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Topic summary

Sample size intuition for a personal experiment — does this still hold?

This is a generated summary. It shows the 6 most-liked posts from a topic of 39, in their original order, with the accepted answer included where one exists. It is a reading aid and it will miss nuance — the full topic is the record.
CO
c.ostergaardTL2 Solution11 Mar 2026 · edited#7
m.strand_rph, post #2: Building on the opening post rather than restating it. Worth separating Sample size intuition as a question about the compound from Sample size intuition as a question about the documentation. They get answered by different people and only one of them is answerable here. Go to post

Where I have landed on Sample size intuition, having got it wrong once in public: the direction is clear, the magnitude is not, and anyone quoting a precise magnitude has borrowed it from somewhere that did not measure it.

7 likes in reply to #2 5mo
HS
hana.satoTL4 Moderator15 Mar 2026#8

Adding thanks rather than a view. I do not have a view worth the space.

26 likes 4mo
MM
methods_marginTL3Regular2 May 2026#20

A p-value is the probability of data at least this extreme given the null hypothesis. It is not the probability the hypothesis is false, and almost every plain-language gloss gets that backwards.

33 likes 3mo
I
IMainwaringTL3Regular27 May 2026#27

Quietly grateful for the plain phrasing. Not every thread gets that.

32 likes 2mo
FC
f.chowdhuryTL26 Jun 2026#30

Number needed to treat: how many people need to be treated to prevent one bad outcome or achieve one good outcome. More intuitive than relative risk reduction.

Not the whole picture, but the part of it I can speak to.

25 likes 2mo
SD
s.demirTL216 Jun 2026#33

Taking post #31 at face value and following it one step further.

I would put moderate confidence on the mainstream reading of Sample size intuition and no more. That is not scepticism for its own sake; it is where the sourcing actually stops.

26 likes 1mo

Read the full topic (39 posts)

Moved from N-of-1 designs by dr_okonkwo. Category placement is not obvious from outside and getting it wrong is expected. This topic will get better answers here. The move is recorded in the public log citing R7.

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