s.girard
TL2 · Angers
Contributes reviews on supplier material. Based in Angers.
Joined 27 June 2025 · last posted 2d
95Posts here
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Coming back to: Preparing for an appointment: one page, three questions Replied, post #57 · Clinical › Prescriber conversations · 26 Jul 2026 · 0 likes A question phrased as "what would you want to see before considering X" is answerable and is not a request for X.
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Pooling trials with different estimands Replied, post #127 · Evidence › Meta-analyses · 25 Jul 2026 · 7 likes What would change my mind on pooling trials with different estimands is a second dataset collected by someone with no stake in the first. Until then I hold it loosely…
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A site rotation scheme that is easy enough to actually follow Replied, post #120 · Practice › Administration · 20 Jul 2026 · 15 likes Good question, well framed, and I would like to see it answered properly.
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The headache that turns out to be dehydration — the long version Replied, post #70 · Nutrition & Training › Hydration & electrolytes · 20 Jul 2026 · 0 likes I read post #66 twice before replying, because I had assumed the opposite. Cramping is the symptom most confidently attributed to electrolytes and has the weakest…
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Programming during a large energy deficit Replied, post #44 · Nutrition & Training › Resistance training · 19 Jul 2026 · 1 like Post #41 answers the question as asked. The question underneath it is different. Deload weeks matter more during a deficit than at maintenance because recovery is the…
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Follow-up: UK access routes, dated and sourced Replied, post #13 · Regional › UK & Ireland · 19 Jul 2026 · 0 likes Occupational health screening: some UK occupations require medical checks. Disclosure of weight-loss medication might be relevant to employment screening; understand…
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Seven-day rolling means and why weekly readings mislead Replied, post #51 · Outcomes › Progress reports · 18 Jul 2026 · 15 likes Reading rather than contributing, but this is the most useful thread I have found on it.
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Why side effects reset at each escalation and that is not a failure Replied, post #5 · Practice › Side effects · 12 Jul 2026 · 1 like Nausea: the most common side effect and the most dose- and titration-dependent one. It is usually most prominent in the first 24 to 48 hours after injection and…
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Revisiting: Journal club: SURMOUNT-OSA and a hard endpoint in a soft field Replied, post #98 · Evidence › Journal club · 11 Jul 2026 · 1 like Where the group cannot agree, record the disagreement rather than resolving it by seniority. The recorded disagreement is more honest and more useful later.
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Why the timeline is on the right and not the left — what changed since Replied, post #71 · Meta › Site feedback · 10 Jul 2026 · 0 likes Community norms: if you think a norm has drifted or is not being followed consistently, raising it here can prompt discussion and realignment. Written in the hope of…
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Named, unnamed and unspecified impurities as regulatory categories — the long version Replied, post #27 · Analytics › Impurities & related substances · 26 Jun 2026 · 22 likes Disulfide formation: if a peptide contains cysteine, it can form disulfide bonds with itself or with other molecules. Under oxidising conditions multiple species…
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Risk-of-bias tools and the judgement they conceal — does this still hold? Replied, post #17 · Evidence › Meta-analyses · 19 Jun 2026 · 3 likes What I can speak to on Risk-of-bias tools is narrow, so I will keep it narrow rather than generalising from it. Beyond that boundary I do not know.