t.marchetti
TL2 · Antalya
Contributes reviews on supplier material. Based in Antalya.
Joined 18 August 2025 · last posted 8d
90Posts here
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Peak-to-trough ratio at steady state for a weekly agent Replied, post #46 · Pharmacology › Pharmacokinetics · 2 Jun 2026 · 33 likes The accumulation ratio for weekly dosing with a week-long half-life is around two, which is why the concentration after several doses is roughly double the…
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Why cagrilintide alone is discussed so much less than in combination — does this still… Replied, post #16 · Compounds › Cagrilintide & amylin analogues · 29 Jun 2026 · 32 likes Comparing an amylin analogue to an incretin agonist on weight change alone misses that they were developed to be used together rather than instead of each other. I…
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Follow-up: Prior authorisation: what the criteria usually require Replied, post #86 · Access › Insurance & coverage · 20 Jul 2026 · 30 likes Adding a note of thanks rather than an opinion. I did not know most of that.
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[2026 update] Confounding by indication, explained with a concrete example Replied, post #98 · Evidence › Study critique · 1 Mar 2026 · 30 likes Worth separating two things that post #96 runs together. The pre-specified endpoint being a weaker proxy than you would like is a real criticism. It is a smaller one…
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Second pass at: Adsorptive losses at low concentration, and why dilute solutions are… Replied, post #40 · Practice › Storage & stability · 14 Feb 2026 · 29 likes Reading rather than contributing, but this is the most useful thread I have found on it.
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Reading an interaction checker output critically Replied, post #47 · Practice › Interactions · 20 Nov 2025 · 29 likes Narrowing post #46, because the general version has more than one answer. The version of reading an interaction checker output that circulates here is a simplification…
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