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Evidence · Preprints

A preprint whose numbers changed substantially at publication — what changed since

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b.aaltoTL225 Jul 2025#1

On the subject in the title: A preprint whose numbers changed substantially at publication — what changed since Working notes rather than a conclusion.

A preprint question rather than a question about the finding in it.

The manuscript is on a preprint server, dated, with a version number I have written down. It has not been through review and the authors say so in the header. What I cannot work out is how much weight that leaves it carrying.

I would like the reasoning rather than a rule. "Wait for publication" is not usable when the publication may be two years away and the question is now.

9 likes 12mo
RV
r.vukovicTL223 Aug 2025#2

Unrefereed work is not worthless and a great deal of it survives review substantially unchanged. That is the accurate framing and it is not a licence to treat it as final.

14 likes 11mo
KO
k.otieno_statsTL3Statistician13 Sep 2025 · edited#3

Unrefereed work is not worthless. A great deal of it survives review substantially unchanged. It is also the case that the version appearing in a journal frequently has different numbers, and the changes are not random — they tend to be in the direction of a smaller effect and a more careful claim.

Worth reading the earlier posts in this thread before acting on mine.

28 likes 10mo
ES
e.steinerTL21 Oct 2025#4
b.aalto, post #1: On the subject in the title: A preprint whose numbers changed substantially at publication — what changed since Working notes rather than a conclusion. A preprint question rather than a question about the finding in it. The manuscript is on a preprint server, dated, with a version number I have written down. It has not been through… Go to post

Where I part company with the opening post, and it is a narrow parting.

A preprint that has been up for two years without appearing in a journal is telling you something, and it is not necessarily that the work is bad.

The confident version of this sentence would be wrong, so here is the hedged one.

0 likes in reply to #1 10mo
SS
system_suitabilityTL3Analytical chemist18 Oct 2025#5

If you cite a preprint in a maintained document here, the convention is to label it in the sentence and to note the check date. The document review will catch the update.

2 likes 9mo
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n.ibarraTL23 Nov 2025#6

Do not build anything on a preprint that you would mind rebuilding: if the preprint later changes substantially in revision or shows different results when published, your reasoning based on the preprint needs to be revised.

9 likes 9mo
PI
p.iyer_pharmdTL3Pharmacist19 Nov 2025#7

Confirming post #6 from a second method, which matters more than confirming it from a second person.

Reading a preprint properly means doing some of the reviewer's job: methods first, then whether the analysis matches the plan, then the conclusion.

I would put the burden of proof on the interesting explanation, not the dull one.

20 likes 8mo
ZO
z.okonkwoTL24 Dec 2025#8
k.otieno_stats, post #3: Unrefereed work is not worthless. A great deal of it survives review substantially unchanged. It is also the case that the version appearing in a journal frequently has different numbers, and the changes are not random — they tend to be in the direction of a smaller effect and a more careful claim. Worth reading the earlier posts in… Go to post

Understood. Thank you for being specific about the limits of it.

0 likes in reply to #3 8mo

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