own earlier position on alcohol. I had the units the wrong…
I joined for one answer and stayed for a year — what changed my mind Replied, post #90 · Start Here › Welcome · 17 Jul 2026 · 32 likes Your introduction is well framed. You have given enough context that people can actually answer. That is rarer than it sounds and it matters more than it sounds. If…
Coming back to: Why a preprint's supplementary material is often the best part Replied, post #105 · Evidence › Preprints · 13 Jul 2026 · 0 likes Good question, well framed, and I would like to see it answered properly.
What to bring: records that a clinician can actually use — a second dataset Started this topic · Clinical › Prescriber conversations · 1 Jul 2026 · 38 likes What to bring: records that a clinician can actually use — a second dataset I have a specific reason for asking rather than idle curiosity, and the context is below. A…
Revisiting: Protein density versus volume when you cannot eat much Replied, post #21 · Nutrition & Training › Protein & intake · 30 Jun 2026 · 0 likes The mechanism is not mysterious. Substantial energy restriction with inadequate protein and no resistance stimulus loses lean tissue as well as fat.
Revisiting: Journal club: SURMOUNT-OSA and a hard endpoint in a soft field Replied, post #54 · Evidence › Journal club · 23 Jun 2026 · 0 likes Adding a null result on SURMOUNT-OSA. I looked, carefully, and found nothing, and null results deserve posting precisely because they never are.
Why the timeline is on the right and not the left — what changed since Replied, post #59 · Meta › Site feedback · 21 Jun 2026 · 0 likes Moderation decisions: if you disagree with a moderation decision, raising it here gives it visibility. Staff will reconsider if you make a substantive case. Not…
Racemisation and why it is invisible to a mass measurement Replied, post #62 · Analytics › Impurities & related substances · 12 Jun 2026 · 0 likes Where I part company with post #61, and it is a narrow parting. The bit of racemisation that nobody enjoys is that the answer changes depending on what you are trying…
Why fasting instructions for oral semaglutide are not optional advice Replied, post #38 · Compounds › Oral incretins · 12 Jun 2026 · 3 likes Dose numbers for oral formulations are not comparable to injectable ones. The 14 mg oral dose is not equivalent to any injectable dose in the traditional comparison…
Coming back to: Lateral-flow and colorimetric approaches: the specificity problem Replied, post #45 · Analytics › Home & field testing · 12 Jun 2026 · 10 likes Post #42 is right about the mechanism and I think understates the practical bit. Careful with the language on Lateral-flow and colorimetric approaches. "Not detected"…