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On the live site this tab tracks what you have not read. In this static rendering it shows every topic with activity in the last 45 days, which is the closest honest equivalent — we would rather explain the difference than pretend a static page knows your reading history.

414 topics · page 13 of 14

Topic	Participants	Replies	Views	Activity
Mood changes: monitoring, and when to involve a professional — what changed since Wellbeing › Mental health beginner friendly disordered eating mood Solved Mood changes: monitoring, and when to involve a professional — what changed since Writing it up because I had to work it out twice and would rather nobody else did. What changes if the standard account of…	+6	10	45k	25d
Second pass at: Leak-back after withdrawal and whether you lost a meaningful dose Practice › Administration subcutaneous injection needle gauge & length missed dose Second pass at: Leak-back after withdrawal and whether you lost a meaningful dose — setting out what I have, and where I think it stops being reliable. I have read the maintained page on this and I still have…	+18	22	2k	25d
Is "synergy" the right word for the combination data? Compounds › Cagrilintide & amylin analogues randomised trial cagrilintide effect size Is "synergy" the right word for the combination data? — that is the question, and I have not found it answered plainly anywhere I have looked. Setting out what I think I know about this compound and asking…	+5	9	13k	25d
Coming back to: Swirling versus inverting versus leaving it alone Practice › Reconstitution reconstitution concentration maths syringe units Solved Swirling versus inverting versus leaving it alone Writing it up because I had to work it out twice and would rather nobody else did. Swirling versus inverting versus leaving — I have the observation and I do…	+20	24	16k	26d
Revisiting: Journal club: SURMOUNT-1, read without the press release Evidence › Journal club number needed to treat effect size risk of bias journal club Solved On the subject in the title: Revisiting: Journal club: SURMOUNT-1, read without the press release Working notes rather than a conclusion. Session topic: SURMOUNT-1 ( N Engl J Med , 2022). Please read it…	+54	62	1.5k	26d
Personal or family history of medullary thyroid carcinoma Safety › Contraindications thyroid C-cell question pancreatitis pregnancy & planning Personal or family history of medullary thyroid carcinoma Writing it up because I had to work it out twice and would rather nobody else did. Asking about a contraindication as written rather than as…	+31	37	709	26d
About the Welcome category Start Here › Welcome onboarding guidelines beginner friendly Pinned Wiki Introductions, orientation, and the pinned reading list for new members. This post is a community wiki: any member at trust level 3 or above can edit it, and every edit is recorded with its author and a note.…	+3	8	11k	27d
Reading a syringe in poor light, and how to avoid needing to — what changed since Devices › Syringes & needles dead volume subcutaneous injection syringe units needle gauge & length Posting this under the heading it deserves: Reading a syringe in poor light, and how to avoid needing to — what changed since Everything below is what sits behind that. What changes if the standard account of…	+3	7	27k	27d
Journal club: STEP 3 and the intensive behavioural therapy floor Evidence › Journal club randomised trial journal club effect size risk of bias Posting this under the heading it deserves: Journal club: STEP 3 and the intensive behavioural therapy floor Everything below is what sits behind that. Two things I would like separated before anyone answers…	+6	10	13k	28d
How this community escalates rather than diagnoses — does this still hold? Safety › Adverse events pancreatitis delayed gastric emptying hypoglycaemia vomiting Solved Wiki The question in the title: How this community escalates rather than diagnoses — does this still hold? I will give what I have already checked below so nobody repeats it. Working notes on community escalates…		4	90	29d
Does dual agonism explain the effect size, or is it dose? Compounds › Tirzepatide SURPASS programme SURMOUNT programme tirzepatide randomised trial Solved Does dual agonism explain the effect size, or is it dose? I have a specific reason for asking rather than idle curiosity, and the context is below. A question about dual agonism that I think has a definite…	+62	68	2.6k	29d
Follow-up: Search filters: what is missing Meta › Site feedback guidelines site feedback moderation On the subject in the title: Search filters: what is missing Working notes rather than a conclusion. A follow-up question about Search filters that I did not know to ask the first time. The earlier thread…	+119	141	1.6k	29d
Follow-up: How to disagree with an answer you were given, well Start Here › How to Ask onboarding worked example guidelines site feedback How to disagree with an answer you were given, well I have a specific reason for asking rather than idle curiosity, and the context is below. Question in the title and the context underneath, in the order the…		2	16k	30d
Cold solution and stinging: the simplest fix Practice › Administration injection site rotation subcutaneous injection missed dose Posting this under the heading it deserves: Cold solution and stinging: the simplest fix Everything below is what sits behind that. An honest uncertainty about cold solution and stinging rather than a…	+35	39	8.2k	30d
Second pass at: Programming during a large energy deficit Nutrition & Training › Resistance training DXA lean mass loss fatigue Posting this under the heading it deserves: Second pass at: Programming during a large energy deficit Everything below is what sits behind that. Two things I would like separated before anyone answers on…	+44	48	632	30d
