sterile_file
TL3 Regular · Wolverhampton, UK
Laboratory background. Comfortable with chromatography, cautious about extrapolating from a single certificate.
Joined 20 November 2024 · last posted 23h · groups: analytical-chemists
125Posts here
3Topics
2Solutions
4.5kLikes received
4.7kLikes given
29Badges
453Days visited
16kPosts read
Most-liked posts
-
Second pass at: What pooling buys you and what it destroys Replied, post #12 · Evidence › Meta-analyses · 24 Jan 2026 · 33 likes Speaking only to pooling buys as I have actually seen it, rather than as it is usually described: the effect is real, it is smaller than the thread suggests, and the…
-
Alcohol: what is documented and what is folklore Replied, post #23 · Practice › Interactions · 22 May 2026 · 32 likes The reason alcohol is hard to answer is that the obvious measurement and the relevant quantity are not the same thing, and substituting one for the other is silent.
-
Residual solvents and scavengers: what is looked for — what changed since Replied, post #6 · marked as the solution · Analytics › Impurities & related substances · 9 Feb 2026 · 32 likes This follows post #3 rather than contradicting it. Adding what did not work for me on Residual solvents and scavengers, since the failures never get written up and they…
-
Converting between mg/mL and units per dose, both directions — the long version Replied, post #66 · Practice › Reconstitution · 22 Apr 2026 · 31 likes Adding the measurement that post #65 says would settle it. Two people can reconstitute the same vial to different concentrations and both be right. The dose is the…
-
System suitability injections: if they failed, the run did not happen Replied, post #25 · Analytics › HPLC & UHPLC · 23 Aug 2025 · 31 likes Fair, and the limits you put on it are the part I will remember.
-
Forced degradation studies: designing one that is informative Replied, post #10 · Analytics › Method validation · 22 Feb 2026 · 30 likes Post #6 describes the usual case. This is about the unusual one. Specificity: the method can distinguish the intended compound from related impurities and degradation…
Where this member posts
Badges earned, in order
| Badge | Tier | Granted |
|---|---|---|
| Basic User | bronze | 22 Nov 2024 |
| First Reply | bronze | 22 Nov 2024 |
| Read the Guidelines | bronze | 26 Nov 2024 |
| First Link | bronze | 26 Nov 2024 |
| Welcome | bronze | 5 Dec 2024 |
| First Topic | bronze | 12 Dec 2024 |
| First Quote | bronze | 24 Dec 2024 |
| First Tag | bronze | 24 Dec 2024 |
| Reader | bronze | 27 Dec 2024 |
| Member | bronze | 11 Jan 2025 |
| Reads a COA | silver | 21 Jan 2025 |
| Sourced | bronze | 6 Feb 2025 |
| Generous | bronze | 13 Feb 2025 |
| First Solution | bronze | 2 Mar 2025 |
| Regular | silver | 5 Mar 2025 |
| Thank You | silver | 7 Mar 2025 |
| Editor | bronze | 18 Mar 2025 |
| Well Sourced | silver | 31 Mar 2025 |
| First Chromatogram | bronze | 2 Apr 2025 |
| Submitted a Sample | silver | 7 Apr 2025 |
| Relentlessly Generous | gold | 25 Apr 2025 |
| Good Post | silver | 29 Apr 2025 |
| Mass Accuracy | silver | 16 May 2025 |
| Nice Post | bronze | 1 Jun 2025 |
| Wiki Maintainer | gold | 27 Jun 2025 |
| Consistently Generous | silver | 1 Jul 2025 |
| Method First | silver | 10 Jul 2025 |
| Gives Back | gold | 1 Sep 2025 |
| Anniversary | silver | 20 Nov 2025 |