j.sorensen

TL2 · Rosario

Contributes reviews on supplier material. Based in Rosario.

Joined 5 January 2025 · last posted 1d

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Seven-day rolling means and why weekly readings mislead Replied, post #121 · Outcomes › Progress reports · 27 Jul 2026 · 1 like State the method before the numbers. Same scale, same time of day, same conditions — without that a series is a collection of readings rather than a measurement. It is…
What is genuinely unknown about long-term amylin agonism Replied, post #83 · Compounds › Cagrilintide & amylin analogues · 25 Jul 2026 · 20 likes Post #80 is the version of this I will quote in future. One addition. Cagrilintide is a long-acting amylin analogue, which puts it in a different mechanistic family…
I joined for one answer and stayed for a year — what changed my mind Replied, post #96 · Start Here › Welcome · 20 Jul 2026 · 6 likes If you are not sure which subcategory a question belongs in, post it in the closest one. A moderator will move it, the move is logged, and nothing bad happens to you.
Revisiting: Protein density versus volume when you cannot eat much Replied, post #65 · Nutrition & Training › Protein & intake · 14 Jul 2026 · 0 likes What I would check first on Protein density versus volume is whether the thing being measured moved or whether the way of measuring it moved. Those look identical in a…
Seven-day rolling means and why weekly readings mislead Replied, post #30 · Outcomes › Progress reports · 14 Jul 2026 · 6 likes Post #29 answers the question as asked. The question underneath it is different. State the method before the numbers. Same scale, same time of day, same conditions —…
Alcohol: what is documented and what is folklore Replied, post #110 · Practice › Interactions · 14 Jul 2026 · 14 likes Picking up post #109: that is the part I would want checked first. The thing about alcohol that took me longest to accept is that a plausible mechanism is not evidence…
Secretagogues and glucose tolerance: the mechanistic concern Replied, post #62 · Compounds › Secretagogues & GH axis · 5 Jul 2026 · 14 likes Research-use-only secretagogues are not approved for human use. That statement is doing real work in this subcategory, where the published evidence base is thinner than…
Follow-up: Prior authorisation: what the criteria usually require Replied, post #45 · Access › Insurance & coverage · 29 Jun 2026 · 3 likes Genuine question rather than a rhetorical one: has anyone here actually observed Prior authorisation, as opposed to read about it? The thread is long and I cannot tell.
Vomiting: when it is expected and when it is a reason to stop — one year on Replied, post #17 · Practice › Side effects · 26 Jun 2026 · 0 likes The relationship between symptom burden and outcome is not what people assume. Feeling worse is not evidence of a larger effect and feeling nothing is not evidence of…
Revisiting: Journal club: SURMOUNT-OSA and a hard endpoint in a soft field Replied, post #47 · Evidence › Journal club · 20 Jun 2026 · 0 likes A definition problem is doing most of the work in this SURMOUNT-OSA discussion. Once the term is pinned down I suspect the disagreement mostly goes away and what is…
Aggregate verification data across the directory, with caveats Replied, post #4 · Sourcing › Independent verification · 19 Jun 2026 · 8 likes The thing about aggregate verification data that took me longest to accept is that a plausible mechanism is not evidence of an effect. It is a reason to look, not a…
Muscle cramps: the ordinary causes before the exotic ones — a second dataset Started this topic · Practice › Side effects · 15 Jun 2026 · 15 likes Posting this under the heading it deserves: Muscle cramps: the ordinary causes before the exotic ones — a second dataset Everything below is what sits behind that.…