i.dumitru
TL2 · Izmir
Contributes reviews on supplier material. Based in Izmir.
Joined 31 January 2025 · last posted 4d
79Posts here
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Revisiting: Drawing from a pen cartridge with a syringe: how the risk profile changes Started this topic · Devices › Pens & autoinjectors · 29 Mar 2026 · 57 likes Revisiting: Drawing from a pen cartridge with a syringe: how the risk profile changes Writing it up because I had to work it out twice and would rather nobody else did.…
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Coming back to: Amylin analogue mechanism: satiety signalling separate from GLP-1 Started this topic · Compounds › Cagrilintide & amylin analogues · 15 Jul 2025 · 48 likes On the subject in the title: Amylin analogue mechanism: satiety signalling separate from GLP-1 Working notes rather than a conclusion. Trying to work out what would…
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Journal club: orforglipron phase 2 and the non-peptide question Replied, post #66 · Evidence › Journal club · 17 May 2026 · 33 likes Reframing orforglipron phase 2 slightly, because I think the disagreement is about the question rather than the answer. If the question is "does it happen", yes. If it…
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[2026 update] Does a peptide degrade silently, with no visual change? Replied, post #52 · Practice › Storage & stability · 27 Apr 2026 · 32 likes Adding the measurement that post #49 says would settle it. The thing about peptide that took me longest to accept is that a plausible mechanism is not evidence of an…
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Follow-up: Where the four-week escalation interval comes from, and what it is not Replied, post #47 · Practice › Dosing & titration · 18 Aug 2024 · 29 likes I read post #43 twice before replying, because I had assumed the opposite. Adding a small correction to the four-week escalation interval summary above rather than a…
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[2026 update] What we do not know about retatrutide, listed explicitly Replied, post #22 · Compounds › Retatrutide · 25 Jul 2025 · 28 likes Where I part company with post #20, and it is a narrow parting. Heart rate increased in a dose-dependent way in the phase 2 work. That is not a footnote — it is one of…
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