Stability of BPC-157 in solution: what has been measured Compounds › Repair & healing peptides BPC-157 observational data needs a source TB-500 Stability of BPC-157 in solution: what has been measured — setting out what I have, and where I think it stops being reliable. Something about stability of BPC-157 does not reconcile and I would like a second…		2	805	30d
Analytical identity of BPC-157: a 15-mer with a simple mass — does this still hold? Compounds › Repair & healing peptides needs a source preprint BPC-157 Analytical identity of BPC-157: a 15-mer with a simple mass — does this still hold? — that is the question, and I have not found it answered plainly anywhere I have looked. The question about Analytical…	+28	33	1.6k	1mo
A plateau that disappeared when I changed how I measured — the long version Outcomes › Progress reports effect size data table long read A plateau that disappeared when I changed how I measured — the long version — setting out what I have, and where I think it stops being reliable. A narrow question about plateau, deliberately narrow, because…	+49	54	9.4k	1mo
Coming back to: What the published dose-response for semaglutide actually looks like above 2.4 mg Compounds › Semaglutide effect size type 2 diabetes semaglutide STEP programme Solved The question in the title: What the published dose-response for semaglutide actually looks like above 2.4 mg I will give what I have already checked below so nobody repeats it. I would like to know what…	+23	27	9.9k	1mo
Pinch or no pinch, and how needle length changes the answer — the long version Practice › Administration injection site rotation injection site reaction missed dose aseptic technique On the subject in the title: Pinch or no pinch, and how needle length changes the answer — the long version Working notes rather than a conclusion. A narrow question about Pinch, deliberately narrow, because…	+75	79	1.5k	1mo
Gastro-oesophageal reflux: improving or worsening? Clinical › Comorbidities PCOS obstructive sleep apnoea MASH / hepatic steatosis chronic kidney disease Solved The question in the title: Gastro-oesophageal reflux: improving or worsening? I will give what I have already checked below so nobody repeats it. Collecting what is known about gastro-oesophageal reflux in…	+54	58	8.2k	1mo
[2026 update] A vial that will not fully dissolve: what to check and in what order Practice › Reconstitution concentration maths dead volume bacteriostatic water syringe units Solved Posting this under the heading it deserves: A vial that will not fully dissolve: what to check and in what order Everything below is what sits behind that. Practical question with the units stated, because I…	+114	128	20k	1mo
Run-in periods and the population they select Evidence › Trials surrogate endpoints discontinuation & dropout estimand randomised trial On the subject in the title: Run-in periods and the population they select Working notes rather than a conclusion. An honest uncertainty about run-in periods rather than a disguised assertion. I do not know…	+130	142	7.3k	1mo
How to disagree with an answer you were given, well Start Here › How to Ask beginner friendly site feedback worked example guidelines Solved Wiki How to disagree with an answer you were given, well — that is the question, and I have not found it answered plainly anywhere I have looked. Question in the title and the context underneath, in the order the…	+9	13	1.6k	1mo
Second pass at: Temperature logging at home: what is worth the effort Practice › Storage & stability temperature excursion cloudy or discoloured solution freeze-thaw cold chain Posting this under the heading it deserves: Second pass at: Temperature logging at home: what is worth the effort Everything below is what sits behind that. Posting a small dataset on Temperature logging. It…	+4	8	29k	1mo
A checklist for reading a certificate in under two minutes Analytics › COA interpretation certificate of analysis batch & lot numbers amino acid analysis Solved A checklist for reading a certificate in under two minutes — setting out what I have, and where I think it stops being reliable. I would like to understand what this number means before I repeat it anywhere.…	+39	46	38k	1mo
Reference intervals: how they are constructed and why one in twenty flags Clinical › Bloodwork HbA1c thyroid function eGFR & renal function lipase & amylase Under review Reference intervals: how they are constructed and why one in twenty flags — setting out what I have, and where I think it stops being reliable. Reference intervals: what I expected, what I found, and the gap…	+104	119	30k	1mo
Journal club: SELECT, absolute risk, and how it was reported Evidence › Journal club journal club estimand randomised trial effect size Journal club: SELECT, absolute risk, and how it was reported Writing it up because I had to work it out twice and would rather nobody else did. A question about what the numbers mean rather than what they…		2	52k	1mo
Batch numbers that do not match the vial label — what changed since Sourcing › Red flags underdosing documentation quality disputed moderation Solved On the subject in the title: Batch numbers that do not match the vial label — what changed since Working notes rather than a conclusion. What changes if the standard account of Batch numbers is wrong? I ask…	+39	43	14k	1mo
An appeal that succeeded, with the letter structure — the long version Access › Insurance & coverage appeals formulary insurance An appeal that succeeded, with the letter structure — the long version — setting out what I have, and where I think it stops being reliable. A narrow question about appeal, deliberately narrow, because the…	+113	136	32k	1mo