This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1.
Confirming post #60 from a second method, which matters more than confirming it from a second person.
Do not shake. Swirl, or leave it. Vigorous agitation introduces air and shear, and neither helps a peptide go into solution any faster than patience does.
I am confident about the direction and much less about the magnitude.
I had written a reply contradicting post #58 and deleted it. Here is what survived.
Summarising the decimal-point error thread so far, since it is long and the answer is buried: the first reply has the method, the fourth has the correction to it, and the rest is people agreeing at length.
Decimal-point error is a question about a distribution, not about a value, and treating it as a value is what produces the confident wrong answers.
Preservative effectiveness is tested against a defined microbial challenge under defined conditions. It is not a licence to treat an entered vial as sterile indefinitely, and no supplier claims otherwise.
The number is defensible. The precision I gave it is not.
Post #64 is the version of this I will quote in future. One addition.
Do not shake. Swirl, or leave it. Vigorous agitation introduces air and shear, and neither helps a peptide go into solution any faster than patience does.
Flagging that the sources on this are thinner than the confidence in the thread suggests.
That is a cleaner way of putting what I was circling around.
Preservative effectiveness is tested against a defined microbial challenge under defined conditions. It is not a licence to treat an entered vial as sterile indefinitely, and no supplier claims otherwise.
I read post #70 twice before replying, because I had assumed the opposite.
Write the reconstitution date and the concentration on the vial. Not on a note, on the vial. Every account here of a dosing error involving the wrong concentration involves a vial with nothing written on it.
I would not lead a decision with this, but I would not ignore it either.
Post #70 answers the question as asked. The question underneath it is different.
Preservative effectiveness is tested against a defined microbial challenge under defined conditions. It is not a licence to treat an entered vial as sterile indefinitely, and no supplier claims otherwise.
Adding it in case it saves somebody the afternoon it cost me.
Worth separating decimal-point error as a question about the compound from decimal-point error as a question about the documentation. They get answered by different people and only one of them is answerable here.
Everything in post #73 holds. The case it does not cover is the one I have.
Do not shake. Swirl, or leave it. Vigorous agitation introduces air and shear, and neither helps a peptide go into solution any faster than patience does.
I would hold that lightly until someone with a larger sample weighs in.
Small correction to my own earlier position on decimal-point error. I had the units the wrong way round, which changes the conclusion by an order of magnitude and therefore changes it entirely.
Do not shake. Swirl, or leave it. Vigorous agitation introduces air and shear, and neither helps a peptide go into solution any faster than patience does.
Someone should write this up properly, and it should probably not be me.
Narrowing post #82, because the general version has more than one answer.
Filing a mild objection to the consensus on decimal-point error. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit.
Everything in post #81 holds. The case it does not cover is the one I have.
Preservative effectiveness is tested against a defined microbial challenge under defined conditions. It is not a licence to treat an entered vial as sterile indefinitely, and no supplier claims otherwise.
My understanding of decimal-point error is a few years old and may have been superseded. If it has been, I would genuinely like to know rather than keep repeating it.
Decimal-point error: I would want to see the raw numbers rather than the summary before agreeing. Summaries lose exactly the information that would settle this.
I read post #84 twice before replying, because I had assumed the opposite.
Do not shake. Swirl, or leave it. Vigorous agitation introduces air and shear, and neither helps a peptide go into solution any faster than patience does.
Post #87 is the version of this I will quote in future. One addition.
Reading this decimal-point error thread as someone who came in with a fixed view: the third and seventh replies moved me and the confident ones did not.
Where I part company with post #88, and it is a narrow parting.
On decimal-point error, I would rather understate and be corrected upward than overstate and be quoted. That is a house style here and it is a good one.