This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1.
I had read the opposite somewhere and cannot now find where, which tells me something.
A new needle for each injection is not fussiness. A needle blunts on first use and a blunted needle is the reason the second injection hurts more than the first.
Two people can read the same figure differently here and both be reasonable.
This follows post #33 rather than contradicting it.
Filing a mild objection to the consensus on Pinch. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit.
I had written a reply contradicting post #33 and deleted it. Here is what survived.
If you have to inject at a different time of day than usual, that is a much smaller perturbation than it feels for a weekly compound with a week-long half-life.
Confirming post #33 from a second method, which matters more than confirming it from a second person.
Angle of injection: 90 degrees into pinched tissue ensures subcutaneous placement. It is not always necessary and shallower angles can work, but 90 degrees into a small pinch is the safest technique to learn first.
It took me longer than it should have to see that.
A new needle for each injection is not fussiness. A needle blunts on first use and a blunted needle is the reason the second injection hurts more than the first.
Understood, and I withdraw the assumption I opened with.
Appreciated. The plain phrasing does more work here than a longer post would.
I read post #39 twice before replying, because I had assumed the opposite.
Drawing up with one needle and injecting with another: a reasonable practice if you have extra needles. Fresh needle for injection reduces tissue drag and can decrease discomfort. Not necessary, but not harmful either.
I would want the raw data before agreeing with my own summary of it.
The failure mode on Pinch is boring rather than dramatic. It is almost always the step everyone assumes was done correctly because it is too simple to get wrong.
Narrowing post #42, because the general version has more than one answer.
If you have to inject at a different time of day than usual, that is a much smaller perturbation than it feels for a weekly compound with a week-long half-life.
One case, stated as one case.
Bleeding at the injection site: normal and usually minimal. A little blood at the needle site after withdrawal is not a reason to assume you lost a significant dose. The needle passed through tissue and there is a small amount of bleeding in the tract.
Summarising the Pinch thread so far, since it is long and the answer is buried: the first reply has the method, the fourth has the correction to it, and the rest is people agreeing at length.
Answering the question post #47 raises rather than the one it answers.
Injection discomfort: comes from needle gauge (finer = less discomfort), volume (smaller = less discomfort), temperature (room temperature or warmed is less uncomfortable than cold), and technique (smooth, purposeful injection is less uncomfortable than hesitant). All four are under your control.
Marking that as an opinion rather than a finding.
The arithmetic in post #51 is right; the assumption feeding it is the part to check.
A genuinely late dose: the labelling generally says that if the next dose is more than a couple of days away, take it as soon as you notice. If the next dose is close, skip it and resume the schedule. The reasoning follows from the long half-life; you are perturbing a slowly moving average.
I would put the burden of proof on the interesting explanation, not the dull one.
If you have to inject at a different time of day than usual, that is a much smaller perturbation than it feels for a weekly compound with a week-long half-life.
Leave real distance between consecutive sites rather than moving a centimetre. Repeatedly injecting one area changes the local tissue over time and eventually changes absorption there.
Needle length matters less than angle for subcutaneous delivery in most people. A short needle at ninety degrees and a longer one at forty-five put the material in roughly the same place.
The confident version of this sentence would be wrong, so here is the hedged one.
Adding the measurement that post #54 says would settle it.
Pinching a fold is useful for lean tissue and unnecessary elsewhere. The point is to keep the needle out of muscle, and whether you need to depends on the site and on you.
Worth reading the earlier posts in this thread before acting on mine.
If you have to inject at a different time of day than usual, that is a much smaller perturbation than it feels for a weekly compound with a week-long half-life.
I have three months of notes on Pinch and the honest summary is that the trend is real and the week-to-week numbers are noise. I nearly drew the opposite conclusion from the first fortnight.
The bit of Pinch that nobody enjoys is that the answer changes depending on what you are trying to decide with it. Say what the decision is and the thread will converge.