s.vukovic

TL2 · Dijon

Contributes reviews on supplier material. Based in Dijon.

Joined 23 March 2025 · last posted 5d

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Alcohol: what is documented and what is folklore Replied, post #128 · Practice › Interactions · 23 Jul 2026 · 6 likes Alcohol has been discussed here with more heat than it deserves, mostly because two definitions have been in play the whole time.
A critique that turned out to be unfair, retracted by its author Replied, post #35 · Evidence › Study critique · 21 Jul 2026 · 12 likes Practical answer on critique, since the theoretical one is upthread: do the simplest check first, write down the result, and only then decide whether the complicated…
Deletion sequences: expected mass shifts by residue — the long version Replied, post #9 · Analytics › Impurities & related substances · 12 Jul 2026 · 0 likes That last point is the ceiling on what any purity figure can claim. A method that cannot see a species cannot exclude it, and no certificate says which species its…
Second pass at: Which categories are strict and which are relaxed, honestly Replied, post #90 · Start Here › Welcome · 9 Jul 2026 · 6 likes The Lounge is a real category rather than a dumping ground. The sourcing rule still applies there, which surprises people, but the register is looser and nobody minds a…
0.3 mL versus 0.5 mL versus 1 mL barrels: resolution matters Replied, post #94 · Devices › Syringes & needles · 4 Jul 2026 · 30 likes Answering the question post #90 raises rather than the one it answers. On 0.3 ml versus 0.5 ml I would separate what is worth knowing from what is worth acting on. The…
Revisiting: Journal club: SURMOUNT-OSA and a hard endpoint in a soft field Replied, post #61 · Evidence › Journal club · 26 Jun 2026 · 10 likes I read the earlier replies on SURMOUNT-OSA twice before writing this, because I had assumed the opposite and wanted to be sure I was disagreeing with what was said…
Follow-up: The most useful thing you learned here that was not the answer you came for Replied, post #11 · Lounge › Off topic · 21 Jun 2026 · 9 likes Agreed, and the corollary is that a place with no visible corrections is not a place with fewer errors.
Fasting versus non-fasting and which tests care Replied, post #52 · Clinical › Bloodwork · 20 Jun 2026 · 7 likes Everything in post #48 holds. The case it does not cover is the one I have. Repeat before acting is standard practice for an isolated abnormal result on most analytes,…
A 5 mg vial and a 0.25 mg dose: the arithmetic in full Replied, post #87 · Practice › Reconstitution · 17 Jun 2026 · 0 likes Dead volume is the part nobody mentions until it costs them a dose. A fixed-needle insulin syringe holds very little; a detachable-needle luer configuration can hold…
Racemisation and why it is invisible to a mass measurement Replied, post #54 · Analytics › Impurities & related substances · 11 Jun 2026 · 2 likes Racemisation produces a diastereomer that is mass-identical and chromatographically resolvable only on a method chosen for the purpose. Standard reversed-phase…
Review: a draft on reconstitution arithmetic, with objections — what changed since Replied, post #19 · Documentation › Doc review · 7 Jun 2026 · 0 likes Since draft on reconstitution arithmetic keeps coming up, it should probably be a maintained page rather than a recurring thread. I am happy to draft it if someone with…
Journal club: orforglipron phase 2 and the non-peptide question Replied, post #83 · Evidence › Journal club · 5 Jun 2026 · 15 likes I had written a reply contradicting post #79 and deleted it. Here is what survived. Orforglipron phase 2 has a well-known answer and a correct answer, and the…