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Topic summary

How Janoshik, Medutest, PeptideMeter and VendorInvestigate differ

This is a generated summary. It shows the 9 most-liked posts from a topic of 131, in their original order, with the accepted answer included where one exists. It is a reading aid and it will miss nuance — the full topic is the record.
CP
citation_peakTL3Regular4 May 2025#45
resistance_first, post #25: PeptideMeter: purity analysis plus structured, dated supplier verification records. Produces both individual analytical results and verification records assessed over time rather than at a point in time. Go to post

Helpful, and easy to find again, which is half of what a good reply is.

32 likes in reply to #25 15mo
VB
v.baptistaTL27 May 2025#61

It does not extend to lots nobody has seen, it is not a recommendation, and it says nothing about anything other than what was measured.

I have deliberately not rounded that, because the rounding is where the argument starts.

29 likes 15mo
AP
ar.petrovTL29 May 2025#70
r.petrov, post #19: I would be cautious about generalising from the Janoshik example above. It is a good example. It is one example. Go to post

What I would tell a new member reading about Janoshik for the first time: the confident posts are not the reliable ones, and the reliable ones are longer.

28 likes in reply to #19 15mo
I
IsaksenTL3Regular10 May 2025#75
owen.brady, post #58: Where I part company with post #56, and it is a narrow parting. On Janoshik, the part that usually goes wrong is that the question is asked as though it has one answer. It has a range, and the width of the range is the interesting bit. If you can post the two or three numbers you are working from, several people here will check the… Go to post

Adding a reference point for Janoshik. Mine is a single case, collected without controls, and I am posting the method alongside it so it can be discounted appropriately.

31 likes in reply to #58 15mo
GE
g.ekstromTL211 May 2025 · edited#81

If you are new and reading this thread for the answer to Janoshik: the answer is conditional, the conditions are in the third reply, and the rest of the thread is worth skipping.

30 likes 15mo
SR
s.roosTL213 May 2025#87

On post #84 — agreed on the reasoning, with one qualification.

Where an independent figure and a declared figure differ by less than method repeatability, that is agreement rather than a small discrepancy.

31 likes 15mo
SP
s.poulsenTL3Regular13 May 2025#90

Taking post #87 at face value and following it one step further.

Medutest: combined purity and identity reporting. Appears throughout vendor documentation. Where a submission has been blind we note it because blind results are worth more than self-selected ones.

That is the practical version. The rigorous version is longer and says the same thing.

29 likes 15mo
B
batchlogTL3Regular15 May 2025#98

A record with four results over sixteen months is a thin record rather than a bad one, and the honest description says which.

I would put the burden of proof on the interesting explanation, not the dull one.

30 likes 14mo
MH
ms_hollowayTL4Mass spectrometrist19 May 2025#118

Sensible. I would want the same detail before I acted on it either.

32 likes 14mo

Read the full topic (131 posts)

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